| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Spider-Man 3 | - | - | - | $2,225,325 | 37 | $2,360,566 | May 3 | - | false |
| 2 | Pirates of the Caribbean: At World's End | - | - | - | $980,584 | 38 | $1,716,451 | May 24 | - | false |
| 3 | Bridge to Terabithia | - | - | - | $222,372 | 19 | $243,879 | May 10 | - | false |
| 4 | Disturbia | - | - | - | $214,333 | 19 | $357,260 | Apr 26 | - | false |
| 5 | The Hills Have Eyes 2 | - | - | - | $202,148 | 13 | $202,148 | May 17 | - | false |
| 6 | Reno 911!: Miami | - | - | - | $193,631 | 19 | $193,631 | May 10 | - | false |
| 7 | The Breed | - | - | - | $176,511 | 17 | $182,480 | May 17 | - | false |
| 8 | Hot Fuzz | - | - | - | $155,782 | 19 | $164,509 | May 17 | - | false |
| 9 | Are We Done Yet? | - | - | - | $121,067 | 16 | $237,152 | Apr 26 | - | false |
| 10 | Until Death | - | - | - | $109,348 | 10 | $109,348 | May 17 | - | false |
| 11 | Wild Hogs | - | - | - | $108,031 | 19 | $525,513 | Apr 19 | - | false |
| 12 | Flyboys | - | - | - | $107,945 | 19 | $107,945 | May 10 | - | false |
| 13 | Taxi 4 | - | - | - | $100,228 | 18 | $258,925 | Apr 26 | - | false |
| 14 | Shooter | - | - | - | $90,993 | 19 | $680,272 | Apr 12 | - | false |
| 15 | Mr. Bean's Holiday | - | - | - | $85,478 | 21 | $1,328,061 | Apr 5 | - | false |
| 16 | The Good Shepherd | - | - | - | $50,716 | 27 | $165,024 | Apr 19 | - | false |
| 17 | Death Train | - | - | - | $47,458 | 15 | $107,822 | Apr 26 | - | false |
| 18 | The Trail | - | - | - | $36,948 | 7 | $36,948 | May 3 | - | false |
| 19 | ABDO Mawasem | - | - | - | $18,748 | 10 | $18,748 | May 3 | - | false |
| 20 | Blades of Glory | - | - | - | $14,789 | 19 | $92,196 | Apr 19 | - | false |
| 21 | The Reaping | - | - | - | $14,603 | 19 | $202,533 | Apr 19 | - | false |
| 22 | Zay Al Hawa | - | - | - | $13,575 | 7 | $13,575 | May 17 | - | false |
| 23 | Happy Feet | - | - | - | $8,397 | 1 | $605,597 | Dec 21 | - | false |
| 24 | Provoked | - | - | - | $6,127 | 13 | $135,209 | Apr 5 | - | false |
| 25 | Death of a President | - | - | - | $5,583 | 2 | $5,583 | May 3 | - | false |
| 26 | Hannibal Rising | - | - | - | $4,058 | 2 | $310,814 | Mar 22 | - | false |
| 27 | Happily N'Ever After | - | - | - | $2,999 | 1 | $135,443 | Mar 22 | - | false |
| 28 | The Namesake | - | - | - | $770 | 3 | $84,426 | Mar 22 | - | false |
| 29 | Norbit | - | - | - | $335 | 4 | $870,065 | Mar 15 | - | false |
