| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Pirates of the Caribbean: At World's End | - | - | - | $165,436 | - | $351,629 | May 25 | Universal Pictures International (UPI) | false |
| 2 | Spider-Man 3 | - | - | - | $140,965 | - | $148,290 | May 4 | - | false |
| 3 | Wild Hogs | - | - | - | $76,819 | - | $162,108 | Apr 27 | - | false |
| 4 | Pathfinder | - | - | - | $59,614 | - | $66,392 | May 11 | - | false |
| 5 | The Reaping | - | - | - | $53,264 | - | $102,168 | Apr 27 | - | false |
| 6 | TMNT | - | - | - | $43,034 | - | $69,473 | May 18 | - | false |
| 7 | Disturbia | - | - | - | $35,985 | - | $42,271 | May 11 | - | false |
| 8 | The Number 23 | - | - | - | $27,579 | - | $46,967 | May 18 | Garsu Pasaulio Irasai | false |
| 9 | Shooter | - | - | - | $21,722 | - | $107,130 | Apr 20 | - | false |
| 10 | Bridge to Terabithia | - | - | - | $20,626 | - | $22,519 | May 4 | - | false |
| 11 | Perfect Stranger | - | - | - | $19,661 | - | $98,658 | Apr 13 | - | false |
| 12 | Mr. Bean's Holiday | - | - | - | $15,932 | - | $384,955 | Mar 30 | - | false |
| 13 | Arthur and the Invisibles | - | - | - | $13,037 | - | $130,719 | Apr 6 | - | false |
| 14 | Because I Said So | - | - | - | $12,933 | - | $29,153 | May 25 | - | false |
| 15 | Next | - | - | - | $11,351 | - | $14,433 | May 18 | - | false |
| 16 | Dark Blue Almost Black | - | - | - | $8,435 | - | $19,162 | May 4 | Planetos Filmai | false |
| 17 | Before Flying Back to Earth | - | - | - | $6,724 | - | $45,968 | Apr 13 | - | false |
| 18 | The Hills Have Eyes 2 | - | - | - | $5,888 | - | $96,990 | Apr 6 | - | false |
| 19 | Sunshine | - | - | - | $4,799 | - | $29,152 | Apr 20 | - | false |
| 20 | I'm Staying | - | - | - | $4,067 | - | $6,969 | Apr 29 | - | false |
| 21 | Odna lyubov na million | - | - | - | $3,200 | - | $3,200 | May 4 | - | false |
| 22 | Nuodemes uzkalbejimas | - | - | - | $3,058 | - | $272,737 | Mar 2 | - | false |
| 23 | The Borgia | - | - | - | $2,856 | - | $7,279 | Apr 27 | - | false |
| 24 | Me and You and Everyone We Know | - | - | - | $2,046 | - | $10,504 | May 25 | - | false |
| 25 | Meet the Robinsons | - | - | - | $1,762 | - | $26,670 | Mar 30 | - | false |
| 26 | Vnuk Gagarina | - | - | - | $1,442 | - | $1,442 | May 11 | - | false |
| 27 | Adam's Apples | - | - | - | $1,391 | - | $34,148 | Feb 9 | Planetos Filmai | false |
| 28 | Norbit | - | - | - | $1,256 | - | $72,082 | Mar 23 | - | false |
| 29 | Music and Lyrics | - | - | - | $893 | - | $49,590 | Mar 23 | - | false |
| 30 | Garfield: A Tail of Two Kitties | - | - | - | $590 | 2 | $358,900 | Jul 28 | Universal Pictures International (UPI) | false |
| 31 | Ice Age 2: The Meltdown | - | - | - | $590 | 3 | $665,174 | Apr 7 | Universal Pictures International (UPI) | false |
| 32 | Paris, Je T'aime | - | - | - | $406 | - | $31,899 | Jan 26 | - | false |
| 33 | Notes on a Scandal | - | - | - | $290 | - | $20,069 | Mar 9 | - | false |
| 34 | Little Miss Sunshine | - | - | - | $255 | - | $13,076 | Jan 5 | - | false |
| 35 | Something Like Happiness | - | - | - | $230 | - | $3,320 | Apr 6 | - | false |
| 36 | Charlotte's Web | - | - | - | $218 | - | $151,930 | Feb 16 | - | false |
| 37 | Captain Alatriste: The Spanish Musketeer | - | - | - | $141 | - | $11,113 | Mar 23 | - | false |
| 38 | Borat | - | - | - | $65 | - | $512,725 | Nov 3 | - | false |
| 39 | Little Children | - | - | - | $46 | - | $27,223 | Feb 16 | - | false |
| 40 | Dreamgirls | - | - | - | $39 | - | $36,200 | Feb 23 | - | false |
| 41 | Smokin' Aces | - | - | - | $37 | - | $33,236 | Mar 16 | - | false |
| 42 | Flushed Away | - | - | - | $32 | - | $310,302 | Dec 8 | - | false |
| 43 | The Good Shepherd | - | - | - | $21 | - | $18,674 | Mar 16 | - | false |
| 44 | Flags of Our Fathers | - | - | - | $13 | - | $14,074 | Feb 23 | - | false |
| 45 | Letters from Iwo Jima | - | - | - | $11 | - | $19,354 | Mar 9 | - | false |
