| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Star Wars: Episode III - Revenge of the Sith | - | - | - | $49,299,165 | 490 | $51,745,549 | May 19 | 20th Century Fox International | false |
| 2 | Kingdom of Heaven | - | - | - | $12,787,221 | 450 | $14,535,907 | May 6 | 20th Century Fox International | false |
| 3 | The Hitchhiker's Guide to the Galaxy | - | - | - | $12,086,690 | 465 | $20,349,279 | Apr 29 | Buena Vista International | false |
| 4 | Monster-in-Law | - | - | - | $8,410,120 | 381 | $12,018,392 | May 13 | Entertainment Film Distributors | false |
| 5 | The Wedding Date | - | - | - | $3,334,188 | 301 | $7,577,974 | Apr 22 | Entertainment Film Distributors | false |
| 6 | xXx: State of the Union | - | - | - | $3,331,311 | 398 | $5,073,836 | Apr 29 | Sony Pictures Releasing | false |
| 7 | The Interpreter | - | - | - | $3,317,934 | 370 | $13,726,376 | Apr 15 | United International Pictures | false |
| 8 | The Amityville Horror | - | - | - | $2,073,933 | 346 | $9,597,259 | Apr 15 | 20th Century Fox International | false |
| 9 | Guess Who | - | - | - | $1,609,526 | 348 | $4,283,766 | Apr 22 | 20th Century Fox International | false |
| 10 | House of Wax | - | - | - | $1,395,211 | 304 | $5,361,953 | May 27 | Warner Bros. | false |
| 11 | The Pacifier | - | - | - | $1,327,557 | 351 | $7,932,070 | May 27 | Buena Vista International | false |
| 12 | Hitch | - | - | - | $1,039,385 | 449 | $33,371,422 | Mar 4 | Sony Pictures Releasing | false |
| 13 | The Jacket | - | - | - | $971,649 | 130 | $1,157,069 | May 13 | Warner Bros. | false |
| 14 | A Good Woman | - | - | - | $863,209 | 105 | $1,277,790 | May 13 | Vertigo Films | false |
| 15 | Valiant | - | - | - | $638,376 | 454 | $15,921,564 | Mar 25 | Entertainment Film Distributors | false |
| 16 | Waqt: The Race Against Time | - | - | - | $602,172 | 36 | $1,580,552 | Apr 15 | Eros Worldwide | false |
| 17 | Millions | - | - | - | $534,428 | 256 | $2,740,140 | May 27 | Pathé | false |
| 18 | Seed of Chucky | - | - | - | $512,869 | 92 | $575,011 | May 13 | Momentum Pictures | false |
| 19 | Ong-Bak: The Thai Warrior | - | - | - | $498,846 | 86 | $585,655 | May 13 | Contender Entertainment Group | false |
| 20 | It's All Gone Pete Tong | - | - | - | $476,387 | 282 | $1,347,044 | May 27 | Redbus Film Distribution | false |
| 21 | Bunty Aur Babli | - | - | - | $272,913 | 30 | $994,968 | May 27 | Yash Raj Films | false |
| 22 | Jo Bole So Nihaal | - | - | - | $223,516 | 21 | $223,516 | May 13 | - | false |
| 23 | Kaal | - | - | - | $172,264 | 21 | $364,686 | Apr 29 | Yash Raj Films | false |
| 24 | Friday Night Lights | - | - | - | $168,695 | 50 | $168,695 | May 13 | United International Pictures | false |
| 25 | Mysterious Skin | - | - | - | $168,111 | 15 | $376,832 | May 20 | Tartan | false |
| 26 | Be Cool | - | - | - | $152,955 | 336 | $7,978,177 | Apr 1 | - | false |
| 27 | Beauty Shop | - | - | - | $109,797 | 107 | $723,915 | Apr 22 | Verve Pictures | false |
| 28 | Mean Creek | - | - | - | $98,686 | 19 | $156,377 | Apr 29 | Tartan | false |
| 29 | The Consequences of Love | - | - | - | $87,839 | 14 | $598,258 | May 27 | Artificial Eye | false |
| 30 | Palindromes | - | - | - | $51,484 | 15 | $51,484 | May 6 | Tartan | false |
| 31 | Miss Congeniality 2: Armed & Fabulous | - | - | - | $39,975 | 380 | $10,121,539 | Mar 25 | Warner Bros. | false |
| 32 | Clifford's Really Big Movie | - | - | - | $34,890 | 50 | $310,397 | Apr 29 | - | false |
| 33 | Only Human | - | - | - | $33,122 | 13 | $124,848 | May 20 | Verve Pictures | false |
