| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Spider-Man 3 | - | - | - | $4,239,368 | 96 | $5,412,600 | May 1 | Sony Pictures Releasing | false |
| 2 | Pirates of the Caribbean: At World's End | - | - | - | $3,662,163 | 160 | $10,029,123 | May 23 | Buena Vista International | false |
| 3 | Fracture | - | - | - | $1,055,610 | 43 | $1,833,299 | May 9 | Kinepolis Film Distribution (KFD) | false |
| 4 | Mr. Bean's Holiday | - | - | - | $835,274 | 56 | $3,211,472 | Apr 4 | Universal Pictures International (UPI) | false |
| 5 | Next | - | - | - | $654,718 | 43 | $1,051,097 | Apr 25 | Kinepolis Film Distribution (KFD) | false |
| 6 | The Good Shepherd | - | - | - | $573,789 | 56 | $1,092,693 | Apr 18 | Benelux Film Distributors | false |
| 7 | The Hills Have Eyes 2 | - | - | - | $365,070 | 30 | $510,751 | May 16 | 20th Century Fox International | false |
| 8 | Wild Hogs | - | - | - | $356,810 | 47 | $942,886 | Apr 11 | Buena Vista International | false |
| 9 | The Messengers | - | - | - | $335,867 | 19 | $445,629 | May 2 | Benelux Film Distributors | false |
| 10 | The Price to Pay | - | - | - | $268,005 | 17 | $486,743 | Apr 18 | Cinéart | false |
| 11 | Happily N'Ever After | - | - | - | $256,274 | 63 | $659,401 | Apr 4 | Belga Films | false |
| 12 | Shooter | - | - | - | $229,297 | 28 | $698,117 | Apr 11 | Universal Pictures International (UPI) | false |
| 13 | Bordertown | - | - | - | $225,049 | 31 | $321,084 | Apr 25 | Belga Films | false |
| 14 | Perfect Stranger | - | - | - | $205,390 | 32 | $682,459 | Apr 11 | Sony Pictures Releasing | false |
| 15 | The Last Mimzy | - | - | - | $191,775 | 25 | $269,702 | May 16 | Belga Films | false |
| 16 | The Reaping | - | - | - | $160,872 | 19 | $347,966 | Apr 18 | Warner Bros. | false |
| 17 | Hunting and Gathering | - | - | - | $158,025 | 17 | $780,710 | Mar 21 | Alternative Films | false |
| 18 | The Hitcher | - | - | - | $139,351 | 19 | $152,572 | May 9 | Kinepolis Film Distribution (KFD) | false |
| 19 | Blades of Glory | - | - | - | $131,871 | 22 | $138,482 | May 9 | Universal Pictures International (UPI) | false |
| 20 | Alpha Dog | - | - | - | $123,822 | 11 | $202,375 | Apr 25 | Paradiso Entertainment | false |
| 21 | The Lives of Others | - | - | - | $109,615 | 18 | $1,432,152 | Jan 31 | ABC Distribution | false |
| 22 | Bridge to Terabithia | - | - | - | $107,291 | 34 | $480,070 | Mar 28 | Kinepolis Film Distribution (KFD) | false |
| 23 | Norbit | - | - | - | $100,900 | 33 | $1,516,765 | Mar 21 | Universal Pictures International (UPI) | false |
| 24 | To Walk Again | - | - | - | $94,686 | 12 | $139,692 | Apr 25 | Kinepolis Film Distribution (KFD) | false |
| 25 | Curse of the Golden Flower | - | - | - | $86,584 | 20 | $270,913 | Apr 11 | Kinepolis Film Distribution (KFD) | false |
| 26 | 300 | - | - | - | $83,417 | 46 | $2,216,126 | Mar 21 | Warner Bros. | false |
| 27 | Infamous | - | - | - | $81,324 | 11 | $129,650 | May 16 | Benelux Film Distributors | false |
| 28 | Music and Lyrics | - | - | - | $80,271 | 51 | $1,338,843 | Mar 28 | Warner Bros. | false |
| 29 | Could This Be Love? | - | - | - | $74,249 | 20 | $76,124 | May 2 | Cinéart | false |
| 30 | Irina Palm | - | - | - | $70,857 | 7 | $144,552 | Apr 18 | Paradiso Entertainment | false |
| 31 | The Departed | - | - | - | $68,956 | 85 | $3,799,810 | Dec 27 | Warner Bros. | false |
| 32 | Sunshine | - | - | - | $65,357 | 45 | $373,324 | Apr 11 | 20th Century Fox International | false |
| 33 | Cages | - | - | - | $61,075 | 6 | $71,280 | May 9 | Cinéart | false |
| 34 | Barnyard | - | - | - | $60,210 | 31 | $717,262 | Feb 21 | Universal Pictures International (UPI) | false |
| 35 | Charlotte's Web | - | - | - | $45,546 | 58 | $1,170,513 | Feb 7 | Universal Pictures International (UPI) | false |
| 36 | Still Life | - | - | - | $45,488 | 4 | $57,482 | May 9 | Cinéart | false |
| 37 | The Dead Girl | - | - | - | $42,555 | 8 | $101,229 | May 23 | Kinepolis Film Distribution (KFD) | false |
| 38 | TMNT | - | - | - | $39,652 | 42 | $212,119 | Mar 28 | Warner Bros. | false |
| 39 | Goodbye Bafana | - | - | - | $37,916 | 14 | $119,818 | Apr 11 | Cinéart | false |
| 40 | With Friends Like These | - | - | - | $36,461 | 14 | $324,497 | Mar 21 | Kinepolis Film Distribution (KFD) | false |
| 41 | The Host | - | - | - | $35,171 | 4 | $48,394 | May 2 | A-Film Distribution | false |
| 42 | Pur week-end | - | - | - | $34,749 | 17 | $36,180 | May 2 | - | false |
| 43 | The Namesake | - | - | - | $32,964 | 5 | $47,225 | May 16 | 20th Century Fox International | false |
| 44 | Please Don't Go | - | - | - | $29,332 | 11 | $43,808 | Apr 25 | Les Films de l'Elysée | false |
| 45 | Fragments of Antonin | - | - | - | $27,325 | 7 | $27,765 | May 16 | Les Films de l'Elysée | false |
| 46 | Love Songs | - | - | - | $26,009 | 8 | $39,783 | May 23 | Les Films de l'Elysée | false |
| 47 | Tales from Earthsea | - | - | - | $25,906 | 6 | $33,632 | May 16 | Paradiso Entertainment | false |
| 48 | The Diving Bell and the Butterfly | - | - | - | $23,618 | 5 | $86,189 | May 23 | Alternative Films | false |
| 49 | Epic Movie | - | - | - | $20,101 | 40 | $801,897 | Mar 28 | 20th Century Fox International | false |
| 50 | Stomp the Yard | - | - | - | $19,210 | 3 | $57,710 | May 23 | Sony Pictures Releasing | false |
| 51 | The Missing Star | - | - | - | $18,557 | 6 | $83,247 | May 23 | Cinéart | false |
| 52 | The Number 23 | - | - | - | $17,762 | 23 | $846,937 | Feb 28 | Paradiso Entertainment | false |
| 53 | Our Country | - | - | - | $15,303 | 4 | $18,863 | May 2 | Cinéart | false |
| 54 | My Son | - | - | - | $12,143 | 5 | $12,418 | May 9 | ABC Distribution | false |
| 55 | The Witnesses | - | - | - | $9,646 | 13 | $114,319 | Mar 28 | Benelux Film Distributors | false |
| 56 | Crank | - | - | - | $9,555 | 10 | $215,397 | Mar 14 | Paradiso Entertainment | false |
| 57 | Flyboys | - | - | - | $8,486 | 12 | $8,486 | May 16 | - | false |
| 58 | Kid Power | - | - | - | $8,147 | 16 | $146,658 | Apr 4 | Les Films de l'Elysée | false |
| 59 | Gone for a Dance | - | - | - | $7,762 | 9 | $20,984 | Apr 25 | Cinéart | false |
| 60 | The Italian | - | - | - | $7,608 | 5 | $7,716 | May 23 | Jekino | false |
| 61 | Conversations with Other Women | - | - | - | $7,548 | 1 | $7,548 | May 16 | Les Films de l'Elysée | false |
| 62 | It's a Boy Girl Thing | - | - | - | $6,650 | 12 | $196,081 | Feb 14 | Kinepolis Film Distribution (KFD) | false |
| 63 | Two Times Lotte | - | - | - | $6,236 | 2 | $17,134 | May 18 | Warner Bros. | false |
| 64 | Pars: Operation Cherry | - | - | - | $4,385 | 4 | $12,195 | Apr 25 | - | false |
| 65 | Breaking and Entering | - | - | - | $4,014 | 21 | $292,750 | Mar 21 | Buena Vista International | false |
| 66 | David Susskind - Sois un mensch, mon fils! | - | - | - | $4,007 | 3 | $4,470 | May 2 | - | false |
| 67 | Our Daily Bread | - | - | - | $3,703 | 4 | $35,796 | Feb 7 | Benelux Film Distributors | false |
| 68 | Ghost Rider | - | - | - | $3,406 | 30 | $944,785 | Feb 21 | Sony Pictures Releasing | false |
| 69 | Angel | - | - | - | $2,613 | 21 | $109,752 | Mar 14 | ABC Distribution | false |
| 70 | Dennis P. | - | - | - | $1,801 | 2 | $2,152 | May 2 | Kinepolis Film Distribution (KFD) | false |
| 71 | Babel | - | - | - | $1,619 | 36 | $2,577,292 | Nov 15 | Belga Films | false |
| 72 | Salvador | - | - | - | $1,007 | 1 | $78,331 | Jan 10 | Benelux Film Distributors | false |
| 73 | On the Ropes | - | - | - | $928 | 1 | $2,050 | May 2 | Les Films de l'Elysée | false |
| 74 | Los hijos de la noche | - | - | - | $573 | 1 | $573 | May 9 | - | false |
| 75 | El custodio 2007 Re-release | - | - | - | $183 | 1 | $894 | Apr 25 | ABC Distribution | false |
| 76 | Zozo 2007 Re-release | - | - | - | $52 | 1 | $52 | May 9 | Jekino | false |
