| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Pirates of the Caribbean: At World's End | - | - | - | $2,129,267 | 127 | $3,336,141 | May 25 | - | false |
| 2 | Shrek the Third | - | - | - | $1,272,697 | 129 | $3,522,403 | Jun 22 | - | false |
| 3 | Spider-Man 3 | - | - | - | $537,622 | 109 | $3,017,668 | May 4 | - | false |
| 4 | 28 Weeks Later | - | - | - | $429,141 | 32 | $505,147 | Jun 8 | - | false |
| 5 | Zodiac | - | - | - | $355,150 | 26 | $379,444 | Jun 1 | - | false |
| 6 | 13 segundos | - | - | - | $328,568 | 30 | $1,404,294 | Apr 20 | - | false |
| 7 | Mr. Bean's Holiday | - | - | - | $285,881 | 76 | $576,332 | May 18 | - | false |
| 8 | Turistas | - | - | - | $228,710 | 22 | $440,605 | Jun 15 | - | false |
| 9 | Perfume: The Story of a Murderer | - | - | - | $154,311 | 20 | $393,168 | May 11 | - | false |
| 10 | A Virgin Grandmother | - | - | - | $148,747 | 16 | $1,256,116 | Mar 2 | - | false |
| 11 | Epic Movie | - | - | - | $138,148 | 31 | $571,252 | May 11 | - | false |
| 12 | Cry Wolf | - | - | - | $89,179 | 24 | $252,430 | May 18 | - | false |
| 13 | Wild Hogs | - | - | - | $88,059 | 32 | $1,020,589 | Apr 20 | - | false |
| 14 | Hard Candy | - | - | - | $86,580 | 10 | $99,968 | Jun 8 | - | false |
| 15 | Russian Dolls | - | - | - | $52,949 | 6 | $73,060 | Jun 8 | - | false |
| 16 | Cake | - | - | - | $42,284 | 10 | $95,225 | May 11 | - | false |
| 17 | The Wind that Shakes the Barley | - | - | - | $23,070 | 3 | $27,954 | Jun 15 | - | false |
| 18 | The Valet | - | - | - | $22,653 | 7 | $34,173 | Jun 15 | - | false |
| 19 | Curse of the Golden Flower | - | - | - | $20,849 | 12 | $119,677 | Apr 27 | - | false |
| 20 | Keeping Mum | - | - | - | $12,143 | 12 | $105,447 | May 4 | - | false |
| 21 | The Reaping | - | - | - | $8,110 | 52 | $1,078,410 | Apr 20 | - | false |
| 22 | Primeval | - | - | - | $3,527 | 16 | $171,824 | Apr 27 | - | false |
| 23 | Five Times Two | - | - | - | $1,329 | 2 | $44,056 | Apr 27 | - | false |
| 24 | Meet the Robinsons | - | - | - | $1,125 | 59 | $1,717,847 | Mar 30 | - | false |
