| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Pirates of the Caribbean: At World's End | - | - | - | $3,779,405 | 172 | $7,999,532 | May 23 | Buena Vista International | false |
| 2 | Spider-Man 3 | - | - | - | $3,485,726 | 148 | $4,113,104 | May 1 | Buena Vista International | false |
| 3 | Wild Hogs | - | - | - | $1,007,995 | 80 | $1,941,721 | Apr 18 | Buena Vista International | false |
| 4 | Mr. Bean's Holiday | - | - | - | $679,221 | 90 | $4,168,842 | Mar 29 | Universal Pictures International (UPI) | false |
| 5 | Fracture | - | - | - | $644,581 | 34 | $1,103,677 | May 9 | Warner Bros. | false |
| 6 | Shooter | - | - | - | $467,579 | 43 | $886,033 | Apr 18 | Universal Pictures International (UPI) | false |
| 7 | Two Days in Paris | - | - | - | $309,439 | 15 | $831,801 | May 16 | Xenix Filmdistribution | false |
| 8 | Zodiac | - | - | - | $276,236 | 33 | $759,987 | May 16 | Warner Bros. | false |
| 9 | Away from Her | - | - | - | $208,328 | 7 | $371,773 | Apr 19 | Ascot Elite Entertainment Group | false |
| 10 | The Lives of Others | - | - | - | $180,552 | 9 | $1,309,293 | Aug 10 | Buena Vista International | false |
| 11 | Goodbye Bafana | - | - | - | $163,284 | 9 | $245,924 | Apr 11 | Filmcoopi Zürich | false |
| 12 | Next | - | - | - | $151,821 | 22 | $620,399 | Apr 26 | Ascot Elite Entertainment Group | false |
| 13 | Perfect Stranger | - | - | - | $144,820 | 42 | $495,834 | Apr 11 | Buena Vista International | false |
| 14 | 300 | - | - | - | $139,906 | 51 | $1,851,658 | Mar 22 | Warner Bros. | false |
| 15 | Four Minutes | - | - | - | $131,937 | 9 | $249,244 | May 10 | Filmcoopi Zürich | false |
| 16 | Bruno Manser - Laki Penan | - | - | - | $126,378 | 13 | $249,930 | Apr 5 | Filmcoopi Zürich | false |
| 17 | Blades of Glory | - | - | - | $119,179 | 29 | $134,101 | May 9 | Universal Pictures International (UPI) | false |
| 18 | Hunting and Gathering | - | - | - | $103,429 | 19 | $1,003,733 | Mar 21 | Pathé | false |
| 19 | Little Children | - | - | - | $94,611 | 8 | $208,051 | Apr 26 | Warner Bros. | false |
| 20 | Wild Chicks in Love | - | - | - | $91,763 | 14 | $265,523 | Apr 5 | Rialto Distribution | false |
| 21 | Two Times Lotte | - | - | - | $88,560 | 20 | $123,149 | May 16 | Warner Bros. | false |
| 22 | Sunshine | - | - | - | $70,955 | 36 | $278,003 | Apr 11 | 20th Century Fox International | false |
| 23 | La Vie En Rose | - | - | - | $67,347 | 15 | $1,778,039 | Feb 14 | Pathé | false |
| 24 | Miss Potter | - | - | - | $64,149 | 10 | $369,855 | Mar 22 | Ascot Elite Entertainment Group | false |
| 25 | My Best Friend | - | - | - | $61,135 | 4 | $521,989 | Dec 20 | Frenetic Films | false |
| 26 | A Prairie Home Companion | - | - | - | $56,690 | 4 | $217,546 | Dec 6 | Filmcoopi Zürich | false |
| 27 | Curse of the Golden Flower | - | - | - | $53,821 | 4 | $141,446 | Mar 14 | Pathé | false |
| 28 | The Diving Bell and the Butterfly | - | - | - | $53,603 | 8 | $118,160 | May 23 | Pathé | false |
| 29 | Irina Palm | - | - | - | $53,275 | 14 | $652,102 | May 9 | Filmcoopi Zürich | false |
| 30 | The Number 23 | - | - | - | $48,133 | 10 | $396,609 | Mar 22 | Warner Bros. | false |
| 31 | Music and Lyrics | - | - | - | $24,898 | 28 | $1,973,598 | Feb 23 | Warner Bros. | false |
| 32 | Late Bloomers | - | - | - | $12,618 | 12 | $6,939,992 | Oct 5 | Buena Vista International | false |
