| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Max Th | Opening | % of Total
| Open Th | Open | Close | Distributor
| Estimated
|
|---|
| 1 | Inside Man | - | - | - | $14,406,413 | 356 | $3,145,035 | 21.8% | 355 | Mar 24 | - | United International Pictures | false |
| 2 | The Pink Panther | - | - | - | $10,577,372 | 406 | $3,409,631 | 32.2% | 403 | Mar 17 | - | 20th Century Fox International | false |
| 3 | Hostel | - | - | - | $7,736,178 | 304 | $2,116,564 | 27.4% | 304 | Mar 24 | - | Sony Pictures Releasing | false |
| 4 | Syriana | - | - | - | $7,162,144 | 236 | $1,514,608 | 21.1% | 236 | Mar 3 | - | Warner Bros. | false |
| 5 | The Hills Have Eyes | - | - | - | $6,255,176 | 331 | $1,944,483 | 31.1% | 331 | Mar 10 | - | 20th Century Fox International | false |
| 6 | Failure to Launch | - | - | - | $5,540,067 | 353 | $1,880,936 | 34% | 352 | Mar 31 | - | United International Pictures | false |
| 7 | The Shaggy Dog | - | - | - | $5,534,468 | 430 | $1,443,894 | 26.1% | 417 | Mar 31 | - | Buena Vista International | false |
| 8 | The Ringer | - | - | - | $3,267,338 | 261 | $975,649 | 29.9% | 261 | Mar 24 | - | 20th Century Fox International | false |
| 9 | Deep Sea | - | - | - | $2,869,929 | 3 | - | - | - | Mar 3 | - | IMAX | false |
| 10 | Yours, Mine & Ours | - | - | - | $2,369,263 | 265 | $574,370 | 24.2% | 252 | Mar 31 | - | Sony Pictures Releasing | false |
| 11 | Firewall | - | - | - | $2,234,517 | 281 | $809,241 | 36.2% | 281 | Mar 31 | - | Warner Bros. | false |
| 12 | Last Holiday | - | - | - | $2,074,431 | 199 | $699,729 | 33.7% | 198 | Mar 3 | - | United International Pictures | false |
| 13 | Basic Instinct 2 | - | - | - | $2,050,960 | 290 | $845,981 | 41.2% | 290 | Mar 31 | - | Entertainment Film Distributors | false |
| 14 | The Weather Man | - | - | - | $1,947,395 | 258 | $711,544 | 36.5% | 258 | Mar 3 | - | Momentum Pictures | false |
| 15 | The Matador | - | - | - | $1,511,538 | 221 | $586,751 | 38.8% | 221 | Mar 3 | - | Buena Vista International | false |
| 16 | Tsotsi | - | - | - | $1,442,451 | 87 | $351,310 | 24.4% | 86 | Mar 17 | - | Momentum Pictures | false |
| 17 | Transamerica | - | - | - | $1,392,753 | 42 | $240,086 | 17.2% | 42 | Mar 24 | - | Pathé | false |
| 18 | The Proposition | - | - | - | $1,157,037 | 118 | $354,858 | 30.7% | 118 | Mar 10 | - | Tartan | false |
| 19 | Kidulthood | - | - | - | $849,650 | 42 | $175,239 | 20.6% | 41 | Mar 3 | - | Revolver Entertainment | false |
| 20 | The World's Fastest Indian | - | - | - | $840,237 | 78 | $199,620 | 23.8% | 78 | Mar 10 | - | Icon Film Distribution Australia | false |
| 21 | The Three Burials of Melquiades Estrada | - | - | - | $720,843 | 29 | $143,453 | 19.9% | 29 | Mar 31 | - | Optimum Releasing | false |
| 22 | Two for the Money | - | - | - | $614,467 | 158 | $284,797 | 46.3% | 158 | Mar 10 | - | United International Pictures | false |
| 23 | Malamaal Weekly | - | - | - | $549,397 | 19 | $121,951 | 22.2% | 14 | Mar 10 | - | Tip Top Entertainment (TTE) | false |
| 24 | The White Countess | - | - | - | $540,512 | 57 | $121,612 | 22.5% | 52 | Mar 31 | - | Sony Pictures Releasing | false |
| 25 | Romance & Cigarettes | - | - | - | $439,112 | 29 | $120,365 | 27.4% | 29 | Mar 24 | - | Icon Film Distribution Australia | false |
| 26 | Shooting Dogs 2006 Re-release | - | - | - | $286,065 | 20 | $61,668 | 21.6% | 20 | Mar 31 | - | Metrodome Distribution | false |
| 27 | The Child | - | - | - | $234,477 | 3 | - | - | - | Mar 10 | - | Artificial Eye | false |
| 28 | Ushpizin | - | - | - | $64,248 | - | - | - | - | Mar 17 | - | - | false |
| 29 | Stay | - | - | - | $56,727 | - | - | - | - | Mar 3 | - | - | false |
| 30 | The Ballad of Jack and Rose | - | - | - | $37,698 | 3 | - | - | - | Mar 31 | - | Entertainment Film Distributors | false |
