| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Harry Potter and the Deathly Hallows: Part 2 | - | - | - | $21,741,610 | 1,008 | $29,775,040 | Jul 13 | Warner Bros. | false |
| 2 | Transformers: Dark of the Moon | - | - | - | $9,826,473 | 702 | $12,398,269 | Jul 1 | United International Pictures | false |
| 3 | Cars 2 | - | - | - | $6,403,210 | 834 | $14,421,348 | Jun 22 | Walt Disney Pictures | false |
| 4 | Captain America: The First Avenger | - | - | - | $5,987,588 | 556 | $8,601,080 | Jul 22 | United International Pictures | false |
| 5 | Season of the Witch | - | - | - | $1,067,868 | 349 | $4,383,131 | Jun 17 | Medusa Distribuzione | false |
| 6 | Second Chance | - | - | - | $1,049,916 | 179 | $1,449,548 | Jul 13 | Moviemax | false |
| 7 | The Adjustment Bureau | - | - | - | $919,502 | 295 | $2,640,766 | Jun 17 | Universal Pictures International (UPI) | false |
| 8 | Welcome to the South | - | - | - | $715,728 | 568 | $43,015,634 | Oct 1 | Medusa Distribuzione | false |
| 9 | The Women on the 6th Floor | - | - | - | $543,819 | 61 | $1,673,306 | Jun 10 | - | false |
| 10 | Snow Flower and the Secret Fan | - | - | - | $489,404 | 111 | $550,573 | Jul 8 | Eagle Pictures | false |
| 11 | You Got Served: Beat the World | - | - | - | $467,857 | 164 | $467,947 | Jul 1 | - | false |
| 12 | Qualunquemente | - | - | - | $385,207 | 589 | $22,862,029 | Jan 21 | 01 Distribution | false |
| 13 | The Immature | - | - | - | $366,156 | 519 | $21,858,834 | Jan 21 | Medusa Distribuzione | false |
| 14 | Get Him to the Greek | - | - | - | $329,273 | 107 | $329,273 | Jul 8 | United International Pictures | false |
| 15 | Hall Pass | - | - | - | $319,102 | 247 | $1,802,615 | Jun 17 | Warner Bros. | false |
| 16 | The Conspirator | - | - | - | $296,803 | 72 | $574,917 | Jun 22 | 01 Distribution | false |
| 17 | Bitch Slap | - | - | - | $240,151 | 147 | $240,151 | Jul 22 | Eagle Pictures | false |
| 18 | Women Vs Men | - | - | - | $237,844 | 625 | $16,719,346 | Feb 4 | Medusa Distribuzione | false |
| 19 | Escort in Love | - | - | - | $216,660 | 485 | $11,471,250 | Mar 16 | 01 Distribution | false |
| 20 | War Games | - | - | - | $207,071 | 68 | $322,562 | Jul 22 | Bolero Film | false |
| 21 | Diary of a Wimpy Kid | - | - | - | $173,560 | 100 | $533,730 | Jul 28 | 20th Century Fox International | false |
| 22 | The Tree of Life | - | - | - | $131,961 | 181 | $3,863,901 | May 18 | 01 Distribution | false |
| 23 | Hypnosis | - | - | - | $128,900 | 49 | $211,681 | Jun 24 | - | false |
| 24 | X-Men: First Class | - | - | - | $123,128 | 522 | $3,982,424 | Jun 8 | 20th Century Fox International | false |
| 25 | The Kid with a Bike | - | - | - | $119,237 | 63 | $1,106,665 | May 18 | Lucky Red | false |
| 26 | 13 Assassins | - | - | - | $111,335 | 105 | $263,079 | Jun 24 | BIM Distribuzione | false |
| 27 | London Boulevard | - | - | - | $69,891 | 120 | $825,402 | Jun 10 | 01 Distribution | false |
| 28 | Michel Petrucciani | - | - | - | $68,739 | 20 | $115,327 | Jun 22 | - | false |
| 29 | The Hangover Part II | - | - | - | $66,559 | 576 | $13,505,147 | May 27 | Warner Bros. | false |
| 30 | Black Venus | - | - | - | $50,315 | 29 | $151,340 | Jun 17 | Lucky Red | false |
| 31 | The King's Speech | - | - | - | $46,436 | 228 | $12,493,249 | Jan 28 | Eagle Pictures | false |
| 32 | Big Mommas: Like Father, Like Son | - | - | - | $40,569 | 17 | $40,569 | Jul 8 | 20th Century Fox International | false |
| 33 | Monte Carlo | - | - | - | $36,894 | 10 | $36,894 | Jul 22 | 20th Century Fox International | false |
| 34 | African Cats | - | - | - | $36,486 | 39 | $36,486 | Jul 22 | Walt Disney Pictures | false |
| 35 | Balkan Bazaar | - | - | - | $35,626 | 7 | $36,335 | Jul 13 | Mediaplex | false |
| 36 | You Again | - | - | - | $34,225 | 16 | $34,225 | Jul 8 | Walt Disney Pictures | false |
| 37 | Hereafter | - | - | - | $33,221 | 371 | $11,240,698 | Jan 5 | Warner Bros. | false |
| 38 | Scream 4 | - | - | - | $28,498 | 220 | $1,870,406 | Apr 15 | Moviemax | false |
| 39 | The End Is My Beginning | - | - | - | $27,060 | 100 | $1,178,390 | Apr 1 | Fandango | false |
| 40 | Corpo Celeste 2011 Re-release | - | - | - | $26,712 | 23 | $306,413 | May 27 | - | false |
| 41 | We Have a Pope | - | - | - | $26,115 | 453 | $7,894,680 | Apr 15 | 01 Distribution | false |
| 42 | Fist of the North Star: The Legends of the True Savior: Legend of Raoh-Chapter of Death in Love 2008 Re-release | - | - | - | $23,711 | 56 | $26,568 | Jul 4 | Mikado Film | false |
| 43 | Another Year | - | - | - | $22,922 | 69 | $1,188,074 | Feb 4 | BIM Distribuzione | false |
| 44 | La vita facile | - | - | - | $21,246 | 324 | $3,801,152 | Mar 4 | Medusa Distribuzione | false |
| 45 | The First Assignment | - | - | - | $18,993 | 21 | $260,294 | May 6 | Teodora Film | false |
| 46 | In a Better World | - | - | - | $18,975 | 40 | $807,897 | Dec 10 | Teodora Film | false |
| 47 | Zack and Miri Make a Porno | - | - | - | $18,497 | 151 | $630,524 | Jun 1 | - | false |
| 48 | Giallo 2011 Re-release | - | - | - | $17,458 | 34 | $17,458 | Jul 1 | - | false |
| 49 | Barney's Version | - | - | - | $16,171 | 235 | $3,764,747 | Jan 14 | Medusa Distribuzione | false |
| 50 | Vanishing on 7th Street | - | - | - | $16,168 | 13 | $46,957 | Jul 28 | One Movie | false |
| 51 | Hands Up | - | - | - | $14,354 | 32 | $191,105 | Jun 1 | Teodora Film | false |
| 52 | Mother and Child | - | - | - | $10,015 | 10 | $10,015 | Jul 21 | DNC Entertainment | false |
| 53 | Angel & Tony | - | - | - | $9,479 | 27 | $261,097 | Apr 29 | Sacher Distribuzione | false |
| 54 | Julia's Eyes | - | - | - | $7,864 | 155 | $622,776 | May 11 | Moviemax | false |
| 55 | What a Beautiful Day | - | - | - | $7,837 | 798 | $59,370,498 | Jan 5 | Medusa Distribuzione | false |
| 56 | Sorelle mai | - | - | - | $7,743 | 41 | $429,931 | Mar 16 | Teodora Film | false |
| 57 | The Tree | - | - | - | $7,033 | 5 | $18,124 | Jul 6 | - | false |
| 58 | Burke and Hare | - | - | - | $5,240 | 53 | $325,040 | Feb 25 | Archibald | false |
| 59 | The Solitude of Prime Numbers | - | - | - | $4,634 | 371 | $4,928,162 | Sep 10 | Medusa Distribuzione | false |
| 60 | The Jewel | - | - | - | $4,611 | 175 | $1,368,586 | Mar 4 | BIM Distribuzione | false |
| 61 | Lost Kisses | - | - | - | $3,298 | 41 | $151,454 | Apr 29 | - | false |
| 62 | Rio | - | - | - | $3,041 | 626 | $9,204,958 | Apr 15 | 20th Century Fox International | false |
| 63 | Never Let Me Go | - | - | - | $2,211 | 99 | $590,123 | Mar 25 | 20th Century Fox International | false |
| 64 | Grave Encounters | - | - | - | $2,198 | 173 | $2,408,334 | Jun 1 | Eagle Pictures | false |
| 65 | The Salt of Life | - | - | - | $2,172 | 182 | $1,135,249 | Feb 11 | 01 Distribution | false |
| 66 | L'erede - The Heir | - | - | - | $2,169 | 5 | $19,691 | Jul 6 | - | false |
| 67 | A Quiet Life | - | - | - | $1,956 | 164 | $2,021,470 | Nov 5 | 01 Distribution | false |
| 68 | Inception | - | - | - | $1,935 | 585 | $15,459,083 | Sep 24 | Warner Bros. | false |
| 69 | The Social Network | - | - | - | $1,741 | 311 | $3,758,965 | Nov 12 | Sony Pictures Releasing | false |
| 70 | Il pezzo mancante | - | - | - | $1,646 | 3 | $33,181 | Jun 17 | - | false |
| 71 | Greenberg | - | - | - | $1,614 | 97 | $189,582 | Apr 8 | BIM Distribuzione | false |
| 72 | Due Date | - | - | - | $1,549 | 272 | $5,406,458 | Jan 28 | Warner Bros. | false |
| 73 | Route Irish | - | - | - | $1,503 | 70 | $555,955 | Apr 20 | BIM Distribuzione | false |
| 74 | Cirkus Columbia | - | - | - | $1,462 | 18 | $46,445 | May 27 | Archibald | false |
| 75 | Gorbaciof | - | - | - | $1,265 | 133 | $879,825 | Oct 15 | Lucky Red | false |
| 76 | Source Code | - | - | - | $1,204 | 309 | $2,718,562 | Apr 29 | 01 Distribution | false |
| 77 | True Grit | - | - | - | $1,194 | 318 | $4,183,698 | Feb 18 | Universal Pictures International (UPI) | false |
| 78 | You Will Meet a Tall Dark Stranger | - | - | - | $1,089 | 393 | $6,487,957 | Dec 3 | Medusa Distribuzione | false |
