| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Max Th | Opening | % of Total
| Open Th | Open | Close | Distributor
| Estimated
|
|---|
| 1 | Indiana Jones and the Last Crusade | - | - | - | $197,171,806 | 2,327 | $29,355,021 | 14.9% | 2,327 | May 24 | - | Paramount Pictures | false |
| 2 | See No Evil, Hear No Evil | - | - | - | $46,908,987 | 1,686 | $7,098,741 | 15.1% | 1,677 | May 12 | - | TriStar Pictures | false |
| 3 | Road House | - | - | - | $30,050,028 | 1,935 | $5,957,656 | 19.8% | 1,927 | May 19 | - | United Artists | false |
| 4 | Pink Cadillac | - | - | - | $12,143,484 | 1,993 | $4,408,593 | 36.3% | 1,993 | May 26 | - | Warner Bros. | false |
| 5 | Listen to Me | - | - | - | $4,299,023 | 1,306 | $1,789,759 | 41.6% | 1,306 | May 5 | - | Columbia Pictures | false |
| 6 | Earth Girls Are Easy | - | - | - | $3,916,303 | 317 | $892,742 | 22.8% | 317 | May 12 | - | Vestron Pictures | false |
| 7 | Fright Night Part 2 | - | - | - | $2,983,784 | 161 | $548,231 | 18.4% | 148 | May 19 | - | New Century | false |
| 8 | How I Got Into College | - | - | - | $1,642,239 | 743 | $651,850 | 39.7% | 743 | May 19 | - | Twentieth Century Fox | false |
| 9 | Miracle Mile | - | - | - | $1,145,404 | 143 | $341,401 | 29.8% | 143 | May 19 | - | Hemdale | false |
| 10 | Getting It Right | - | - | - | $960,385 | 44 | $73,159 | 7.6% | 44 | May 5 | Oct 5 | Management Company Entertainment Group (MCEG) | false |
| 11 | The Wizard of Oz 1989 Re-release | - | - | - | $612,300 | - | - | - | - | May 19 | - | Metro-Goldwyn-Mayer (MGM) | false |
| 12 | The Rainbow | - | - | - | $444,055 | - | - | - | - | May 5 | Jun 29 | Vestron Pictures | false |
| 13 | How to Get Ahead in Advertising | - | - | - | $418,053 | - | - | - | - | May 5 | Jul 6 | Warner Bros. | false |
| 14 | The Rachel Papers | - | - | - | $201,468 | - | - | - | - | May 12 | - | United Artists | false |
| 15 | The Return of Swamp Thing | - | - | - | $192,816 | - | - | - | - | May 12 | - | Millimeter Films | false |
| 16 | For Queen & Country | - | - | - | $191,051 | 33 | $62,771 | 32.9% | 33 | May 19 | - | Atlantic Releasing Corporation | false |
| 17 | Night Visitor | - | - | - | $166,635 | - | - | - | - | May 12 | - | Metro-Goldwyn-Mayer (MGM) | false |
| 18 | Signs of Life | - | - | - | $95,836 | - | - | - | - | May 5 | - | Avenue Pictures Productions | false |
