| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | What Happens in Vegas | - | - | - | $178,177 | 6 | $279,982 | May 16 | Universal Pictures International (UPI) | false |
| 2 | Ice Age 2: The Meltdown | - | - | - | $151,468 | 3 | $665,174 | Apr 7 | Universal Pictures International (UPI) | false |
| 3 | 21 | - | - | - | $134,368 | 2 | $166,987 | May 2 | ACME | false |
| 4 | Indiana Jones and the Kingdom of the Crystal Skull | - | - | - | $131,984 | 7 | $269,063 | May 22 | Universal Pictures International (UPI) | false |
| 5 | Iron Man | - | - | - | $119,423 | 4 | $158,882 | May 1 | Universal Pictures International (UPI) | false |
| 6 | Fool's Gold | - | - | - | $77,176 | 2 | $95,143 | May 9 | Garsu Pasaulio Irasai | false |
| 7 | Garfield: A Tail of Two Kitties | - | - | - | $75,154 | 2 | $358,900 | Jul 28 | Universal Pictures International (UPI) | false |
| 8 | The Eye | - | - | - | $45,124 | 1 | $48,118 | May 9 | ACME | false |
| 9 | Speed Racer | - | - | - | $35,542 | 6 | $45,663 | May 16 | Garsu Pasaulio Irasai | false |
| 10 | The Game Plan | - | - | - | $32,020 | - | $184,002 | Apr 4 | Universal Pictures International (UPI) | false |
| 11 | Horton Hears a Who! | - | - | - | $29,812 | 4 | $355,215 | Mar 21 | Universal Pictures International (UPI) | false |
| 12 | 99 Francs | - | - | - | $29,411 | 1 | $66,445 | Apr 25 | ACME | false |
| 13 | Drillbit Taylor | - | - | - | $19,888 | 1 | $96,658 | Apr 18 | Universal Pictures International (UPI) | false |
| 14 | Sleuth | - | - | - | $14,355 | 1 | $18,636 | May 2 | ACME | false |
| 15 | My Blueberry Nights | - | - | - | $11,050 | 1 | $57,310 | Apr 18 | ACME | false |
| 16 | Katyn | - | - | - | $10,243 | - | $25,878 | Apr 25 | MEED Films | false |
| 17 | Shutter | - | - | - | $7,277 | - | $137,133 | Mar 28 | Universal Pictures International (UPI) | false |
| 18 | The Bucket List | - | - | - | $7,023 | - | $158,857 | Mar 28 | Garsu Pasaulio Irasai | false |
| 19 | Cassandra's Dream | - | - | - | $5,986 | - | $11,056 | May 23 | ACME | false |
| 20 | The Ruins | - | - | - | $5,882 | 1 | $77,047 | Apr 11 | Universal Pictures International (UPI) | false |
| 21 | Rambo | - | - | - | $4,697 | 1 | $29,353 | Apr 25 | Garsu Pasaulio Irasai | false |
| 22 | The Other Boleyn Girl | - | - | - | $2,947 | - | $122,247 | Mar 7 | Universal Pictures International (UPI) | false |
| 23 | Mokykla Be Uniformos | - | - | - | $2,373 | - | $4,069 | May 9 | - | false |
| 24 | The Diving Bell and the Butterfly | - | - | - | $1,971 | 1 | $19,236 | Apr 18 | ACME | false |
| 25 | Street Kings | - | - | - | $1,349 | 1 | $29,309 | Apr 11 | Universal Pictures International (UPI) | false |
| 26 | Untraceable | - | - | - | $1,039 | - | $24,317 | Apr 18 | ACME | false |
| 27 | Vantage Point | - | - | - | $954 | - | $60,852 | Apr 4 | ACME | false |
| 28 | No Country for Old Men | - | - | - | $521 | - | $126,702 | Feb 22 | Universal Pictures International (UPI) | false |
| 29 | The Fox and the Child | - | - | - | $466 | 1 | $2,075 | May 16 | ACME | false |
| 30 | 10,000 BC | - | - | - | $398 | - | $307,989 | Mar 14 | Garsu Pasaulio Irasai | false |
| 31 | The Simpsons Movie | - | - | - | $361 | - | $890,890 | Jul 27 | Universal Pictures International (UPI) | false |
| 32 | Kolekcioniere | - | - | - | $344 | 1 | $4,328 | Apr 6 | - | false |
| 33 | The Water Horse | - | - | - | $331 | - | $29,247 | Mar 21 | ACME | false |
| 34 | Definitely, Maybe | - | - | - | $217 | - | $75,604 | Mar 28 | Universal Pictures International (UPI) | false |
