| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Spider-Man 3 | - | - | - | $18,108,726 | 500 | $19,658,418 | - | Sony Pictures Releasing | false |
| 2 | Pirates of the Caribbean: At World's End | - | - | - | $12,368,651 | 606 | $29,085,288 | May 24 | Buena Vista International | false |
| 3 | Because I Said So | - | - | - | $2,656,744 | 167 | $3,204,284 | May 3 | Magna Pacific | false |
| 4 | Zodiac | - | - | - | $2,022,592 | 182 | $3,745,009 | - | Roadshow Entertainment | false |
| 5 | Georgia Rule | - | - | - | $1,811,287 | 169 | $2,645,461 | May 10 | Hoyts Distribution | false |
| 6 | 28 Weeks Later | - | - | - | $1,693,620 | 161 | $2,068,055 | May 10 | 20th Century Fox International | false |
| 7 | Shooter | - | - | - | $1,601,430 | 188 | $4,494,310 | Apr 19 | Paramount Pictures International | false |
| 8 | The History Boys | - | - | - | $864,385 | 55 | $1,147,946 | May 3 | 20th Century Fox International | false |
| 9 | Perfect Stranger | - | - | - | $811,609 | 208 | $2,728,780 | Apr 19 | Sony Pictures Releasing | false |
| 10 | Breach | - | - | - | $775,845 | 92 | $1,746,153 | May 17 | Rialto Distribution | false |
| 11 | 300 | - | - | - | $680,904 | 338 | $12,304,031 | Apr 5 | Warner Bros. | false |
| 12 | Lucky You | - | - | - | $673,742 | 145 | $767,258 | May 10 | Roadshow Films | false |
| 13 | The Number 23 | - | - | - | $635,202 | 111 | $1,353,169 | Apr 25 | Roadshow Films | false |
| 14 | The Lives of Others | - | - | - | $530,608 | 34 | $2,402,435 | Mar 29 | Hopscotch Films | false |
| 15 | Paris, Je T'aime | - | - | - | $476,731 | 31 | $1,324,279 | Apr 19 | Madman Entertainment | false |
| 16 | Curse of the Golden Flower | - | - | - | $473,163 | 64 | $874,176 | Apr 25 | Paramount Pictures International | false |
| 17 | Noise | - | - | - | $407,761 | 24 | $737,867 | May 3 | Madman Entertainment | false |
| 18 | Disturbia | - | - | - | $368,191 | 211 | $3,953,867 | Apr 12 | Paramount Pictures International | false |
| 19 | Mr. Bean's Holiday | - | - | - | $356,127 | 347 | $14,032,488 | Mar 29 | Paramount Pictures International | false |
| 20 | Becoming Jane | - | - | - | $335,454 | 113 | $2,919,312 | Mar 29 | Dendy Films | false |
| 21 | Reno 911!: Miami | - | - | - | $305,395 | 88 | $362,882 | May 17 | Paramount Pictures International | false |
| 22 | Stomp the Yard | - | - | - | $297,920 | 119 | $3,263,915 | Apr 12 | Sony Pictures Releasing | false |
| 23 | Wild Hogs | - | - | - | $241,956 | 291 | $14,062,601 | Mar 8 | Buena Vista International | false |
| 24 | The Italian | - | - | - | $240,788 | 17 | $880,844 | Apr 25 | Sharmill Films | false |
| 25 | Meet the Robinsons | - | - | - | $191,753 | 318 | $6,967,594 | Mar 29 | Buena Vista International | false |
| 26 | Half Nelson | - | - | - | $170,864 | 17 | $482,025 | Apr 25 | Palace Films | false |
| 27 | As It Is in Heaven | - | - | - | $142,128 | 25 | $3,065,532 | Aug 3 | Rialto Distribution | false |
| 28 | My Best Friend | - | - | - | $110,460 | 21 | $530,190 | May 24 | Hopscotch Films | false |
| 29 | The Reaping | - | - | - | $110,370 | 136 | $1,039,470 | Apr 19 | Roadshow Films | false |
| 30 | Off the Grid | - | - | - | $97,187 | 3 | $218,499 | May 24 | Warren Miller Entertainment | false |
| 31 | The Science of Sleep | - | - | - | $57,558 | 17 | $263,200 | May 3 | Rialto Distribution | false |
| 32 | Shootout at Lokhandwala | - | - | - | $26,591 | 7 | $26,591 | May 24 | MG Distribution | false |
| 33 | The Page Turner | - | - | - | $26,003 | 8 | $191,476 | May 10 | Potential Films | false |
| 34 | Infamous | - | - | - | $23,169 | 5 | $133,581 | May 17 | Icon Film Distribution Australia | false |
| 35 | Deliver Us from Evil | - | - | - | $18,388 | 9 | $78,338 | May 17 | Roadshow Films | false |
| 36 | Into Great Silence | - | - | - | $15,997 | 5 | $71,386 | May 17 | Dendy Films | false |
| 37 | Life in a Metro | - | - | - | $13,671 | 10 | $45,900 | May 11 | - | false |
