| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Bedtime Stories | - | - | - | $412,912 | 36 | $1,019,509 | Feb 19 | Walt Disney Pictures | false |
| 2 | Slumdog Millionaire | - | - | - | $338,302 | 21 | $764,404 | Feb 19 | Bazuca Films | false |
| 3 | Valkyrie | - | - | - | $210,727 | 43 | $788,657 | Feb 12 | 20th Century Fox International | false |
| 4 | Watchmen | - | - | - | $193,679 | 36 | $214,235 | Mar 5 | United International Pictures | false |
| 5 | Changeling | - | - | - | $163,973 | 33 | $260,517 | Mar 12 | United International Pictures | false |
| 6 | Underworld: Rise of the Lycans | - | - | - | $143,649 | 31 | $316,294 | Mar 19 | Sony Pictures Releasing | false |
| 7 | The Curious Case of Benjamin Button | - | - | - | $142,808 | 36 | $1,109,721 | Jan 22 | Warner Bros. | false |
| 8 | Coraline | - | - | - | $133,321 | 26 | $332,484 | Feb 5 | United International Pictures | false |
| 9 | Jonas Brothers: The 3D Concert Experience | - | - | - | $117,892 | 9 | $126,592 | Mar 5 | Walt Disney Pictures | false |
| 10 | Gran Torino | - | - | - | $113,895 | 15 | $356,118 | Mar 19 | Warner Bros. | false |
| 11 | Impy's Island | - | - | - | $102,270 | 16 | $117,488 | Mar 5 | Bazuca Films | false |
| 12 | Yes Man | - | - | - | $93,175 | 43 | $929,148 | Jan 15 | Warner Bros. | false |
| 13 | He's Just Not That Into You | - | - | - | $88,812 | 22 | $279,930 | Feb 12 | Warner Bros. | false |
| 14 | Friday the 13th | - | - | - | $83,193 | 22 | $270,539 | Feb 12 | United International Pictures | false |
| 15 | Doubt | - | - | - | $76,037 | 7 | $133,548 | Feb 26 | Walt Disney Pictures | false |
| 16 | Bolt | - | - | - | $69,798 | 62 | $1,788,695 | Dec 25 | Walt Disney Pictures | false |
| 17 | Righteous Kill | - | - | - | $65,678 | 18 | $75,329 | Mar 5 | CDI Films | false |
| 18 | Twilight | - | - | - | $50,258 | 56 | $1,290,455 | Jan 1 | Bazuca Films | false |
| 19 | Hotel for Dogs | - | - | - | $39,048 | 23 | $269,095 | Jan 22 | United International Pictures | false |
| 20 | Seven Pounds | - | - | - | $37,173 | 15 | $95,209 | Feb 19 | Sony Pictures Releasing | false |
| 21 | The Bank Job | - | - | - | $34,562 | 12 | $51,184 | Feb 26 | Transeuropa | false |
| 22 | Inkheart | - | - | - | $29,790 | 45 | $369,600 | Feb 5 | Warner Bros. | false |
| 23 | The Duchess | - | - | - | $28,053 | 11 | $75,042 | Feb 19 | United International Pictures | false |
| 24 | Confessions of a Shopaholic | - | - | - | $26,874 | 21 | $106,491 | Mar 26 | Walt Disney Pictures | false |
| 25 | Descendents | - | - | - | $23,478 | 21 | $30,775 | Mar 19 | - | false |
| 26 | The Boy in the Striped Pajamas | - | - | - | $22,929 | 14 | $259,677 | Jan 15 | Walt Disney Pictures | false |
| 27 | The Strangers | - | - | - | $22,722 | 13 | $115,005 | Jan 22 | Bazuca Films | false |
| 28 | Beverly Hills Chihuahua | - | - | - | $20,470 | 38 | $579,028 | Jan 8 | Walt Disney Pictures | false |
| 29 | The Tale of Despereaux | - | - | - | $19,815 | 33 | $158,946 | Jan 29 | United International Pictures | false |
| 30 | Death Defying Acts | - | - | - | $16,280 | 12 | $16,280 | Mar 12 | Transeuropa | false |
| 31 | Che: Part One | - | - | - | $12,459 | 17 | $128,625 | Jan 29 | Bazuca Films | false |
| 32 | Flawless | - | - | - | $12,108 | 10 | $25,274 | Feb 26 | Bazuca Films | false |
| 33 | Reincarnation 2009 Re-release | - | - | - | $11,203 | 7 | $68,087 | Mar 26 | Andes Films | false |
| 34 | Deception | - | - | - | $10,820 | 8 | $13,500 | Mar 19 | Bazuca Films | false |
| 35 | Milk | - | - | - | $9,555 | 6 | $41,028 | Mar 26 | United International Pictures | false |
| 36 | Family Hero | - | - | - | $7,387 | 3 | $29,101 | Feb 12 | Andes Films | false |
| 37 | Planet Terror | - | - | - | $6,811 | 10 | $16,907 | Mar 26 | Bazuca Films | false |
| 38 | Rudo y Cursi | - | - | - | $5,779 | 31 | $17,159 | Feb 26 | United International Pictures | false |
| 39 | Quarantine | - | - | - | $4,355 | 28 | $188,281 | Jan 29 | Sony Pictures Releasing | false |
| 40 | Four Minutes | - | - | - | $2,263 | 2 | $3,099 | Mar 26 | Transeuropa | false |
| 41 | The Spirit | - | - | - | $1,147 | 10 | $22,575 | Jan 22 | Sony Pictures Releasing | false |
| 42 | The Women | - | - | - | $1,107 | 13 | $15,557 | Feb 19 | CDI Films | false |
| 43 | The Pink Panther 2 | - | - | - | $550 | 28 | $76,734 | Feb 5 | Sony Pictures Releasing | false |
| 44 | Bride Wars | - | - | - | $342 | 28 | $146,672 | Jan 29 | 20th Century Fox International | false |
| 45 | The Bottle | - | - | - | $180 | 7 | $5,615 | Feb 26 | Los Filmes de la Arcadia | false |
| 46 | Dan in Real Life | - | - | - | $109 | 16 | $96,830 | Dec 11 | Bazuca Films | false |
