| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | The Hangover | - | - | - | $179,606 | 7 | $293,731 | Jun 12 | Garsu Pasaulio Irasai | false |
| 2 | Terminator Salvation | - | - | - | $169,053 | 10 | $174,455 | Jun 5 | Sony Pictures Releasing | false |
| 3 | The Proposal | - | - | - | $75,499 | 7 | $162,068 | Jun 19 | Universal Pictures International (UPI) | false |
| 4 | Angels & Demons | - | - | - | $67,482 | 10 | $293,688 | May 15 | Sony Pictures Releasing | false |
| 5 | Drag Me to Hell | - | - | - | $60,559 | 5 | $68,993 | Jun 12 | ACME | false |
| 6 | Fighting | - | - | - | $57,886 | 7 | $79,705 | May 29 | Universal Pictures International (UPI) | false |
| 7 | Night at the Museum: Battle of the Smithsonian | - | - | - | $53,765 | 8 | $104,857 | May 22 | Universal Pictures International (UPI) | false |
| 8 | Ghosts of Girlfriends Past | - | - | - | $49,604 | 7 | $67,524 | May 29 | Garsu Pasaulio Irasai | false |
| 9 | New in Town | - | - | - | $48,515 | 5 | $48,515 | Jun 5 | ACME | false |
| 10 | Transformers: Revenge of the Fallen | - | - | - | $47,215 | 10 | $220,242 | Jun 26 | Universal Pictures International (UPI) | false |
| 11 | Monsters vs. Aliens | - | - | - | $21,325 | 10 | $232,224 | Apr 3 | Universal Pictures International (UPI) | false |
| 12 | Coraline | - | - | - | $11,212 | 2 | $51,771 | May 8 | Universal Pictures International (UPI) | false |
| 13 | 17 Again | - | - | - | $8,450 | 7 | $131,594 | May 8 | Garsu Pasaulio Irasai | false |
| 14 | The Uninvited | - | - | - | $5,593 | 3 | $22,666 | May 22 | Universal Pictures International (UPI) | false |
| 15 | Dark Planet: Rebellion | - | - | - | $5,591 | 5 | $11,096 | May 29 | ACME | false |
| 16 | My Bloody Valentine | - | - | - | $4,679 | 8 | $124,231 | Apr 24 | ACME | false |
| 17 | Jonas Brothers: The 3D Concert Experience | - | - | - | $4,566 | 2 | $4,820 | Jun 12 | Universal Pictures International (UPI) | false |
| 18 | State of Play | - | - | - | $3,569 | 1 | $7,725 | Jun 19 | Universal Pictures International (UPI) | false |
| 19 | Home | - | - | - | $2,973 | 1 | $2,973 | Jun 5 | - | false |
| 20 | Ultimate Heist | - | - | - | $2,853 | 2 | $6,943 | Jun 26 | ACME | false |
| 21 | The Tale of Despereaux | - | - | - | $2,041 | 10 | $282,007 | Dec 26 | Universal Pictures International (UPI) | false |
| 22 | Milk | - | - | - | $1,326 | 1 | $1,326 | - | - | false |
| 23 | Delta | - | - | - | $1,264 | 1 | $1,443 | May 29 | - | false |
| 24 | Race to Witch Mountain | - | - | - | $1,137 | 6 | $36,174 | Apr 17 | Universal Pictures International (UPI) | false |
| 25 | Observe and Report | - | - | - | $1,126 | 5 | $22,897 | May 15 | Garsu Pasaulio Irasai | false |
| 26 | Star Trek | - | - | - | $1,060 | 3 | $25,748 | May 8 | Universal Pictures International (UPI) | false |
| 27 | Gran Torino | - | - | - | $454 | 3 | $41,204 | Mar 27 | Garsu Pasaulio Irasai | false |
| 28 | The Boy in the Striped Pajamas | - | - | - | $440 | 3 | $79,868 | Jan 2 | Universal Pictures International (UPI) | false |
| 29 | Hotel for Dogs | - | - | - | $402 | 8 | $51,159 | Mar 20 | Universal Pictures International (UPI) | false |
| 30 | I Love You, Man | - | - | - | $357 | 6 | $37,227 | Apr 24 | Universal Pictures International (UPI) | false |
| 31 | X-Men Origins: Wolverine | - | - | - | $181 | 8 | $61,702 | May 1 | Universal Pictures International (UPI) | false |
| 32 | Beverly Hills Chihuahua | - | - | - | $148 | 7 | $136,136 | Feb 6 | Universal Pictures International (UPI) | false |
| 33 | Doubt | - | - | - | $64 | 2 | $12,740 | Jan 30 | Universal Pictures International (UPI) | false |
| 34 | Marley & Me | - | - | - | $15 | 8 | $139,599 | Mar 13 | Universal Pictures International (UPI) | false |
| 35 | The Crimson Wing: Mystery of the Flamingos | - | - | - | $11 | 4 | $23,572 | Mar 13 | Universal Pictures International (UPI) | false |
