| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Indiana Jones and the Kingdom of the Crystal Skull | - | - | - | $43,709,713 | 540 | $50,771,279 | May 22 | Paramount Pictures International | false |
| 2 | Iron Man | - | - | - | $30,721,072 | 500 | $34,282,266 | May 2 | Paramount Pictures International | false |
| 3 | What Happens in Vegas | - | - | - | $12,056,983 | 405 | $15,639,183 | May 9 | 20th Century Fox International | false |
| 4 | Forgetting Sarah Marshall | - | - | - | $8,480,427 | 395 | $15,145,227 | Apr 25 | Universal Pictures International (UPI) | false |
| 5 | Nim's Island | - | - | - | $6,264,396 | 393 | $7,784,514 | May 2 | Universal Pictures International (UPI) | false |
| 6 | Made of Honor | - | - | - | $4,551,861 | 348 | $4,699,956 | May 2 | Sony Pictures Releasing | false |
| 7 | Speed Racer | - | - | - | $2,828,910 | 457 | $3,240,114 | May 9 | Warner Bros. | false |
| 8 | Doomsday | - | - | - | $1,987,904 | 259 | $2,061,794 | May 9 | Universal Pictures International (UPI) | false |
| 9 | In Bruges | - | - | - | $1,887,353 | 270 | $6,250,913 | - | Universal Pictures International (UPI) | false |
| 10 | The Eye | - | - | - | $1,674,502 | 370 | $3,648,328 | Apr 24 | Lionsgate | false |
| 11 | 21 | - | - | - | $1,630,134 | 356 | $10,913,306 | Apr 11 | Sony Pictures Releasing | false |
| 12 | Happy-Go-Lucky | - | - | - | $1,216,701 | 114 | $3,105,262 | Apr 18 | Momentum Pictures | false |
| 13 | Persepolis | - | - | - | $997,174 | 47 | $1,801,233 | Apr 25 | Optimum Releasing | false |
| 14 | Fool's Gold | - | - | - | $707,812 | 398 | $4,753,969 | Apr 18 | Warner Bros. | false |
| 15 | The Spiderwick Chronicles | - | - | - | $665,420 | 496 | $20,855,961 | Mar 21 | Paramount Pictures International | false |
| 16 | Caramel | - | - | - | $628,418 | 49 | $902,814 | May 16 | Momentum Pictures | false |
| 17 | Step Up 2: The Streets | - | - | - | $543,761 | 377 | $20,955,124 | Mar 21 | Universal Pictures International (UPI) | false |
| 18 | Son of Rambow | - | - | - | $483,474 | 311 | $8,272,930 | Apr 4 | Optimum Releasing | false |
| 19 | Horton Hears a Who! | - | - | - | $429,568 | 509 | $17,255,430 | Mar 21 | 20th Century Fox International | false |
| 20 | Bhoothnath | - | - | - | $387,347 | 34 | $404,071 | May 9 | Eros Worldwide | false |
| 21 | Charlie Bartlett | - | - | - | $376,422 | 202 | $388,748 | May 16 | Verve Pictures | false |
| 22 | Smart People | - | - | - | $355,567 | 73 | $400,097 | May 16 | Icon Film Distribution Australia | false |
| 23 | Shutter | - | - | - | $340,176 | 65 | $368,489 | May 16 | 20th Century Fox International | false |
| 24 | Street Kings | - | - | - | $280,510 | 353 | $2,737,444 | Apr 18 | 20th Century Fox International | false |
| 25 | Kuruvi | - | - | - | $263,919 | 16 | $263,919 | May 2 | Ayngaran International | false |
| 26 | Jannat: In Search of Heaven... | - | - | - | $261,068 | 21 | $302,341 | May 16 | Tip Top Entertainment (TTE) | false |
| 27 | Deception | - | - | - | $249,917 | 291 | $1,019,414 | Apr 25 | Entertainment Film Distributors | false |
| 28 | 27 Dresses | - | - | - | $244,826 | 434 | $13,458,037 | Mar 27 | 20th Century Fox International | false |
| 29 | Tashan | - | - | - | $224,473 | 46 | $702,087 | Apr 25 | Yash Raj Films | false |
| 30 | The Oxford Murders | - | - | - | $199,514 | 62 | $453,890 | Apr 25 | Odeon Sky Filmworks | false |
| 31 | Joy Division | - | - | - | $169,572 | 6 | $182,842 | May 2 | - | false |
| 32 | Cassandra's Dream | - | - | - | $169,328 | 50 | $239,955 | May 23 | Optimum Releasing | false |
| 33 | Underdog | - | - | - | $153,456 | 173 | $3,038,323 | Feb 1 | Walt Disney Pictures | false |
| 34 | Outpost | - | - | - | $145,951 | 51 | $146,104 | May 16 | Vertigo Films | false |
| 35 | The Game Plan | - | - | - | $142,972 | 368 | $8,477,553 | Mar 7 | Walt Disney Pictures | false |
| 36 | P2 | - | - | - | $141,787 | 124 | $141,787 | May 2 | Tartan | false |
| 37 | Leatherheads | - | - | - | $138,953 | 335 | $2,177,829 | Apr 11 | Universal Pictures International (UPI) | false |
| 38 | Honeydripper | - | - | - | $134,138 | 18 | $168,534 | May 9 | Axiom Films | false |
| 39 | Where in the World Is Osama Bin Laden? | - | - | - | $128,987 | 38 | $142,956 | May 9 | Optimum Releasing | false |
| 40 | Shine a Light | - | - | - | $119,484 | 150 | $1,327,400 | Apr 11 | 20th Century Fox International | false |
| 41 | The Diving Bell and the Butterfly | - | - | - | $110,363 | 41 | $1,820,554 | Feb 8 | Pathé | false |
| 42 | The Orphanage | - | - | - | $106,972 | 114 | $3,394,112 | Mar 21 | Optimum Releasing | false |
| 43 | XXY | - | - | - | $96,064 | 8 | $122,577 | May 9 | Peccadillo Pictures | false |
| 44 | Heartbeat Detector | - | - | - | $94,556 | 6 | $158,771 | May 16 | Trinity Filmed Entertainment | false |
| 45 | The Other Boleyn Girl | - | - | - | $88,919 | 355 | $9,709,885 | Mar 7 | Universal Pictures International (UPI) | false |
| 46 | The Bank Job | - | - | - | $79,610 | 325 | $8,068,923 | Feb 28 | Lionsgate | false |
| 47 | Welcome to the Sticks | - | - | - | $60,607 | 45 | $245,406 | Apr 1 | Pathé | false |
| 48 | A Secret | - | - | - | $60,513 | 3 | $68,262 | May 9 | Arrow Films | false |
| 49 | My Brother is an Only Child | - | - | - | $60,278 | 25 | $648,813 | Apr 4 | Revolver Entertainment | false |
| 50 | Mr. White Mr. Black | - | - | - | $51,321 | 11 | $51,321 | May 2 | Eros Worldwide | false |
| 51 | Timber Falls | - | - | - | $49,508 | 22 | $53,335 | May 23 | Scanbox Entertainment | false |
| 52 | Flashbacks of a Fool | - | - | - | $45,901 | 272 | $900,575 | Apr 18 | Walt Disney Pictures | false |
| 53 | Lars and the Real Girl | - | - | - | $41,966 | 26 | $891,507 | Mar 21 | Verve Pictures | false |
| 54 | Drillbit Taylor | - | - | - | $39,078 | 303 | $4,452,750 | Mar 28 | Paramount Pictures International | false |
| 55 | A Deal Is a Deal | - | - | - | $37,116 | 380 | $606,968 | Apr 25 | Worldwide Bonus Entertainment | false |
| 56 | Manufactured Landscapes | - | - | - | $36,407 | 6 | $41,503 | May 9 | British Film Institute (BFI) | false |
| 57 | Love in the Time of Cholera | - | - | - | $30,415 | 73 | $731,049 | Mar 21 | Momentum Pictures | false |
| 58 | Terror's Advocate | - | - | - | $29,439 | 3 | $35,887 | May 16 | Artificial Eye | false |
| 59 | Grindhouse | - | - | - | $25,995 | 45 | $192,369 | Mar 28 | Momentum Pictures | false |
| 60 | Never Back Down | - | - | - | $25,666 | 326 | $4,281,726 | Apr 4 | Momentum Pictures | false |
| 61 | Juno | - | - | - | $22,778 | 373 | $19,223,794 | Feb 8 | 20th Century Fox International | false |
| 62 | The Last Mistress | - | - | - | $19,993 | 4 | $87,830 | Apr 11 | Artificial Eye | false |
| 63 | Some Came Running | - | - | - | $19,030 | 2 | $28,594 | May 16 | British Film Institute (BFI) | false |
| 64 | Funny Games | - | - | - | $18,070 | 63 | $402,675 | Apr 4 | Tartan | false |
| 65 | You, the Living | - | - | - | $17,921 | 7 | $193,983 | Mar 28 | Artificial Eye | false |
| 66 | Shotgun Stories | - | - | - | $16,682 | 7 | $35,365 | May 23 | Vertigo Films | false |
| 67 | U Me Aur Hum | - | - | - | $13,929 | 46 | $811,670 | Apr 11 | Eros Worldwide | false |
| 68 | U2 3D | - | - | - | $13,693 | 67 | $1,447,732 | Feb 22 | Revolver Entertainment | false |
| 69 | The Ugly Duckling and Me! | - | - | - | $13,274 | 99 | $818,133 | Jul 6 | Eclipse Pictures | false |
| 70 | REC | - | - | - | $10,362 | 70 | $450,650 | Apr 11 | Odeon Sky Filmworks | false |
| 71 | Private Property | - | - | - | $9,839 | 3 | $64,504 | Apr 18 | Soda Pictures | false |
| 72 | The Conformist 2008 Re-release | - | - | - | $9,759 | 6 | $219,923 | Feb 29 | British Film Institute (BFI) | false |
| 73 | 10,000 BC | - | - | - | $8,252 | 431 | $11,349,484 | Mar 14 | Warner Bros. | false |
| 74 | My Blueberry Nights | - | - | - | $7,351 | 69 | $553,574 | Feb 22 | Optimum Releasing | false |
| 75 | Dangerous Parking | - | - | - | $7,067 | 7 | $7,337 | May 23 | Delanic Films | false |
| 76 | The Air I Breathe | - | - | - | $6,312 | 3 | $7,058 | May 16 | Pathé | false |
| 77 | Death Note 2008 Re-release | - | - | - | $6,195 | 1 | $11,665 | Apr 25 | Blue Dolphin Film Distribution | false |
| 78 | Cashback | - | - | - | $6,103 | 4 | $6,103 | May 9 | The Works UK Distribution | false |
| 79 | Vexille | - | - | - | $5,837 | 1 | $6,377 | May 9 | Momentum Pictures | false |
| 80 | The 39 Steps 2008 Re-release | - | - | - | $5,176 | 3 | $51,711 | Apr 11 | Park Circus | false |
| 81 | Still Life | - | - | - | $4,982 | 4 | $75,967 | Feb 1 | British Film Institute (BFI) | false |
| 82 | Flight of the Red Balloon | - | - | - | $4,751 | 6 | $88,650 | Mar 14 | Park Circus | false |
| 83 | One Missed Call | - | - | - | $4,678 | 254 | $2,339,087 | Apr 4 | Warner Bros. | false |
| 84 | Mister Lonely | - | - | - | $4,498 | 3 | $30,795 | Mar 14 | Tartan | false |
| 85 | Garbage Warrior | - | - | - | $4,126 | 2 | $8,844 | May 23 | ICA Films | false |
| 86 | The Water Horse | - | - | - | $3,475 | 438 | $9,501,096 | Feb 8 | Sony Pictures Releasing | false |
| 87 | Winter Soldier | - | - | - | $2,825 | 1 | $2,825 | May 8 | Stoney Road Films | false |
| 88 | The Edge of Heaven | - | - | - | $2,779 | 13 | $279,263 | Feb 22 | Artificial Eye | false |
| 89 | Azur & Asmar: The Princes' Quest | - | - | - | $2,674 | 28 | $70,131 | Feb 8 | Soda Pictures | false |
| 90 | Vantage Point | - | - | - | $2,456 | 352 | $11,552,655 | Mar 7 | Sony Pictures Releasing | false |
| 91 | Tovarisch, I Am Not Dead | - | - | - | $2,397 | 1 | $2,397 | May 2 | - | false |
| 92 | RFK Must Die: The Assassination of Bobby Kennedy | - | - | - | $2,178 | 2 | $2,218 | May 16 | Soda Pictures | false |
| 93 | 4 Months, 3 Weeks and 2 Days | - | - | - | $1,995 | 22 | $589,837 | Jan 4 | Artificial Eye | false |
| 94 | Mouth to Mouth 2008 Re-release | - | - | - | $1,667 | 1 | $1,667 | May 9 | - | false |
| 95 | Stop-Loss | - | - | - | $1,583 | 24 | $30,982 | Apr 25 | Paramount Pictures International | false |
| 96 | The Aerial | - | - | - | $1,522 | 4 | $24,824 | Aug 1 | - | false |
| 97 | I Served the King of England | - | - | - | $1,407 | 1 | $1,407 | May 9 | Arrow Films | false |
| 98 | I'm a Cyborg, But That's OK | - | - | - | $1,218 | 3 | $25,706 | Apr 4 | Tartan | false |
| 99 | Redacted | - | - | - | $1,087 | 6 | $40,329 | Mar 14 | Optimum Releasing | false |
| 100 | Beaufort | - | - | - | $1,049 | 3 | $24,688 | Mar 28 | Trinity Filmed Entertainment | false |
| 101 | In the Valley of Elah | - | - | - | $317 | 216 | $1,734,605 | Jan 25 | Optimum Releasing | false |
| 102 | The Duchess of Langeais | - | - | - | $40 | 2 | $60,661 | Dec 28 | Artificial Eye | false |
| 103 | Under the Bombs | - | - | - | $39 | 2 | $30,867 | Mar 21 | Artificial Eye | false |
