| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Alice in Wonderland | - | - | - | $27,990,816 | 448 | $25,414,578 | Mar 4 | Walt Disney Pictures | false |
| 2 | The Blind Side | - | - | - | $7,465,392 | 226 | $12,273,902 | Feb 25 | Roadshow Films | false |
| 3 | Avatar | - | - | - | $6,705,676 | 590 | $103,866,237 | - | 20th Century Fox International | false |
| 4 | Green Zone | - | - | - | $5,006,270 | 245 | $5,969,528 | Mar 11 | Universal Pictures International (UPI) | false |
| 5 | Dear John | - | - | - | $4,093,597 | 196 | $4,164,640 | Mar 4 | Roadshow Films | false |
| 6 | Shutter Island | - | - | - | $3,892,547 | 250 | $9,515,631 | Feb 18 | Paramount Pictures International | false |
| 7 | How to Train Your Dragon | - | - | - | $3,736,265 | 368 | $16,883,185 | - | Paramount Pictures International | false |
| 8 | The Hurt Locker | - | - | - | $3,250,498 | 76 | $5,226,567 | Feb 18 | Roadshow Films | false |
| 9 | The Bounty Hunter | - | - | - | $3,101,854 | 204 | $4,409,434 | Mar 18 | Sony Pictures Releasing | false |
| 10 | Valentine's Day | - | - | - | $1,666,836 | 373 | $14,478,430 | Feb 11 | Warner Bros. | false |
| 11 | Cop Out | - | - | - | $1,340,084 | 349 | $1,455,162 | Mar 18 | Warner Bros. | false |
| 12 | The Men Who Stare at Goats | - | - | - | $1,282,464 | 58 | $1,326,574 | Mar 4 | Sony Pictures Releasing | false |
| 13 | Remember Me | - | - | - | $1,208,978 | 174 | $1,216,554 | Mar 11 | Hoyts Distribution | false |
| 14 | The Girl with the Dragon Tattoo | - | - | - | $946,353 | 90 | $4,849,540 | Mar 25 | Rialto Distribution | false |
| 15 | Percy Jackson & the Olympians: The Lightning Thief | - | - | - | $908,945 | 229 | $4,567,200 | Feb 11 | 20th Century Fox International | false |
| 16 | A Single Man | - | - | - | $904,835 | 30 | $1,380,617 | - | Icon Film Distribution Australia | false |
| 17 | The Rebound | - | - | - | $882,937 | 190 | $882,937 | Mar 18 | Roadshow Films | false |
| 18 | Nanny McPhee Returns | - | - | - | $618,869 | 261 | $7,354,806 | Apr 1 | Universal Pictures International (UPI) | false |
| 19 | From Paris with Love | - | - | - | $591,769 | 157 | $1,743,558 | Feb 18 | Hoyts Distribution | false |
| 20 | Up in the Air | - | - | - | $517,489 | 191 | $7,481,902 | Jan 14 | Paramount Pictures International | false |
| 21 | Crazy Heart | - | - | - | $457,599 | 76 | $873,124 | Feb 18 | 20th Century Fox International | false |
| 22 | Precious | - | - | - | $376,698 | 50 | $1,223,232 | Feb 4 | Icon Film Distribution Australia | false |
| 23 | Bran Nue Dae | - | - | - | $370,990 | 234 | $6,698,962 | Jan 14 | Roadshow Films | false |
| 24 | The Wolfman | - | - | - | $341,615 | 246 | $3,774,847 | Feb 11 | Universal Pictures International (UPI) | false |
| 25 | Invictus | - | - | - | $321,060 | 262 | $6,432,362 | Jan 21 | Warner Bros. | false |
| 26 | It's Complicated | - | - | - | $310,329 | 304 | $14,187,266 | Jan 7 | Universal Pictures International (UPI) | false |
| 27 | Brothers | - | - | - | $218,142 | 22 | $218,142 | Mar 18 | Roadshow Films | false |
| 28 | The Spy Next Door 2010 Re-release | - | - | - | $217,640 | 139 | $1,885,876 | Mar 25 | Roadshow Films | false |
| 29 | Tooth Fairy | - | - | - | $178,958 | 243 | $9,475,680 | Jan 14 | 20th Century Fox International | false |
| 30 | My One and Only | - | - | - | $98,419 | 24 | $98,419 | Mar 11 | Hopscotch Films | false |
| 31 | The Last Station 2010 Re-release | - | - | - | $64,509 | 50 | $1,040,696 | Apr 1 | Becker Film Group | false |
| 32 | Cirque du Freak: The Vampire's Assistant | - | - | - | $59,271 | 41 | $59,271 | Mar 11 | Universal Pictures International (UPI) | false |
| 33 | The Lovely Bones | - | - | - | $45,230 | 230 | $6,089,234 | Dec 24 | Paramount Pictures International | false |
| 34 | Law Abiding Citizen | - | - | - | $43,300 | 194 | $4,479,603 | Jan 28 | Roadshow Films | false |
| 35 | Atithi Tum Kab Jaoge? | - | - | - | $20,171 | 5 | $20,171 | Mar 4 | Saini Enterprises | false |
| 36 | Separation City | - | - | - | $13,875 | 15 | $13,875 | Mar 4 | Hoyts Distribution | false |
| 37 | Five Minutes of Heaven | - | - | - | $6,192 | 5 | $6,192 | Mar 18 | Madman Entertainment | false |
| 38 | Going Vertical: The Shortboard Revolution | - | - | - | $3,617 | 14 | $3,617 | Mar 25 | - | false |
| 39 | Little Ashes | - | - | - | $3,166 | 3 | $3,166 | Mar 25 | Kojo Pictures | false |
| 40 | Lad Gaya Pecha | - | - | - | $2,719 | 3 | $2,719 | Mar 25 | Eros Worldwide | false |
