Domestic Box Office For May 2001
| Rank | Release | Gross | Max Th | Opening | % of Total | Open Th | Open | Close | Distributor |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Shrek | $268,200,241 | 3,715 | $42,347,760 | 15.8% | 3,587 | May 16 | Dec 6 | DreamWorks Distribution |
| 2 | The Mummy Returns | $202,019,785 | 3,553 | $68,139,035 | 33.7% | 3,401 | May 4 | - | Universal Pictures |
| 3 | Pearl Harbor | $198,542,554 | 3,255 | $59,078,912 | 29.8% | 3,214 | May 25 | - | Walt Disney Studios Motion Pictures |
| 4 | Moulin Rouge! | $57,386,607 | 2,283 | $167,540 | 0.3% | 2 | May 18 | - | 20th Century Fox |
| 5 | A Knight's Tale | $56,569,702 | 2,980 | $16,511,391 | 29.2% | 2,980 | May 11 | - | Sony Pictures Releasing |
| 6 | Angel Eyes | $24,174,218 | 2,407 | $9,225,575 | 38.2% | 2,375 | May 18 | - | Warner Bros. |
| 7 | Under the Sand | $1,452,698 | 25 | $32,657 | 2.2% | 2 | May 4 | - | WinStar Cinema |
| 8 | Startup.com | $1,283,356 | 35 | $16,118 | 1.3% | 1 | May 11 | - | Artisan Entertainment |
| 9 | The Road Home | $1,280,490 | 37 | - | - | - | May 25 | - | Sony Pictures Classics |
| 10 | Sordid Lives | $1,111,273 | 8 | - | - | - | May 11 | Apr 20 | Regent Releasing |
| 11 | The Man Who Cried | $747,092 | 28 | $93,455 | 12.5% | 11 | May 25 | - | Focus Features |
| 12 | Bread and Roses | $533,479 | 39 | $49,662 | 9.3% | 34 | May 11 | Jul 12 | Lionsgate |
| 13 | About Adam | $159,668 | 11 | $33,300 | 20.9% | 5 | May 11 | May 31 | Miramax |
| 14 | The Trumpet of the Swan | $102,202 | 125 | $102,202 | 100% | 125 | May 11 | - | Sony Pictures Releasing |
| 15 | Eureka | $49,388 | - | - | - | - | May 4 | May 24 | Shooting Gallery |
| 16 | Pavilion of Women | $36,992 | 9 | $16,368 | 44.2% | 9 | May 4 | May 24 | Focus Features |
| 17 | The King Is Alive | $17,929 | 6 | $17,929 | 100% | 6 | May 11 | - | IFC Films |
| 18 | Fast Food Fast Women | $17,131 | 2 | $17,131 | 100% | 2 | May 18 | - | Lot 47 Films |
| 19 | Nora | $15,120 | 8 | $12,297 | 81.3% | 8 | May 4 | - | Andora Pictures International |
| 20 | Time and Tide | $10,770 | 1 | $10,770 | 100% | 1 | May 4 | - | Sony Pictures Releasing |
| 21 | The Young Girl and the Monsoon | $9,186 | - | - | - | - | May 4 | May 17 | Artistic License |
| 22 | Bloody Angels | $6,509 | - | - | - | - | May 25 | - | USA Films |
