| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Iron Man | - | - | - | $2,274,126 | 174 | $2,446,286 | Apr 30 | United International Pictures | false |
| 2 | Indiana Jones and the Kingdom of the Crystal Skull | - | - | - | $1,769,218 | 261 | $2,038,867 | May 22 | United International Pictures | false |
| 3 | Phobia | - | - | - | $1,205,949 | 111 | $2,435,026 | Apr 24 | - | false |
| 4 | The Chronicles of Narnia: Prince Caspian | - | - | - | $1,002,033 | 216 | $2,303,423 | May 29 | Walt Disney Pictures | false |
| 5 | Teng's Angel | - | - | - | $931,168 | 91 | $928,983 | May 1 | Mongkol Film Company | false |
| 6 | Speed Racer | - | - | - | $507,313 | 132 | $810,811 | May 8 | Warner Bros. | false |
| 7 | Memory 2008 Re-release | - | - | - | $403,035 | 70 | $402,104 | May 15 | - | false |
| 8 | What Happens in Vegas | - | - | - | $399,816 | 43 | $428,570 | May 8 | 20th Century Fox International | false |
| 9 | Never Back Down | - | - | - | $192,290 | 42 | $190,524 | May 15 | Mongkol Film Company | false |
| 10 | Deception | - | - | - | $131,873 | 30 | $131,873 | May 8 | M Pictures | false |
| 11 | Penelope | - | - | - | $125,505 | 22 | $125,304 | May 15 | M Pictures | false |
| 12 | The Forbidden Kingdom | - | - | - | $117,612 | 131 | $1,574,506 | Apr 18 | Mongkol Major | false |
| 13 | 21 | - | - | - | $83,216 | 1 | $120,971 | May 15 | Sony Pictures Releasing | false |
| 14 | Three Kingdoms | - | - | - | $62,311 | 40 | $228,549 | Apr 24 | - | false |
| 15 | The Eye | - | - | - | $44,735 | 20 | $48,628 | Apr 30 | M Pictures | false |
| 16 | Juno | - | - | - | $42,363 | 7 | $46,358 | May 15 | Mongkol Major | false |
| 17 | Nim's Island | - | - | - | $37,848 | 45 | $118,714 | Apr 24 | Mongkol Film Company | false |
| 18 | Superhero Movie | - | - | - | $32,248 | 54 | $452,494 | Apr 17 | M Pictures | false |
| 19 | In the Name of the King: A Dungeon Siege Tale | - | - | - | $23,100 | 43 | $132,421 | Apr 24 | United International Pictures | false |
| 20 | Pathology | - | - | - | $20,731 | 7 | $34,650 | May 29 | M Pictures | false |
| 21 | The Counterfeiters | - | - | - | $9,632 | 1 | $9,632 | May 8 | J-Bics | false |
| 22 | The Leap Years | - | - | - | $8,000 | 5 | $13,510 | May 29 | Mongkol Major | false |
| 23 | Untraceable | - | - | - | $7,026 | 14 | $43,923 | Apr 24 | - | false |
| 24 | Horton Hears a Who! | - | - | - | $3,568 | 65 | $192,762 | Apr 17 | 20th Century Fox International | false |
| 25 | Always: Sunset on Third Street 2 | - | - | - | $3,236 | 1 | $29,740 | Mar 27 | Mongkol Major | false |
| 26 | My Blueberry Nights | - | - | - | $2,118 | 6 | $50,885 | Mar 20 | M Pictures | false |
| 27 | Orahun | - | - | - | $1,180 | 55 | $714,881 | Apr 10 | - | false |
| 28 | Dream Team | - | - | - | $708 | 62 | $1,111,907 | Apr 3 | RS Film & Distribution | false |
| 29 | Once | - | - | - | $357 | 1 | $38,670 | Feb 28 | Mongkol Major | false |
