| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Star Wars: Episode III - Revenge of the Sith | - | - | - | $2,469,463 | 115 | $4,704,603 | May 19 | 20th Century Fox International | false |
| 2 | Kingdom of Heaven | - | - | - | $2,409,574 | 104 | $2,980,011 | May 5 | 20th Century Fox International | false |
| 3 | The Pacifier | - | - | - | $1,708,855 | 68 | $2,145,061 | Apr 28 | Buena Vista International | false |
| 4 | The Interpreter | - | - | - | $618,613 | 56 | $1,533,973 | Apr 14 | United International Pictures | false |
| 5 | Pooh's Heffalump Movie | - | - | - | $510,033 | 86 | $657,017 | Apr 28 | Buena Vista International | false |
| 6 | Robots | - | - | - | $489,030 | 171 | $1,789,452 | Mar 24 | 20th Century Fox International | false |
| 7 | The Wedding Date | - | - | - | $398,364 | 50 | $627,474 | - | - | false |
| 8 | xXx: State of the Union | - | - | - | $377,290 | 64 | $503,525 | Apr 28 | Sony Pictures Releasing | false |
| 9 | Hitch | - | - | - | $341,295 | 94 | $4,160,196 | Mar 10 | United International Pictures | false |
| 10 | White Noise | - | - | - | $234,069 | 62 | $825,782 | Apr 14 | Independent Films | false |
| 11 | Son of the Mask | - | - | - | $221,469 | 70 | $348,974 | Apr 21 | RCV Film Distribution | false |
| 12 | Boogeyman | - | - | - | $163,622 | 50 | $402,990 | Apr 21 | Independent Films | false |
| 13 | Hostage | - | - | - | $138,360 | 63 | $655,054 | May 26 | Independent Films | false |
| 14 | The SpongeBob SquarePants Movie | - | - | - | $123,120 | 145 | $3,255,175 | Feb 3 | United International Pictures | false |
| 15 | Be Cool | - | - | - | $120,913 | 44 | $911,777 | Mar 31 | 20th Century Fox International | false |
| 16 | House of Wax | - | - | - | $111,993 | 40 | $419,797 | May 26 | Warner Bros. | false |
| 17 | The Consequences of Love | - | - | - | $72,828 | 12 | $183,326 | May 12 | Cinemien | false |
| 18 | The Assassination of Richard Nixon | - | - | - | $67,224 | 12 | $116,993 | May 12 | Independent Films | false |
| 19 | What the #$*! Do We (K)now!? 2005 Re-release | - | - | - | $66,730 | 12 | $146,301 | May 12 | Cinemien | false |
| 20 | Miss Congeniality 2: Armed & Fabulous | - | - | - | $54,490 | 102 | $1,418,123 | Mar 24 | Warner Bros. | false |
| 21 | The Sea Inside | - | - | - | $52,755 | 20 | $584,883 | Jan 27 | A-Film Distribution | false |
| 22 | Nobody Knows | - | - | - | $47,677 | 9 | $101,087 | Apr 14 | Bright Angel Distribution | false |
| 23 | Hotel Rwanda | - | - | - | $47,400 | 24 | $368,305 | Mar 17 | RCV Film Distribution | false |
| 24 | Million Dollar Baby | - | - | - | $39,593 | 38 | $1,414,538 | Feb 27 | A-Film Distribution | false |
| 25 | Sideways | - | - | - | $37,118 | 19 | $570,873 | Feb 17 | 20th Century Fox International | false |
| 26 | Dear Wendy | - | - | - | $36,003 | 14 | $56,763 | May 19 | A-Film Distribution | false |
| 27 | Racing Stripes | - | - | - | $19,642 | 82 | $815,839 | Feb 3 | Independent Films | false |
| 28 | My Summer of Love | - | - | - | $13,053 | 5 | $40,845 | Apr 21 | A-Film Distribution | false |
| 29 | Without a Paddle | - | - | - | $8,532 | 7 | $50,280 | May 12 | United International Pictures | false |
