| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Alice in Wonderland | - | - | - | $3,251,466 | 96 | $3,525,009 | Mar 4 | Walt Disney Pictures | false |
| 2 | It's Complicated | - | - | - | $1,214,361 | 70 | $1,436,315 | Mar 4 | United International Pictures | false |
| 3 | Shutter Island | - | - | - | $767,153 | 62 | $1,232,057 | Feb 25 | Zon Lusomundo Audiovisuais | false |
| 4 | How to Train Your Dragon | - | - | - | $724,758 | 76 | $2,548,807 | Mar 25 | Zon Lusomundo Audiovisuais | false |
| 5 | The Book of Eli | - | - | - | $395,130 | 33 | $552,478 | Mar 11 | Sony Pictures Releasing | false |
| 6 | Edge of Darkness | - | - | - | $321,741 | 44 | $511,220 | Mar 18 | Prisvídeo | false |
| 7 | Remember Me | - | - | - | $289,522 | 38 | $451,557 | Mar 18 | Zon Lusomundo Audiovisuais | false |
| 8 | The Princess and the Frog | - | - | - | $268,872 | 68 | $1,532,519 | Feb 4 | Walt Disney Pictures | false |
| 9 | The Wolfman | - | - | - | $263,603 | 65 | $930,826 | Feb 18 | Zon Lusomundo Audiovisuais | false |
| 10 | Solomon Kane | - | - | - | $254,294 | 37 | $374,783 | Mar 18 | Zon Lusomundo Audiovisuais | false |
| 11 | The Blind Side | - | - | - | $205,173 | 29 | $712,584 | Mar 25 | Warner Bros. | false |
| 12 | The Spy Next Door 2010 Re-release | - | - | - | $169,565 | 22 | $298,025 | Feb 25 | Prisvídeo | false |
| 13 | The Lovely Bones | - | - | - | $154,525 | 25 | $164,735 | Mar 11 | Zon Lusomundo Audiovisuais | false |
| 14 | Cloudy with a Chance of Meatballs | - | - | - | $131,314 | 55 | $926,477 | Feb 11 | Sony Pictures Releasing | false |
| 15 | Dear John | - | - | - | $131,282 | 20 | $381,018 | Mar 25 | Castello Lopes Multimédia | false |
| 16 | Whatever Works | - | - | - | $125,434 | 20 | $608,676 | Feb 4 | Zon Lusomundo Audiovisuais | false |
| 17 | Invictus | - | - | - | $124,191 | 44 | $1,249,560 | Jan 28 | Warner Bros. | false |
| 18 | The Hurt Locker | - | - | - | $99,143 | 10 | $231,335 | Sep 17 | Zon Lusomundo Audiovisuais | false |
| 19 | A Single Man | - | - | - | $98,080 | 7 | $229,706 | Feb 18 | Prisvídeo | false |
| 20 | Precious | - | - | - | $80,617 | 13 | $283,991 | Feb 11 | - | false |
| 21 | The Imaginarium of Doctor Parnassus | - | - | - | $79,080 | 17 | $224,228 | Mar 25 | Prisvídeo | false |
| 22 | Avatar | - | - | - | $54,353 | 96 | $10,109,275 | Dec 17 | 20th Century Fox International | false |
| 23 | Percy Jackson & the Olympians: The Lightning Thief | - | - | - | $52,415 | 29 | $415,031 | Feb 11 | Castello Lopes Multimédia | false |
| 24 | Everybody's Fine | - | - | - | $47,961 | 20 | $111,775 | Mar 25 | Zon Lusomundo Audiovisuais | false |
| 25 | Up in the Air | - | - | - | $47,914 | 56 | $1,371,763 | Jan 21 | Zon Lusomundo Audiovisuais | false |
| 26 | Valentine's Day | - | - | - | $41,026 | 40 | $691,806 | Feb 11 | Warner Bros. | false |
| 27 | The Men Who Stare at Goats | - | - | - | $28,431 | 32 | $544,549 | Feb 4 | Prisvídeo | false |
| 28 | An Education | - | - | - | $26,923 | 8 | $79,220 | Feb 18 | Zon Lusomundo Audiovisuais | false |
| 29 | A Serious Man | - | - | - | $24,622 | 4 | $67,419 | Feb 18 | Castello Lopes Multimédia | false |
| 30 | Alvin and the Chipmunks: The Squeakquel | - | - | - | $22,653 | 40 | $1,365,989 | Dec 24 | 20th Century Fox International | false |
| 31 | The Messenger | - | - | - | $12,910 | 6 | $19,324 | Feb 25 | Zon Lusomundo Audiovisuais | false |
| 32 | The Girl Who Played with Fire | - | - | - | $12,565 | 7 | $25,319 | Mar 25 | Zon Lusomundo Audiovisuais | false |
| 33 | Nine | - | - | - | $7,954 | 30 | $581,581 | Jan 14 | Castello Lopes Multimédia | false |
| 34 | The Cove | - | - | - | $3,320 | 4 | $5,835 | Feb 25 | Prisvídeo | false |
| 35 | My One and Only | - | - | - | $1,824 | 6 | $28,258 | Feb 11 | Zon Lusomundo Audiovisuais | false |
| 36 | The Code | - | - | - | $1,264 | 22 | $188,994 | Jan 14 | Zon Lusomundo Audiovisuais | false |
| 37 | Antichrist | - | - | - | $1,154 | 9 | $72,842 | Jan 28 | Prisvídeo | false |
| 38 | Tony Manero | - | - | - | $999 | 1 | $3,600 | Mar 11 | - | false |
| 39 | Did You Hear About the Morgans? | - | - | - | $371 | 45 | $711,370 | Jan 7 | Sony Pictures Releasing | false |
