| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Sex and the City | - | - | - | $412,108 | 17 | $487,698 | Jun 6 | Alexandra Films | false |
| 2 | Indiana Jones and the Kingdom of the Crystal Skull | - | - | - | $286,903 | 21 | $744,379 | May 23 | Prooptiki | false |
| 3 | The Incredible Hulk | - | - | - | $82,946 | 10 | $97,910 | Jun 13 | Prooptiki | false |
| 4 | The Happening | - | - | - | $81,879 | 9 | $90,646 | Jun 13 | Alexandra Films | false |
| 5 | Wanted | - | - | - | $77,217 | 15 | $354,689 | Jun 27 | Prooptiki | false |
| 6 | What Happens in Vegas | - | - | - | $51,459 | 7 | $177,357 | May 16 | Alexandra Films | false |
| 7 | 88 Minutes | - | - | - | $49,741 | 5 | $78,519 | May 30 | Alexandra Films | false |
| 8 | A Prueba De Hombres | - | - | - | $39,422 | 5 | $70,097 | Jun 20 | Alexandra Films | false |
| 9 | Horton Hears a Who! | - | - | - | $27,767 | 13 | $151,756 | Apr 25 | Alexandra Films | false |
| 10 | My Blueberry Nights | - | - | - | $23,087 | 4 | $32,660 | Jun 13 | Sunny Films | false |
| 11 | Love in the Time of Cholera | - | - | - | $16,862 | 4 | $35,645 | May 30 | Prooptiki | false |
| 12 | Mongol: The Rise of Genghis Khan | - | - | - | $16,452 | 5 | $25,939 | Jun 20 | Sunny Films | false |
| 13 | Iron Man | - | - | - | $10,599 | 11 | $157,124 | May 2 | Prooptiki | false |
| 14 | 21 | - | - | - | $9,578 | 9 | $126,661 | May 9 | Alexandra Films | false |
| 15 | Shutter | - | - | - | $9,283 | 5 | $22,137 | Jun 27 | Alexandra Films | false |
| 16 | Fool's Gold | - | - | - | $5,945 | 8 | $137,649 | May 2 | Alexandra Films | false |
| 17 | Speed Racer | - | - | - | $5,613 | 6 | $18,759 | May 16 | Alexandra Films | false |
| 18 | Surviving with Wolves | - | - | - | $3,946 | 4 | $6,722 | May 30 | Sunny Films | false |
| 19 | Street Kings | - | - | - | $2,602 | 8 | $128,753 | Apr 18 | Alexandra Films | false |
| 20 | Forgetting Sarah Marshall | - | - | - | $2,482 | 4 | $44,480 | Apr 25 | Prooptiki | false |
| 21 | The Spiderwick Chronicles | - | - | - | $2,340 | 8 | $74,419 | Apr 4 | Prooptiki | false |
| 22 | The Eye | - | - | - | $2,235 | 6 | $40,920 | Apr 25 | Alexandra Films | false |
| 23 | The Bucket List | - | - | - | $2,091 | 6 | $103,453 | Apr 11 | Alexandra Films | false |
| 24 | 99 Francs | - | - | - | $1,816 | 3 | $13,013 | May 9 | Big Bang Media | false |
| 25 | The Game Plan | - | - | - | $1,542 | 4 | $85,175 | Mar 21 | Sunny Films | false |
| 26 | Mad Money | - | - | - | $1,119 | 5 | $36,397 | Apr 18 | Sunny Films | false |
| 27 | The Mist | - | - | - | $1,041 | 4 | $26,838 | Apr 4 | Sunny Films | false |
| 28 | In the Valley of Elah | - | - | - | $673 | 4 | $7,761 | Apr 18 | Prooptiki | false |
| 29 | Definitely, Maybe | - | - | - | $639 | 4 | $19,319 | Apr 11 | Prooptiki | false |
| 30 | There Will Be Blood | - | - | - | $299 | 4 | $24,432 | Mar 28 | Sunny Films | false |
| 31 | Elizabeth: The Golden Age | - | - | - | $161 | 8 | $69,045 | Nov 30 | Prooptiki | false |
| 32 | In the Name of the King: A Dungeon Siege Tale | - | - | - | $137 | 7 | $105,574 | Mar 21 | Tandem Films | false |
| 33 | The Mosquito Problem and Other Stories | - | - | - | $109 | 2 | $2,864 | Mar 14 | Sunny Films | false |
| 34 | Georgi and the Butterflies | - | - | - | $99 | 1 | $6,433 | Apr 15 | Sunny Films | false |
| 35 | Michael Clayton | - | - | - | $96 | 6 | $95,750 | Feb 29 | Sunny Films | false |
| 36 | National Treasure: Book of Secrets | - | - | - | $80 | 12 | $413,445 | Dec 21 | Sunny Films | false |
| 37 | You, the Living | - | - | - | $61 | 1 | $1,346 | Apr 18 | Big Bang Media | false |
| 38 | 3:10 to Yuma | - | - | - | $39 | 5 | $28,488 | Feb 29 | Tandem Films | false |
| 39 | The Singer (Quand j'étais chanteur) | - | - | - | $8 | 5 | $10,289 | Nov 9 | Alexandra Films | false |
| 40 | No Country for Old Men | - | - | - | $8 | 4 | $80,700 | Feb 22 | Prooptiki | false |
| 41 | The Nanny Diaries | - | - | - | $5 | 4 | $23,874 | Nov 23 | Sunny Films | false |
