| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Max Th | Opening | % of Total
| Open Th | Open | Close | Distributor
| Estimated
|
|---|
| 1 | Lethal Weapon 3 | - | - | - | $144,731,527 | 2,568 | $33,243,086 | 23% | 2,510 | May 15 | - | Warner Bros. | false |
| 2 | Sister Act | - | - | - | $139,605,150 | 2,087 | $11,894,587 | 8.5% | 1,430 | May 29 | - | Walt Disney Studios Motion Pictures | false |
| 3 | Far and Away | - | - | - | $58,883,840 | 1,885 | $10,194,520 | 17.3% | 1,583 | May 22 | - | Universal Pictures | false |
| 4 | Alien³ | - | - | - | $55,473,545 | 2,227 | $19,449,867 | 35.1% | 2,227 | May 22 | - | 20th Century Fox | false |
| 5 | Encino Man | - | - | - | $40,693,477 | 2,090 | $9,866,120 | 24.2% | 2,050 | May 22 | - | Walt Disney Studios Motion Pictures | false |
| 6 | Folks! | - | - | - | $6,132,924 | 1,402 | $2,177,518 | 35.5% | 1,402 | May 1 | - | 20th Century Fox | false |
| 7 | Split Second | - | - | - | $5,430,822 | 1,085 | $2,250,000 | 41.4% | 1,085 | May 1 | - | InterStar Releasing | false |
| 8 | K2 | - | - | - | $3,106,559 | 350 | $930,655 | 30% | 350 | May 1 | - | Paramount Pictures | false |
| 9 | CrissCross | - | - | - | $3,052,738 | 449 | $1,041,264 | 34.1% | 449 | May 8 | - | Metro-Goldwyn-Mayer (MGM) | false |
| 10 | Night on Earth | - | - | - | $2,015,810 | 40 | $34,039 | 1.7% | 2 | May 1 | Sep 24 | Fine Line Features | false |
| 11 | Poison Ivy | - | - | - | $1,829,804 | 20 | $119,840 | 6.5% | 20 | May 8 | - | New Line Cinema | false |
| 12 | The Waterdance | - | - | - | $1,723,319 | 60 | $138,313 | 8% | 33 | May 15 | - | The Samuel Goldwyn Company | false |
| 13 | One False Move | - | - | - | $1,543,112 | 32 | $44,545 | 2.9% | 5 | May 8 | Oct 1 | IRS Media | false |
| 14 | Leaving Normal | - | - | - | $1,514,114 | 362 | $474,220 | 31.3% | 362 | May 1 | - | Universal Pictures | false |
| 15 | Europa | - | - | - | $1,007,001 | 1 | $21,447 | 2.1% | 1 | May 22 | - | Miramax | false |
| 16 | Cabeza de Vaca | - | - | - | $789,127 | 11 | $5,960 | 0.8% | 1 | May 15 | - | Concorde Pictures | false |
| 17 | Turtle Beach | - | - | - | $778,535 | 727 | $350,951 | 45.1% | 727 | May 1 | - | Warner Bros. | false |
| 18 | Wild Orchid II: Two Shades of Blue | - | - | - | $573,904 | 266 | $323,288 | 56.3% | 266 | May 8 | - | Triumph Releasing Corporation | false |
| 19 | Incident at Oglala | - | - | - | $536,848 | 12 | $19,070 | 3.6% | 3 | May 8 | - | Miramax | false |
| 20 | The Adjuster | - | - | - | $396,573 | 18 | $10,686 | 2.7% | 1 | May 29 | Sep 10 | Orion Classics | false |
| 21 | Monster in a Box | - | - | - | $311,245 | - | - | - | - | May 15 | Aug 20 | Fine Line Features | false |
| 22 | Big Girls Don't Cry... They Get Even | - | - | - | $271,327 | - | - | - | - | May 8 | Jun 4 | New Line Cinema | false |
| 23 | Cold Heaven | - | - | - | $99,219 | - | - | - | - | May 29 | - | Hemdale | false |
| 24 | Diary of a Hitman | - | - | - | $31,815 | 18 | $17,388 | 54.7% | 18 | May 1 | May 7 | Vision International | false |
| 25 | Rubin and Ed | - | - | - | $15,675 | 2 | $4,131 | 26.4% | 1 | May 15 | - | IRS Media | false |
| 26 | The Vagrant | - | - | - | $5,900 | 8 | $4,300 | 72.9% | 8 | May 15 | May 21 | Metro-Goldwyn-Mayer (MGM) | false |
| 27 | Who Shot Pat? | - | - | - | $2,343 | 1 | $2,343 | 100% | 1 | May 1 | May 3 | Castle Hill Productions | false |
