| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | The Pink Panther | - | - | - | $6,987,772 | 406 | $10,577,372 | Mar 17 | 20th Century Fox International | false |
| 2 | Date Movie | - | - | - | $6,252,911 | 356 | $8,762,281 | Feb 24 | 20th Century Fox International | false |
| 3 | Syriana | - | - | - | $6,014,102 | 236 | $7,162,144 | Mar 3 | Warner Bros. | false |
| 4 | Walk the Line | - | - | - | $5,858,187 | 290 | $17,780,351 | Feb 3 | 20th Century Fox International | false |
| 5 | Lucky Number Slevin | - | - | - | $5,848,960 | 326 | $7,956,571 | Feb 24 | Entertainment Film Distributors | false |
| 6 | The Hills Have Eyes | - | - | - | $5,814,363 | 331 | $6,255,176 | Mar 10 | 20th Century Fox International | false |
| 7 | V for Vendetta | - | - | - | $4,823,342 | 410 | $20,863 | Oct 30 | Warner Bros. | false |
| 8 | Inside Man | - | - | - | $4,642,766 | 356 | $14,406,413 | Mar 24 | United International Pictures | false |
| 9 | Chicken Little | - | - | - | $4,211,276 | 513 | $23,557,158 | Feb 10 | Buena Vista International | false |
| 10 | Big Momma's House 2 | - | - | - | $3,678,687 | 317 | $16,107,165 | Feb 10 | 20th Century Fox International | false |
| 11 | Hostel | - | - | - | $3,443,804 | 304 | $7,736,178 | Mar 24 | Sony Pictures Releasing | false |
| 12 | Final Destination 3 | - | - | - | $3,257,215 | 347 | $15,869,800 | Feb 10 | Entertainment Film Distributors | false |
| 13 | Last Holiday | - | - | - | $2,064,153 | 199 | $2,074,431 | Mar 3 | United International Pictures | false |
| 14 | The Weather Man | - | - | - | $1,817,248 | 258 | $1,947,395 | Mar 3 | Momentum Pictures | false |
| 15 | Capote | - | - | - | $1,745,237 | 66 | $2,870,941 | Feb 24 | Sony Pictures Releasing | false |
| 16 | Good Night, and Good Luck. | - | - | - | $1,715,116 | 139 | $4,400,071 | Feb 19 | Redbus Film Distribution | false |
| 17 | Brokeback Mountain | - | - | - | $1,703,536 | 284 | $17,957,778 | Jan 6 | Entertainment Film Distributors | false |
| 18 | The Ringer | - | - | - | $1,587,633 | 261 | $3,267,338 | Mar 24 | 20th Century Fox International | false |
| 19 | The Matador | - | - | - | $1,511,538 | 221 | $1,511,538 | Mar 3 | Buena Vista International | false |
| 20 | The Proposition | - | - | - | $987,126 | 118 | $1,157,037 | Mar 10 | Tartan | false |
| 21 | Tsotsi | - | - | - | $922,299 | 87 | $1,442,451 | Mar 17 | Momentum Pictures | false |
| 22 | Zathura: A Space Adventure | - | - | - | $772,443 | 404 | $7,650,052 | Feb 3 | Sony Pictures Releasing | false |
| 23 | The Constant Gardener | - | - | - | $738,757 | 301 | $10,751,629 | Nov 11 | United International Pictures | false |
| 24 | Two for the Money | - | - | - | $611,299 | 158 | $614,467 | Mar 10 | United International Pictures | false |
| 25 | Kidulthood | - | - | - | $607,408 | 42 | $849,650 | Mar 3 | Revolver Entertainment | false |
| 26 | The Fog | - | - | - | $494,286 | 211 | $861,502 | Feb 24 | Sony Pictures Releasing | false |
| 27 | Malamaal Weekly | - | - | - | $431,406 | 19 | $549,397 | Mar 10 | Tip Top Entertainment (TTE) | false |
| 28 | Munich | - | - | - | $428,491 | 383 | $8,959,351 | Jan 27 | United International Pictures | false |
| 29 | The World's Fastest Indian | - | - | - | $416,258 | 78 | $840,237 | Mar 10 | Icon Film Distribution Australia | false |
| 30 | Transamerica | - | - | - | $407,106 | 42 | $1,392,753 | Mar 24 | Pathé | false |
| 31 | Memoirs of a Geisha | - | - | - | $240,914 | 288 | $12,663,017 | Jan 13 | Buena Vista International | false |
| 32 | Caché | - | - | - | $182,211 | 40 | $2,667,906 | Jan 27 | Artificial Eye | false |
| 33 | Romance & Cigarettes | - | - | - | $179,053 | 29 | $439,112 | Mar 24 | Icon Film Distribution Australia | false |
| 34 | Stay | - | - | - | $56,895 | - | $56,727 | Mar 3 | - | false |
