| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Spider-Man 3 | - | - | - | $3,964,871 | 202 | $4,584,691 | May 3 | Sony Pictures Releasing | false |
| 2 | Pirates of the Caribbean: At World's End | - | - | - | $2,248,584 | 258 | $4,889,474 | May 24 | Buena Vista International | false |
| 3 | The Lives of Others | - | - | - | $446,479 | 25 | $996,495 | Apr 19 | Alfa Films | false |
| 4 | Fracture | - | - | - | $394,232 | 82 | $1,211,338 | May 17 | Distribution Company | false |
| 5 | La Vie En Rose | - | - | - | $318,565 | 23 | $498,543 | May 10 | Alfa Films | false |
| 6 | The Messengers | - | - | - | $245,736 | 29 | $342,257 | Apr 26 | Alfa Films | false |
| 7 | Perfect Stranger | - | - | - | $232,773 | 50 | $742,891 | Apr 12 | Sony Pictures Releasing | false |
| 8 | 300 | - | - | - | $200,050 | 86 | $4,587,738 | Mar 29 | Warner Bros. | false |
| 9 | Meet the Robinsons | - | - | - | $180,441 | 108 | $1,800,959 | Mar 29 | Buena Vista International | false |
| 10 | Mr. Bean's Holiday | - | - | - | $161,225 | 16 | $260,585 | May 10 | United International Pictures | false |
| 11 | Zodiac | - | - | - | $160,881 | 21 | $328,706 | May 17 | Warner Bros. | false |
| 12 | Disturbia | - | - | - | $158,059 | 30 | $395,827 | Apr 19 | United International Pictures | false |
| 13 | The Number 23 | - | - | - | $139,649 | 27 | $782,187 | Mar 22 | Distribution Company | false |
| 14 | Happily N'Ever After | - | - | - | $123,321 | 34 | $284,226 | Apr 19 | Distribution Company | false |
| 15 | The Other | - | - | - | $105,706 | 14 | $118,075 | May 10 | Distribution Company | false |
| 16 | Trust the Man | - | - | - | $88,973 | 21 | $204,696 | Apr 19 | Pachamama Cine | false |
| 17 | Fur: An Imaginary Portrait of Diane Arbus | - | - | - | $88,125 | 13 | $103,096 | May 3 | Distribution Company | false |
| 18 | 12:08 East of Bucharest | - | - | - | $78,051 | 11 | $86,363 | May 3 | Zeta Films | false |
| 19 | Wild Hogs | - | - | - | $75,441 | 41 | $315,709 | Apr 12 | Buena Vista International | false |
| 20 | Music and Lyrics | - | - | - | $68,570 | 31 | $835,350 | Mar 15 | Warner Bros. | false |
| 21 | The Mistress of Spices | - | - | - | $52,569 | 9 | $69,327 | May 17 | Pachamama Cine | false |
| 22 | TMNT | - | - | - | $42,103 | 51 | $310,837 | Apr 5 | Distribution Company | false |
| 23 | Sunshine | - | - | - | $40,091 | 20 | $125,346 | Apr 19 | 20th Century Fox International | false |
| 24 | Time | - | - | - | $36,569 | 11 | $64,436 | May 24 | Distribution Company | false |
| 25 | Shooter | - | - | - | $36,361 | 30 | $256,871 | Apr 5 | United International Pictures | false |
| 26 | Pathfinder | - | - | - | $34,089 | 15 | $199,981 | Mar 22 | 20th Century Fox International | false |
| 27 | Notes on a Scandal | - | - | - | $33,387 | 20 | $230,937 | Mar 8 | 20th Century Fox International | false |
| 28 | Tres de corazones | - | - | - | $31,799 | 28 | $87,574 | Apr 26 | Distribution Company | false |
| 29 | The Reaping | - | - | - | $31,039 | 33 | $300,515 | Apr 5 | Warner Bros. | false |
| 30 | Epic Movie | - | - | - | $28,419 | 20 | $207,991 | Mar 29 | 20th Century Fox International | false |
| 31 | Scoop | - | - | - | $23,264 | 23 | $389,462 | Mar 22 | CDI Films | false |
| 32 | 7 Years | - | - | - | $22,744 | 5 | $48,878 | Apr 26 | Impacto Cine | false |
| 33 | The Queen | - | - | - | $22,312 | 34 | $848,709 | Feb 22 | Distribution Company | false |
| 34 | Paris, Je T'aime | - | - | - | $18,503 | 15 | $295,107 | Mar 15 | Impacto Cine | false |
| 35 | A Wrecked Filmmaker | - | - | - | $17,465 | 9 | $17,235 | May 3 | Primer Plano Film Group | false |
| 36 | El amor y la ciudad | - | - | - | $16,681 | 16 | $69,951 | Apr 19 | Primer Plano Film Group | false |
| 37 | Cocalero | - | - | - | $15,519 | 5 | $22,255 | May 17 | Primer Plano Film Group | false |
| 38 | The Best of Youth 2007 Re-release | - | - | - | $14,696 | 3 | $106,720 | May 17 | IFA | false |
| 39 | Flushed Away | - | - | - | $14,314 | 90 | $1,612,596 | Jan 4 | United International Pictures | false |
| 40 | Hoodwinked! | - | - | - | $14,280 | 44 | $822,570 | Feb 8 | Alfa Films | false |
| 41 | Night at the Museum | - | - | - | $13,996 | 92 | $3,216,799 | Jan 18 | 20th Century Fox International | false |
| 42 | The Wicker Man | - | - | - | $9,966 | 20 | $231,143 | Mar 8 | Distribution Company | false |
| 43 | Crank | - | - | - | $9,863 | 27 | $165,939 | Mar 8 | Alfa Films | false |
| 44 | Kept and Dreamless | - | - | - | $9,619 | 13 | $18,616 | Apr 26 | Primer Plano Film Group | false |
| 45 | Ghost Rider | - | - | - | $9,137 | 38 | $568,079 | Mar 15 | Sony Pictures Releasing | false |
| 46 | Who Says It's Easy? | - | - | - | $8,722 | 54 | $1,265,601 | Feb 8 | Primer Plano Film Group | false |
| 47 | Arthur and the Invisibles | - | - | - | $8,666 | 43 | $121,283 | Apr 5 | Alfa Films | false |
| 48 | Captain Alatriste: The Spanish Musketeer | - | - | - | $8,456 | 15 | $44,482 | Apr 5 | 20th Century Fox International | false |
| 49 | Apocalypto | - | - | - | $8,068 | 30 | $862,406 | Feb 1 | 20th Century Fox International | false |
| 50 | Babel | - | - | - | $7,263 | 47 | $1,738,658 | Jan 18 | United International Pictures | false |
| 51 | Blood Diamond | - | - | - | $6,262 | 46 | $895,324 | Feb 8 | Warner Bros. | false |
| 52 | The Education of Fairies | - | - | - | $5,152 | 18 | $87,467 | Mar 29 | Buena Vista International | false |
| 53 | Stranger Than Fiction | - | - | - | $4,744 | 14 | $181,346 | Mar 8 | Sony Pictures Releasing | false |
| 54 | Changing Times | - | - | - | $4,208 | 3 | $68,629 | Mar 22 | Alfa Films | false |
| 55 | The U.S. vs. John Lennon | - | - | - | $3,972 | 3 | $9,255 | Apr 26 | Distribution Company | false |
| 56 | Argentina Beat | - | - | - | $3,696 | 4 | $3,696 | May 3 | Primer Plano Film Group | false |
| 57 | Letters from Iwo Jima | - | - | - | $3,252 | 14 | $307,431 | Feb 15 | Warner Bros. | false |
| 58 | The Aerial | - | - | - | $3,052 | 5 | $16,831 | Apr 19 | Pachamama Cine | false |
| 59 | Rocky Balboa | - | - | - | $2,795 | 38 | $421,458 | Mar 1 | 20th Century Fox International | false |
| 60 | Norbit | - | - | - | $2,211 | 30 | $244,838 | Mar 8 | United International Pictures | false |
| 61 | Mothers | - | - | - | $1,814 | 2 | $2,294 | May 3 | Primer Plano Film Group | false |
| 62 | The Last King of Scotland | - | - | - | $1,534 | 14 | $163,322 | Feb 15 | 20th Century Fox International | false |
| 63 | C.R.A.Z.Y. | - | - | - | $1,213 | 7 | $49,324 | Mar 15 | Alfa Films | false |
| 64 | City in Heat | - | - | - | $997 | 3 | $32,697 | Mar 22 | Alfa Films | false |
| 65 | Funny Ha Ha 2007 Re-release | - | - | - | $801 | 1 | $2,689 | Apr 19 | 791 Cine | false |
| 66 | Time to Leave | - | - | - | $483 | 12 | $62,078 | Mar 1 | Alfa Films | false |
| 67 | Flags of Our Fathers | - | - | - | $116 | 15 | $208,156 | Jan 25 | Warner Bros. | false |
