| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Poseidon | - | - | - | $1,169,142 | 101 | $1,576,114 | Jun 1 | Warner Bros. | false |
| 2 | X-Men: The Last Stand | - | - | - | $842,815 | 108 | $1,964,264 | May 25 | 20th Century Fox International | false |
| 3 | The Break-Up | - | - | - | $584,724 | 60 | $1,300,503 | Jun 15 | United International Pictures | false |
| 4 | Cars | - | - | - | $477,389 | 165 | $3,314,539 | Jun 22 | Buena Vista International | false |
| 5 | Mission: Impossible III | - | - | - | $361,576 | 128 | $2,773,801 | May 3 | United International Pictures | false |
| 6 | The Omen | - | - | - | $321,387 | 45 | $479,599 | Jun 8 | 20th Century Fox International | false |
| 7 | 16 Blocks | - | - | - | $197,498 | 40 | $307,348 | Jun 15 | Benelux Film Distributors | false |
| 8 | Silent Hill | - | - | - | $160,522 | 35 | $367,647 | May 25 | RCV Film Distribution | false |
| 9 | Marie Antoinette | - | - | - | $156,055 | 22 | $336,212 | Jun 8 | A-Film Distribution | false |
| 10 | Ice Age 2: The Meltdown | - | - | - | $148,254 | 195 | $7,869,645 | Mar 30 | 20th Century Fox International | false |
| 11 | The Shaggy Dog | - | - | - | $120,405 | 40 | $368,004 | May 25 | Buena Vista International | false |
| 12 | American Dreamz | - | - | - | $118,119 | 24 | $148,297 | Jun 1 | United International Pictures | false |
| 13 | Take the Lead | - | - | - | $116,337 | 30 | $116,864 | Jun 1 | Paradiso Entertainment | false |
| 14 | The Wild | - | - | - | $95,444 | 79 | $791,571 | Apr 20 | Buena Vista International | false |
| 15 | Asterix and the Vikings | - | - | - | $53,697 | 60 | $521,476 | Apr 20 | Independent Films | false |
| 16 | Memoirs of a Geisha | - | - | - | $37,673 | 35 | $1,038,326 | Apr 6 | Sony Pictures Releasing | false |
| 17 | Heading South | - | - | - | $35,665 | 5 | $65,415 | Jun 15 | A-Film Distribution | false |
| 18 | The Road to Guantanamo | - | - | - | $22,294 | 7 | $24,549 | Jun 1 | A-Film Distribution | false |
| 19 | The Little Polar Bear 2: The Mysterious Island | - | - | - | $20,430 | 81 | $401,394 | Apr 27 | Warner Bros. | false |
| 20 | The White Massai | - | - | - | $19,142 | 13 | $369,627 | Mar 16 | Benelux Film Distributors | false |
| 21 | Inside Man | - | - | - | $17,488 | 65 | $2,216,906 | Mar 23 | United International Pictures | false |
| 22 | Comedy of Power | - | - | - | $17,005 | 5 | $39,212 | Jun 22 | Paradiso Entertainment | false |
| 23 | Scary Movie 4 | - | - | - | $9,887 | 80 | $2,250,804 | Apr 13 | Buena Vista International | false |
| 24 | The Libertine | - | - | - | $8,972 | 10 | $58,746 | May 18 | Paradiso Entertainment | false |
| 25 | Ask the Dust | - | - | - | $8,078 | 15 | $15,683 | Jun 22 | Benelux Film Distributors | false |
| 26 | Man About Town | - | - | - | $5,578 | 8 | $18,624 | Jun 8 | Moonlight Films | false |
| 27 | Brokeback Mountain | - | - | - | $4,126 | 40 | $1,988,502 | Feb 16 | A-Film Distribution | false |
| 28 | The Promise | - | - | - | $3,150 | 8 | $3,605 | Jun 15 | Sony Pictures Releasing | false |
