| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | 10,000 BC | - | - | - | $1,010,050 | 39 | $1,222,724 | Mar 6 | Warner Bros. | false |
| 2 | Alvin and the Chipmunks | - | - | - | $517,080 | 35 | $791,700 | Dec 20 | 20th Century Fox International | false |
| 3 | Horton Hears a Who! | - | - | - | $414,998 | 41 | $629,280 | Mar 13 | 20th Century Fox International | false |
| 4 | 31 Minutos, La Película | - | - | - | $286,427 | 38 | $1,065,000 | Mar 27 | MC Film Dagitim | false |
| 5 | One Missed Call | - | - | - | $256,573 | 20 | $281,062 | Feb 28 | Warner Bros. | false |
| 6 | American Gangster | - | - | - | $244,310 | 32 | $254,400 | Feb 28 | United International Pictures | false |
| 7 | No Country for Old Men | - | - | - | $228,410 | 11 | $381,610 | Feb 14 | United International Pictures | false |
| 8 | Mirageman | - | - | - | $215,861 | 29 | $390,003 | Mar 20 | Bazuca Films | false |
| 9 | The Water Horse | - | - | - | $207,247 | 26 | $600,376 | Feb 7 | Sony Pictures Releasing | false |
| 10 | The Game Plan | - | - | - | $201,969 | 22 | $943,428 | Jan 17 | Walt Disney Pictures | false |
| 11 | The Bucket List | - | - | - | $169,423 | 19 | $518,715 | Jan 31 | Warner Bros. | false |
| 12 | The Spiderwick Chronicles | - | - | - | $167,126 | 34 | $439,982 | Mar 20 | United International Pictures | false |
| 13 | Juno | - | - | - | $163,016 | 15 | $244,333 | Feb 21 | Bazuca Films | false |
| 14 | P.S. I Love You | - | - | - | $158,575 | 19 | $307,491 | Feb 14 | Bazuca Films | false |
| 15 | Sweeney Todd: The Demon Barber of Fleet Street | - | - | - | $137,442 | 18 | $492,673 | Feb 7 | Warner Bros. | false |
| 16 | In the Valley of Elah | - | - | - | $134,801 | 15 | $179,931 | Mar 13 | Bazuca Films | false |
| 17 | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | - | - | - | $127,075 | 1 | $169,878 | Feb 28 | Walt Disney Pictures | false |
| 18 | Atonement | - | - | - | $123,835 | 14 | $271,072 | Feb 14 | United International Pictures | false |
| 19 | There Will Be Blood | - | - | - | $117,269 | 14 | $193,863 | Feb 21 | Walt Disney Pictures | false |
| 20 | Jumper | - | - | - | $115,243 | 40 | $394,341 | Mar 27 | 20th Century Fox International | false |
| 21 | Cloverfield | - | - | - | $80,922 | 28 | $416,602 | Feb 7 | United International Pictures | false |
| 22 | I Am Legend | - | - | - | $64,848 | 40 | $1,294,576 | Jan 17 | Warner Bros. | false |
| 23 | The Hitcher | - | - | - | $57,426 | 14 | $57,426 | Feb 28 | Bazuca Films | false |
| 24 | Enchanted | - | - | - | $52,782 | 40 | $1,426,461 | Dec 13 | Walt Disney Pictures | false |
| 25 | Noah's Ark | - | - | - | $50,541 | 16 | $95,569 | Feb 21 | Walt Disney Pictures | false |
| 26 | National Treasure: Book of Secrets | - | - | - | $39,364 | 43 | $1,033,173 | Dec 27 | Walt Disney Pictures | false |
| 27 | Halloween | - | - | - | $25,801 | 11 | $26,232 | Mar 13 | Transeuropa | false |
| 28 | 27 Dresses | - | - | - | $25,399 | 25 | $191,242 | Feb 7 | 20th Century Fox International | false |
| 29 | Love in the Time of Cholera | - | - | - | $24,365 | 27 | $383,805 | Jan 17 | 20th Century Fox International | false |
| 30 | Aliens vs. Predator: Requiem | - | - | - | $20,573 | 33 | $452,162 | Jan 24 | 20th Century Fox International | false |
| 31 | 3:10 to Yuma | - | - | - | $19,802 | 18 | $20,956 | Mar 6 | Bazuca Films | false |
| 32 | Good Luck Chuck | - | - | - | $18,134 | 15 | $98,656 | Feb 14 | Sony Pictures Releasing | false |
| 33 | Hannibal Rising | - | - | - | $16,665 | 11 | $92,151 | Jan 31 | United International Pictures | false |
| 34 | After the Wedding | - | - | - | $14,480 | 5 | $69,637 | Mar 27 | Transeuropa | false |
| 35 | The Kite Runner | - | - | - | $10,400 | 5 | $10,400 | Mar 6 | United International Pictures | false |
| 36 | Persepolis | - | - | - | $9,587 | 1 | $12,040 | Mar 13 | Sony Pictures Releasing | false |
| 37 | The Education of Fairies | - | - | - | $6,022 | 1 | $6,022 | Mar 13 | Walt Disney Pictures | false |
| 38 | Bridge to Terabithia | - | - | - | $5,112 | 14 | $63,520 | Jan 3 | United International Pictures | false |
| 39 | Microfilia | - | - | - | $2,387 | 8 | $12,159 | Mar 13 | Los Filmes de la Arcadia | false |
| 40 | Gone Baby Gone | - | - | - | $2,062 | 4 | $30,917 | Jan 24 | Walt Disney Pictures | false |
| 41 | Michael Clayton | - | - | - | $1,327 | 15 | $189,470 | Dec 6 | Bazuca Films | false |
| 42 | Papelucho y el marciano | - | - | - | $565 | 33 | $969,819 | May 17 | Bazuca Films | false |
| 43 | Radio Corazón | - | - | - | $550 | 40 | $1,941,625 | Oct 4 | Bazuca Films | false |
| 44 | La Vie En Rose | - | - | - | $510 | 7 | $182,652 | Aug 9 | Transeuropa | false |
| 45 | Le Sauvage | - | - | - | $419 | 6 | $19,209 | Feb 7 | Four Films | false |
| 46 | Casino Royale | - | - | - | $394 | 44 | $807,989 | Dec 7 | Sony Pictures Releasing | false |
| 47 | 1408 | - | - | - | $343 | 20 | $203,975 | Dec 27 | United International Pictures | false |
| 48 | The Mudboy | - | - | - | $227 | 2 | $227 | Feb 28 | Walt Disney Pictures | false |
| 49 | In the Land of Women | - | - | - | $106 | 6 | $7,326 | Feb 21 | CDI Films | false |
| 50 | The Golden Compass | - | - | - | $97 | 50 | $849,398 | Dec 13 | Warner Bros. | false |
