| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Alice Through the Looking Glass | - | - | - | $3,964,951 | 726 | $7,374,314 | May 25 | Walt Disney Pictures | false |
| 2 | Warcraft | - | - | - | $3,369,465 | 510 | $3,976,000 | Jun 1 | Universal Pictures International (UPI) | false |
| 3 | Now You See Me 2 | - | - | - | $2,599,168 | 430 | $3,227,428 | Jun 8 | Medusa Distribuzione | false |
| 4 | The Angry Birds Movie | - | - | - | $2,475,044 | 573 | $3,645,280 | Jun 15 | Sony Pictures Releasing | false |
| 5 | Like Crazy | - | - | - | $2,325,600 | 468 | $6,788,270 | May 17 | 01 Distribution | false |
| 6 | The Nice Guys | - | - | - | $1,959,990 | 351 | $2,105,444 | Jun 1 | Lucky Red | false |
| 7 | The Conjuring 2 | - | - | - | $1,488,923 | 380 | $2,800,000 | Jun 23 | Warner Bros. | false |
| 8 | Julieta | - | - | - | $1,283,035 | 315 | $2,476,404 | May 26 | Warner Bros. | false |
| 9 | Pele: Birth of a Legend | - | - | - | $1,261,984 | 267 | $2,191,284 | May 26 | M2 Pictures | false |
| 10 | X-Men: Apocalypse | - | - | - | $1,052,919 | 699 | $5,810,167 | May 18 | 20th Century Fox International | false |
| 11 | The Man Who Knew Infinity | - | - | - | $910,100 | 223 | $1,200,726 | Jun 9 | Eagle Pictures | false |
| 12 | Miami Beach | - | - | - | $813,302 | 354 | $877,095 | Jun 1 | 01 Distribution | false |
| 13 | Misconduct | - | - | - | $626,993 | 250 | $699,372 | Jun 15 | Lucky Red | false |
| 14 | Made in Italy: Ciao Brother | - | - | - | $617,475 | 102 | $774,653 | Jun 9 | Microcinema | false |
| 15 | Friend Request | - | - | - | $579,378 | 174 | $689,224 | Jun 8 | Adler Entertainment | false |
| 16 | Before I Wake | - | - | - | $433,519 | 217 | $972,423 | May 25 | Koch Media | false |
| 17 | Captain America: Civil War | - | - | - | $373,685 | 969 | $12,963,449 | May 4 | Walt Disney Pictures | false |
| 18 | Everybody Wants Some!! | - | - | - | $261,650 | 175 | $506,414 | Jun 16 | Notorious Pictures | false |
| 19 | Mother's Day | - | - | - | $259,911 | 211 | $424,052 | Jun 23 | 01 Distribution | false |
| 20 | The Wild Life | - | - | - | $206,272 | 340 | $1,324,987 | May 5 | Notorious Pictures | false |
| 21 | Kalinka | - | - | - | $203,060 | 71 | $240,294 | Jun 9 | Good Films | false |
| 22 | The Jungle Book | - | - | - | $179,435 | 766 | $11,956,478 | Apr 14 | Walt Disney Pictures | false |
| 23 | Kiki, Love to Love | - | - | - | $161,191 | 145 | $336,351 | Jun 23 | Videa | false |
| 24 | Fiore | - | - | - | $151,531 | 54 | $204,185 | May 25 | BIM Distribuzione | false |
| 25 | Monster Hunt | - | - | - | $135,281 | 247 | $1,138,689 | May 12 | Microcinema | false |
| 26 | Money Monster | - | - | - | $129,973 | 382 | $2,432,639 | May 12 | Sony Pictures Releasing | false |
| 27 | Tra la terra e il cielo | - | - | - | $120,298 | 39 | $126,199 | Jun 1 | - | false |
| 28 | The Neon Demon | - | - | - | $112,432 | 196 | $129,660 | Jun 8 | Koch Media | false |
| 29 | The Boss | - | - | - | $82,984 | 114 | $108,341 | Jun 16 | Universal Pictures International (UPI) | false |
| 30 | Ma ma | - | - | - | $73,562 | 122 | $78,801 | Jun 16 | I Wonder Pictures | false |
| 31 | Eddie the Eagle | - | - | - | $57,092 | 75 | $57,092 | Jun 2 | 20th Century Fox International | false |
| 32 | Colonia | - | - | - | $52,679 | 127 | $185,421 | May 26 | Good Films | false |
| 33 | Louder Than Bombs | - | - | - | $36,722 | 49 | $36,722 | Jun 23 | Teodora Film | false |
| 34 | My Father Jack | - | - | - | $35,505 | 73 | $232,616 | May 19 | Zenit Distribution | false |
| 35 | Escape from Planet Earth 2016 Re-release | - | - | - | $31,856 | 264 | $341,546 | Apr 28 | 01 Distribution | false |
| 36 | Atlit 2016 Re-release | - | - | - | $30,716 | 21 | $31,053 | Jun 16 | Parthenos | false |
| 37 | Marguerite & Julien | - | - | - | $21,844 | 27 | $23,802 | Jun 1 | Officine UBU | false |
| 38 | Piégé | - | - | - | $19,585 | 60 | $19,585 | Jun 23 | Istituto Luce | false |
| 39 | Gueros 2016 Re-release | - | - | - | $3,228 | 6 | $15,618 | Jun 23 | Bunker Hill | false |
| 40 | Zootopia | - | - | - | $254 | 615 | $12,643,572 | Feb 18 | Walt Disney Pictures | false |
