| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Good Morning, Vietnam | - | - | - | $25,435,519 | 1,598 | $123,922,370 | Dec 25 | Walt Disney Studios Motion Pictures | false |
| 2 | Moonstruck | - | - | - | $15,452,221 | 1,178 | $80,640,528 | Dec 18 | Metro-Goldwyn-Mayer (MGM) | false |
| 3 | Frantic | - | - | - | $14,350,129 | 1,101 | $17,637,950 | Feb 26 | Warner Bros. | false |
| 4 | Three Men and a Baby | - | - | - | $14,162,885 | 1,813 | $167,780,960 | Nov 25 | Walt Disney Studios Motion Pictures | false |
| 5 | Shoot to Kill | - | - | - | $13,201,777 | 1,519 | $29,300,090 | Feb 12 | Walt Disney Studios Motion Pictures | false |
| 6 | Police Academy 5: Assignment: Miami Beach | - | - | - | $12,527,901 | 1,700 | $19,510,371 | Mar 18 | Warner Bros. | false |
| 7 | Masquerade | - | - | - | $11,520,708 | 1,031 | $15,855,828 | Mar 11 | Metro-Goldwyn-Mayer (MGM) | false |
| 8 | Bloodsport | - | - | - | $11,411,533 | 124 | $11,806,119 | Feb 26 | Cannon Film Distributors | false |
| 9 | Vice Versa | - | - | - | $11,276,379 | 1,225 | $13,664,060 | Mar 11 | Columbia Pictures | false |
| 10 | Moving | - | - | - | $10,815,378 | 1,404 | $10,815,378 | Mar 4 | Warner Bros. | false |
| 11 | Biloxi Blues | - | - | - | $10,359,670 | 1,330 | $43,184,798 | Mar 25 | Universal Pictures | false |
| 12 | School Daze | - | - | - | $9,980,083 | 224 | $14,545,844 | Feb 12 | Columbia Pictures | false |
| 13 | Switching Channels | - | - | - | $9,129,999 | 971 | $9,129,999 | Mar 4 | TriStar Pictures | false |
| 14 | D.O.A. | - | - | - | $8,576,778 | 908 | $12,706,478 | Mar 18 | Walt Disney Studios Motion Pictures | false |
| 15 | The Fox and the Hound 1988 Re-release | - | - | - | $7,484,901 | 1,567 | $23,556,988 | Mar 25 | Walt Disney Studios Motion Pictures | false |
| 16 | Action Jackson | - | - | - | $7,372,244 | 1,249 | $20,256,975 | Feb 12 | Lorimar Motion Pictures | false |
| 17 | Johnny Be Good | - | - | - | $7,314,610 | 1,194 | $17,550,399 | Mar 25 | Orion Pictures | false |
| 18 | Off Limits | - | - | - | $7,242,035 | 1,371 | $7,242,035 | Mar 11 | Twentieth Century Fox | false |
| 19 | The Last Emperor | - | - | - | $6,070,867 | 877 | $43,984,230 | Nov 20 | Columbia Pictures | false |
| 20 | A Night in the Life of Jimmy Reardon | - | - | - | $4,408,446 | 882 | $6,264,058 | Feb 26 | Twentieth Century Fox | false |
| 21 | Hairspray | - | - | - | $3,988,690 | 227 | $6,671,108 | Feb 26 | New Line Cinema | false |
| 22 | She's Having a Baby | - | - | - | $3,956,592 | 1,133 | $16,031,707 | Feb 5 | Paramount Pictures | false |
| 23 | A New Life | - | - | - | $3,475,009 | 796 | $7,721,852 | Mar 25 | Paramount Pictures | false |
| 24 | The Serpent and the Rainbow | - | - | - | $3,405,130 | 1,431 | $19,595,031 | Feb 5 | Universal Pictures | false |
| 25 | The Unbearable Lightness of Being | - | - | - | $3,368,962 | 140 | $10,006,806 | Feb 5 | Orion Pictures | false |
| 26 | Broadcast News | - | - | - | $2,299,683 | 848 | $51,249,404 | Dec 18 | Twentieth Century Fox | false |
| 27 | Stand and Deliver | - | - | - | $2,293,501 | 472 | $13,994,920 | Mar 11 | Warner Bros. | false |
| 28 | Satisfaction | - | - | - | $2,131,489 | 1,018 | $8,253,123 | Feb 12 | Twentieth Century Fox | false |
| 29 | Ironweed | - | - | - | $1,784,215 | 600 | $7,393,346 | Dec 18 | TriStar Pictures | false |
| 30 | Little Nikita | - | - | - | $1,614,993 | 376 | $1,733,070 | Mar 18 | Columbia Pictures | false |
| 31 | Sammy and Rosie Get Laid | - | - | - | $882,707 | 15 | $1,196,336 | Oct 30 | Cinecom Pictures | false |
| 32 | And God Created Woman | - | - | - | $717,376 | 385 | $717,376 | Mar 4 | Vestron Pictures | false |
| 33 | Fatal Attraction | - | - | - | $523,086 | 1,401 | $156,645,693 | Sep 18 | Paramount Pictures | false |
| 34 | Dominick and Eugene | - | - | - | $402,065 | 76 | $3,076,031 | Mar 18 | Orion Pictures | false |
| 35 | Hope and Glory | - | - | - | $329,865 | 328 | $10,021,120 | Oct 16 | Columbia Pictures | false |
| 36 | The Milagro Beanfield War | - | - | - | $232,907 | 437 | $13,825,794 | Mar 18 | Universal Pictures | false |
| 37 | Taffin | - | - | - | $68,556 | 204 | $159,969 | Feb 26 | Metro-Goldwyn-Mayer (MGM) | false |
| 38 | Beatrice | - | - | - | $17,838 | 8 | $211,821 | Mar 18 | The Samuel Goldwyn Company | false |
| 39 | Aria | - | - | - | $10,574 | 34 | $1,028,679 | Mar 18 | Miramax | false |
| 40 | When the Wind Blows | - | - | - | $5,274 | 1 | $5,274 | Mar 11 | - | false |
