| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Max Th | Opening | % of Total
| Open Th | Open | Close | Distributor
| Estimated
|
|---|
| 1 | Escort in Love | - | - | - | $11,471,250 | 485 | $2,667,461 | 23.3% | 472 | Mar 16 | - | 01 Distribution | false |
| 2 | Rango | - | - | - | $6,831,092 | 408 | $2,735,421 | 40% | 408 | Mar 11 | - | Universal Pictures International (UPI) | false |
| 3 | The Rite | - | - | - | $5,133,279 | 314 | $1,709,238 | 33.3% | 314 | Mar 11 | - | Warner Bros. | false |
| 4 | Amici miei - Come tutto ebbe inizio | - | - | - | $4,828,128 | 473 | $1,623,014 | 33.6% | 473 | Mar 16 | - | Filmauro | false |
| 5 | La vita facile | - | - | - | $3,801,152 | 324 | $1,165,700 | 30.7% | 324 | Mar 4 | - | Medusa Distribuzione | false |
| 6 | Dylan Dog: Dead of Night | - | - | - | $3,447,524 | 250 | $1,121,158 | 32.5% | 250 | Mar 16 | - | Moviemax | false |
| 7 | The Fighter | - | - | - | $3,200,200 | 279 | $1,096,210 | 34.3% | 270 | Mar 4 | - | Eagle Pictures | false |
| 8 | No Strings Attached | - | - | - | $2,369,436 | 258 | $974,215 | 41.1% | 258 | Mar 25 | - | Universal Pictures International (UPI) | false |
| 9 | Gnomeo & Juliet | - | - | - | $2,205,926 | 277 | $711,574 | 32.3% | 277 | Mar 16 | - | Walt Disney Pictures | false |
| 10 | Piranha 3D | - | - | - | $2,025,594 | 268 | $952,002 | 47% | 268 | Mar 4 | - | BIM Distribuzione | false |
| 11 | The Kids Are All Right | - | - | - | $1,908,701 | 124 | $579,760 | 30.4% | 124 | Mar 11 | - | Lucky Red | false |
| 12 | StreetDance 2 | - | - | - | $1,827,218 | 227 | $672,351 | 36.8% | 227 | Mar 16 | - | Eagle Pictures | false |
| 13 | The Jewel | - | - | - | $1,368,586 | 175 | $447,707 | 32.7% | 175 | Mar 4 | - | BIM Distribuzione | false |
| 14 | Sucker Punch | - | - | - | $1,349,817 | 279 | $705,944 | 52.3% | 279 | Mar 25 | - | Warner Bros. | false |
| 15 | Frozen | - | - | - | $837,592 | 102 | $366,081 | 43.7% | 102 | Mar 25 | - | - | false |
| 16 | All at Sea | - | - | - | $626,012 | 177 | $435,468 | 69.6% | 177 | Mar 11 | - | 01 Distribution | false |
| 17 | Never Let Me Go | - | - | - | $590,123 | 99 | $240,037 | 40.7% | 99 | Mar 25 | - | 20th Century Fox International | false |
| 18 | The Last Fashion Show | - | - | - | $565,895 | 325 | $364,868 | 64.5% | 325 | Mar 25 | - | Medusa Distribuzione | false |
| 19 | Silvio Forever | - | - | - | $532,916 | 104 | $256,979 | 48.2% | 104 | Mar 25 | - | Lucky Red | false |
| 20 | Sorelle mai | - | - | - | $429,931 | 41 | $106,395 | 24.7% | 41 | Mar 16 | - | Teodora Film | false |
| 21 | Una cella in due | - | - | - | $353,508 | 81 | $167,875 | 47.5% | 81 | Mar 4 | - | - | false |
| 22 | Hard Times | - | - | - | $148,498 | 38 | $89,270 | 60.1% | 38 | Mar 11 | - | - | false |
| 23 | The Return of Don Camillo | - | - | - | $127,840 | 14 | $108,335 | 84.7% | 14 | Mar 11 | - | - | false |
| 24 | Succo di marca | - | - | - | $118,144 | 3 | $25,306 | 21.4% | 3 | Mar 11 | - | - | false |
| 25 | Morning Glory | - | - | - | $88,408 | 39 | $52,317 | 59.2% | 39 | Mar 4 | - | Universal Pictures International (UPI) | false |
| 26 | Beyond | - | - | - | $85,359 | 13 | $24,790 | 29% | 13 | Mar 16 | - | Sacher Distribuzione | false |
| 27 | On Tour | - | - | - | $83,959 | 11 | $14,451 | 17.2% | 10 | Mar 16 | - | - | false |
| 28 | Easy A | - | - | - | $82,427 | 32 | $51,967 | 63% | 32 | Mar 4 | - | Sony Pictures Releasing | false |
| 29 | Le stelle inquiete | - | - | - | $64,635 | 6 | $20,991 | 32.5% | 6 | Mar 11 | - | Bolero Film | false |
| 30 | The House by the Medlar Tree | - | - | - | $61,010 | 22 | $990 | 1.6% | 1 | Mar 4 | - | - | false |
| 31 | With Love... from the Age of Reason | - | - | - | $52,264 | 51 | $52,264 | 100% | 51 | Mar 11 | - | - | false |
| 32 | Gangor | - | - | - | $51,032 | 11 | $24,004 | 47% | 11 | Mar 11 | - | - | false |
| 33 | Boogie Woogie | - | - | - | $22,144 | 15 | $22,144 | 100% | 15 | Mar 4 | - | Eagle Pictures | false |
| 34 | Space Dogs | - | - | - | $20,729 | 47 | $20,729 | 100% | 47 | Mar 25 | - | One Movie | false |
| 35 | Tra due donne | - | - | - | $15,825 | 1 | $1,401 | 8.9% | 1 | Mar 4 | - | Istituto Luce | false |
| 36 | Ramona and Beezus | - | - | - | $6,203 | 10 | $6,203 | 100% | 10 | Mar 11 | - | 20th Century Fox International | false |
