| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Walk the Line | - | - | - | $584,845 | 60 | $1,866,575 | Feb 9 | 20th Century Fox International | false |
| 2 | Date Movie | - | - | - | $475,610 | 50 | $536,365 | Mar 2 | 20th Century Fox International | false |
| 3 | Underworld: Evolution | - | - | - | $408,998 | 48 | $532,972 | Mar 16 | Sony Pictures Releasing | false |
| 4 | The Pink Panther | - | - | - | $285,497 | 40 | $410,563 | Mar 16 | 20th Century Fox International | false |
| 5 | Hostel | - | - | - | $269,507 | 34 | $487,950 | Feb 23 | Sony Pictures Releasing | false |
| 6 | Brokeback Mountain | - | - | - | $250,689 | 20 | $781,901 | Feb 9 | Roadshow Films | false |
| 7 | Æon Flux | - | - | - | $157,389 | 39 | $334,070 | Feb 23 | United International Pictures | false |
| 8 | Naming Number Two | - | - | - | $151,571 | 38 | $433,904 | Feb 16 | Buena Vista International | false |
| 9 | Firewall | - | - | - | $144,849 | 36 | $144,849 | Mar 2 | Roadshow Films | false |
| 10 | Lord of War | - | - | - | $129,215 | 37 | $195,861 | Mar 23 | Hoyts Distribution | false |
| 11 | Casanova | - | - | - | $116,759 | 46 | $140,292 | Mar 2 | Buena Vista International | false |
| 12 | Syriana | - | - | - | $116,162 | 17 | $187,732 | Feb 23 | Warner Bros. | false |
| 13 | A History of Violence | - | - | - | $112,225 | 16 | $11 | Mar 16 | Roadshow Films | false |
| 14 | Big Momma's House 2 | - | - | - | $106,625 | 50 | $405,462 | Feb 16 | 20th Century Fox International | false |
| 15 | Capote | - | - | - | $93,010 | 10 | $226,931 | Feb 18 | Sony Pictures Releasing | false |
| 16 | Wolf Creek | - | - | - | $91,039 | 38 | $91,039 | Mar 9 | Roadshow Films | false |
| 17 | Derailed | - | - | - | $80,297 | 36 | $106,549 | Mar 23 | Buena Vista International | false |
| 18 | The World's Fastest Indian | - | - | - | $79,930 | 68 | $4,600,313 | Oct 13 | REP Distribution | false |
| 19 | The Producers | - | - | - | $74,151 | 35 | $152,842 | Feb 23 | Sony Pictures Releasing | false |
| 20 | The White Countess | - | - | - | $66,293 | 10 | $113,078 | Mar 16 | Sony Pictures Releasing | false |
| 21 | Mrs. Henderson Presents | - | - | - | $63,043 | 41 | $897,657 | Mar 30 | Hopscotch Films | false |
| 22 | Crash | - | - | - | $59,373 | 44 | $398,418 | Aug 25 | Icon Film Distribution Australia | false |
| 23 | Separate Lies | - | - | - | $56,994 | 10 | $84,003 | Feb 23 | 20th Century Fox International | false |
| 24 | In Search of Mozart | - | - | - | $46,856 | 8 | $75,687 | Mar 2 | - | false |
| 25 | The Weather Man | - | - | - | $33,773 | 33 | $33,773 | Mar 16 | United International Pictures | false |
| 26 | Tristan + Isolde | - | - | - | $30,997 | 35 | $45,491 | Mar 9 | 20th Century Fox International | false |
| 27 | River Queen | - | - | - | $26,726 | 40 | $617,299 | Jan 26 | 20th Century Fox International | false |
| 28 | Hustle & Flow | - | - | - | $26,207 | 15 | $26,207 | Mar 2 | United International Pictures | false |
| 29 | The Constant Gardener | - | - | - | $25,033 | 31 | $901,871 | Nov 17 | United International Pictures | false |
| 30 | Cry Wolf | - | - | - | $16,675 | 19 | $16,675 | Mar 23 | United International Pictures | false |
| 31 | Goal! The Dream Begins | - | - | - | $15,725 | 40 | $57,805 | Feb 23 | Roadshow Films | false |
| 32 | Waiting... | - | - | - | $15,333 | 27 | $15,333 | Mar 9 | Hoyts Distribution | false |
| 33 | Nanny McPhee | - | - | - | $10,226 | 50 | $619,496 | Jan 5 | United International Pictures | false |
| 34 | Proof | - | - | - | $7,627 | 7 | $23,266 | Mar 16 | Buena Vista International | false |
