| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | The Twilight Saga: Eclipse | - | - | - | $218,469,293 | 4,468 | $300,531,751 | Jun 30 | Summit Entertainment | false |
| 2 | Despicable Me | - | - | - | $185,594,440 | 3,602 | $251,639,815 | Jul 9 | Universal Pictures | false |
| 3 | Inception | - | - | - | $184,734,433 | 3,792 | $292,576,195 | Jul 16 | Warner Bros. | false |
| 4 | Toy Story 3 | - | - | - | $136,750,522 | 4,028 | $415,004,880 | Jun 18 | Walt Disney Studios Motion Pictures | false |
| 5 | The Last Airbender | - | - | - | $126,701,787 | 3,203 | $131,772,187 | Jul 1 | Paramount Pictures | false |
| 6 | Grown Ups | - | - | - | $94,967,816 | 3,534 | $162,001,186 | Jun 25 | Sony Pictures Releasing | false |
| 7 | Salt | - | - | - | $65,124,331 | 3,612 | $118,311,368 | Jul 23 | Sony Pictures Releasing | false |
| 8 | The Sorcerer's Apprentice | - | - | - | $50,646,644 | 3,504 | $63,150,991 | Jul 14 | Walt Disney Studios Motion Pictures | false |
| 9 | Predators | - | - | - | $49,161,892 | 2,669 | $52,000,688 | Jul 9 | Twentieth Century Fox | false |
| 10 | Knight and Day 2010 Re-release | - | - | - | $40,532,255 | 3,104 | $76,423,035 | Jun 23 | Twentieth Century Fox | false |
| 11 | The Karate Kid | - | - | - | $30,892,405 | 3,740 | $176,591,618 | Jun 11 | Sony Pictures Releasing | false |
| 12 | Dinner for Schmucks | - | - | - | $16,738,281 | 3,046 | $73,026,337 | Jul 30 | DreamWorks | false |
| 13 | Ramona and Beezus | - | - | - | $15,304,701 | 2,719 | $26,167,002 | Jul 23 | Twentieth Century Fox | false |
| 14 | The A-Team | - | - | - | $10,626,974 | 3,544 | $77,222,099 | Jun 11 | Twentieth Century Fox | false |
| 15 | Charlie St. Cloud | - | - | - | $9,459,560 | 2,725 | $31,162,545 | Jul 30 | Universal Pictures | false |
| 16 | Cats & Dogs: The Revenge of Kitty Galore | - | - | - | $8,842,399 | 3,705 | $43,585,753 | Jul 30 | Warner Bros. | false |
| 17 | The Kids Are All Right | - | - | - | $8,553,164 | 994 | $20,811,365 | Jul 9 | Focus Features | false |
| 18 | Cyrus | - | - | - | $6,158,344 | 454 | $7,468,936 | Jun 18 | - | false |
| 19 | Get Him to the Greek | - | - | - | $4,722,270 | 2,702 | $60,974,475 | Jun 4 | Universal Pictures | false |
| 20 | Shrek Forever After | - | - | - | $4,392,943 | 4,386 | $238,736,787 | May 21 | DreamWorks | false |
| 21 | Iron Man 2 | - | - | - | $3,836,047 | 4,390 | $312,433,331 | May 7 | Paramount Pictures | false |
| 22 | The Girl Who Played with Fire | - | - | - | $3,474,734 | 185 | $7,638,241 | Jul 9 | Music Box Films | false |
| 23 | I Am Love | - | - | - | $2,979,473 | 166 | $5,005,465 | Jun 18 | Magnolia Pictures | false |
| 24 | Letters to Juliet | - | - | - | $2,752,946 | 2,975 | $53,032,453 | May 14 | Summit Entertainment | false |
| 25 | Hubble | - | - | - | $2,705,910 | 151 | $52,522,904 | Mar 19 | Warner Bros. | false |
| 26 | Winter's Bone | - | - | - | $2,702,076 | 141 | $6,531,503 | Jun 11 | Roadside Attractions | false |
| 27 | Marmaduke | - | - | - | $2,465,402 | 3,213 | $33,644,788 | Jun 4 | Twentieth Century Fox | false |
| 28 | Prince of Persia: The Sands of Time | - | - | - | $2,420,248 | 3,646 | $90,759,676 | May 28 | Walt Disney Studios Motion Pictures | false |
| 29 | Killers | - | - | - | $1,992,057 | 2,859 | $47,059,963 | Jun 4 | Lionsgate Films | false |
| 30 | Solitary Man | - | - | - | $1,897,556 | 177 | $4,360,548 | May 21 | Anchor Bay Films | false |
| 31 | How to Train Your Dragon | - | - | - | $1,866,417 | 4,060 | $217,581,231 | Mar 26 | DreamWorks | false |
| 32 | Robin Hood | - | - | - | $1,659,850 | 3,505 | $105,269,730 | May 14 | Universal Pictures | false |
| 33 | Joan Rivers: A Piece of Work | - | - | - | $1,562,037 | 115 | $2,930,687 | Jun 11 | IFC Films | false |
| 34 | Sex and the City 2 | - | - | - | $1,542,252 | 3,445 | $95,347,692 | May 27 | Warner Bros. | false |
| 35 | Date Night | - | - | - | $1,105,484 | 3,380 | $98,711,404 | Apr 9 | Twentieth Century Fox | false |
| 36 | The Girl with the Dragon Tattoo | - | - | - | $938,723 | 202 | $10,095,170 | Mar 19 | Music Box Films | false |
| 37 | The Secret in Their Eyes | - | - | - | $811,702 | 166 | $6,391,436 | Apr 16 | Sony Pictures Classics | false |
| 38 | I Hate Luv Storys | - | - | - | $810,415 | 85 | $847,993 | Jun 30 | UTV Motion Pictures | false |
| 39 | Coco Chanel & Igor Stravinsky | - | - | - | $808,355 | 74 | $1,621,226 | Jun 11 | Sony Pictures Classics | false |
| 40 | Jonah Hex | - | - | - | $706,064 | 2,825 | $10,547,117 | Jun 18 | Warner Bros. | false |
| 41 | Please Give | - | - | - | $670,449 | 272 | $4,033,574 | Apr 30 | Sony Pictures Classics | false |
| 42 | Under the Sea 3D | - | - | - | $662,992 | 108 | $36,262,926 | Feb 13 | Warner Bros. | false |
| 43 | Splice 2010 Re-release | - | - | - | $642,493 | 2,450 | $17,010,170 | Jun 4 | Warner Bros. | false |
| 44 | Restrepo | - | - | - | $560,150 | 52 | $1,330,894 | Jun 25 | National Geographic Entertainment | false |
| 45 | Standing Ovation | - | - | - | $531,806 | 625 | $531,806 | Jul 16 | Rocky Mountain Pictures | false |
| 46 | Clash of the Titans | - | - | - | $441,208 | 3,802 | $163,214,888 | Apr 2 | Warner Bros. | false |
| 47 | City Island | - | - | - | $441,097 | 269 | $6,671,036 | Mar 19 | Anchor Bay Films | false |
| 48 | Khatta Meetha | - | - | - | $440,060 | 83 | $541,904 | Jul 23 | Eros Worldwide | false |
| 49 | Magnificent Desolation: Walking on the Moon | - | - | - | $427,753 | 82 | $34,137,524 | Sep 23 | IMAX | false |
| 50 | Exit Through the Gift Shop | - | - | - | $374,114 | 46 | $3,291,250 | Apr 16 | - | false |
| 51 | Micmacs | - | - | - | $333,382 | 52 | $1,262,079 | May 28 | Sony Pictures Classics | false |
| 52 | Grease 2010 Sing-a-long | - | - | - | $289,126 | 33 | $365,802 | Jul 8 | Paramount Pictures | false |
| 53 | Furry Vengeance | - | - | - | $280,070 | 3,002 | $17,630,465 | Apr 30 | Summit Entertainment | false |
| 54 | Just Wright | - | - | - | $265,864 | 1,831 | $21,540,363 | May 14 | - | false |
| 55 | Mother and Child | - | - | - | $238,568 | 119 | $1,110,509 | May 7 | Sony Pictures Classics | false |
| 56 | Wild Grass | - | - | - | $227,718 | 23 | $403,952 | Jun 25 | Sony Pictures Classics | false |
| 57 | Diary of a Wimpy Kid | - | - | - | $223,127 | 3,083 | $64,003,625 | Mar 19 | Twentieth Century Fox | false |
| 58 | Ondine | - | - | - | $213,178 | 39 | $550,472 | Jun 4 | Magnolia Pictures | false |
| 59 | The Back-up Plan | - | - | - | $198,375 | 3,280 | $37,490,007 | Apr 23 | CBS Films | false |
| 60 | Harry Brown | - | - | - | $191,359 | 67 | $1,818,681 | Apr 30 | The Samuel Goldwyn Company | false |
| 61 | Avatar | - | - | - | $182,570 | 3,461 | $749,766,139 | Dec 18 | Twentieth Century Fox | false |
| 62 | Death at a Funeral | - | - | - | $165,169 | 2,459 | $42,739,347 | Apr 16 | Screen Gems | false |
| 63 | South of the Border | - | - | - | $154,561 | 12 | $198,600 | Jun 25 | Cinema Libre Studio | false |
| 64 | The Killer Inside Me | - | - | - | $144,028 | 17 | $217,277 | Jun 18 | IFC Films | false |
| 65 | Deep Sea | - | - | - | $142,774 | 47 | $46,412,757 | Mar 3 | Warner Bros. | false |
| 66 | Oceans | - | - | - | $137,829 | 1,232 | $19,422,319 | Apr 22 | Walt Disney Studios Motion Pictures | false |
| 67 | A Nightmare on Elm Street | - | - | - | $135,630 | 3,332 | $63,075,011 | Apr 30 | Warner Bros. | false |
| 68 | The Last Song | - | - | - | $131,210 | 2,794 | $62,950,384 | Mar 31 | Walt Disney Studios Motion Pictures | false |
| 69 | Agora | - | - | - | $127,347 | 17 | $619,423 | May 28 | Newmarket Films | false |
| 70 | Love Ranch | - | - | - | $125,522 | 11 | $137,885 | Jun 30 | - | false |
| 71 | Countdown to Zero | - | - | - | $94,068 | 28 | $272,040 | Jul 23 | Magnolia Pictures | false |
| 72 | Babies | - | - | - | $92,774 | 543 | $7,320,323 | May 7 | Focus Features | false |
| 73 | The Bounty Hunter | - | - | - | $88,397 | 3,118 | $67,061,228 | Mar 19 | Sony Pictures Releasing | false |
| 74 | Breathless 2010 Re-release | - | - | - | $84,538 | 12 | $363,031 | May 28 | Rialto Pictures | false |
| 75 | Mademoiselle Chambon | - | - | - | $80,535 | 16 | $531,685 | May 28 | Lorber Films | false |
| 76 | Winnebago Man | - | - | - | $64,529 | 12 | $181,039 | Jul 9 | Kino International | false |
| 77 | The City of Your Final Destination | - | - | - | $63,447 | 26 | $493,296 | Apr 16 | Screen Media Films | false |
| 78 | La Mission | - | - | - | $57,733 | 47 | $1,062,941 | Apr 9 | Screen Media Films | false |
| 79 | Life During Wartime | - | - | - | $57,294 | 20 | $281,447 | Jul 23 | IFC Films | false |
| 80 | Metropolis 2010 Re-release | - | - | - | $53,539 | 9 | $529,603 | May 7 | Kino International | false |
| 81 | God of Vampires | - | - | - | $53,345 | 10 | $53,345 | Jul 2 | Nocturnal Features | false |
| 82 | Jean-Michel Basquiat: The Radiant Child | - | - | - | $52,538 | 7 | $256,242 | Jul 21 | Arthouse Films | false |
| 83 | Stonewall Uprising | - | - | - | $51,304 | 10 | $128,203 | Jun 16 | First Run | false |
| 84 | Mid-August Lunch | - | - | - | $51,091 | 23 | $675,299 | Mar 17 | Zeitgeist Films | false |
| 85 | 71: Into the Fire | - | - | - | $50,431 | 20 | $176,638 | Jul 30 | - | false |
| 86 | Let it Rain | - | - | - | $49,103 | 6 | $111,844 | Jun 18 | IFC Films | false |
| 87 | Kisses 2010 Re-release | - | - | - | $42,576 | 11 | $81,680 | Jul 16 | Oscilloscope | false |
| 88 | Get Low | - | - | - | $37,488 | 570 | $9,176,933 | Jul 30 | Sony Pictures Classics | false |
| 89 | Holy Rollers | - | - | - | $35,481 | 20 | $303,064 | May 21 | First Independent Pictures | false |
| 90 | The Secret of Kells | - | - | - | $33,681 | 37 | $676,775 | Mar 5 | GKIDS | false |
| 91 | Dogtooth | - | - | - | $31,667 | 5 | $110,248 | Jun 25 | Kino International | false |
| 92 | Sea Monsters: A Prehistoric Adventure | - | - | - | $31,073 | 252 | $23,746,066 | Oct 5 | National Geographic Entertainment | false |
| 93 | Princess Kaiulani | - | - | - | $29,324 | 47 | $883,887 | May 14 | Roadside Attractions | false |
| 94 | Best Worst Movie | - | - | - | $25,631 | 2 | $109,895 | Apr 23 | Abramorama | false |
| 95 | Valhalla Rising | - | - | - | $25,032 | 2 | $30,638 | Jul 16 | IFC Films | false |
| 96 | Rosencrantz and Guildenstern Are Undead | - | - | - | $24,716 | 4 | $71,007 | Jun 4 | Indican Pictures | false |
| 97 | Orlando 2010 Re-release | - | - | - | $23,468 | 5 | $58,198 | Jul 23 | Sony Pictures Classics | false |
| 98 | [Rec]² | - | - | - | $22,800 | 7 | $27,766 | Jul 9 | Magnolia Pictures | false |
| 99 | Raavan | - | - | - | $22,766 | 120 | $708,726 | Jun 18 | Reliance Big Pictures | false |
| 100 | Raajneeti | - | - | - | $20,793 | 124 | $1,514,558 | Jun 4 | UTV Motion Pictures | false |
| 101 | The Square 2010 Re-release | - | - | - | $20,791 | 24 | $406,116 | Apr 9 | Apparition | false |
| 102 | The Nature of Existence | - | - | - | $19,583 | 4 | $54,645 | Jun 18 | Walking Shadows | false |
| 103 | Alamar | - | - | - | $19,449 | 3 | $61,613 | Jul 14 | Film Movement | false |
| 104 | Alice in Wonderland | - | - | - | $18,798 | 3,739 | $334,191,110 | Mar 5 | Walt Disney Studios Motion Pictures | false |
| 105 | Racing Dreams | - | - | - | $18,422 | 33 | $65,082 | May 21 | Hannover House | false |
| 106 | The Lottery | - | - | - | $17,982 | 3 | $54,543 | Jun 11 | Variance Films | false |
| 107 | Around a Small Mountain | - | - | - | $17,508 | 3 | $33,216 | Jul 9 | The Cinema Guild | false |
| 108 | House | - | - | - | $17,479 | 7 | $209,765 | Jan 15 | Janus Films | false |
| 109 | 8: The Mormon Proposition | - | - | - | $17,001 | 16 | $100,280 | Jun 18 | - | false |
| 110 | Kings of the Evening | - | - | - | $16,769 | 5 | $99,270 | Jun 11 | Indican Pictures | false |
| 111 | Great Directors | - | - | - | $16,600 | 4 | $17,921 | Jul 2 | Paladin | false |
| 112 | Only the Brave | - | - | - | $15,913 | 5 | $150,000 | May 28 | Indican Pictures | false |
| 113 | Everyone Else | - | - | - | $15,869 | 5 | $102,042 | Apr 9 | The Cinema Guild | false |
| 114 | 2012: Time for Change | - | - | - | $14,341 | 2 | $68,339 | Apr 9 | Mangusta Productions | false |
| 115 | The Concert | - | - | - | $13,371 | 21 | $657,986 | Jul 30 | The Weinstein Company | false |
| 116 | Cropsey | - | - | - | $12,878 | 4 | $52,476 | Jun 4 | Cinema Purgatorio | false |
| 117 | Feed the Fish | - | - | - | $11,868 | 4 | $101,170 | Apr 23 | Strand Releasing | false |
| 118 | The Sun Behind the Clouds: Tibet's Struggle for Freedom | - | - | - | $11,622 | 4 | $67,095 | Mar 31 | Balcony Releasing | false |
| 119 | John Rabe | - | - | - | $11,303 | 6 | $67,519 | May 21 | Strand Releasing | false |
| 120 | Henri-Georges Clouzot's Inferno | - | - | - | $11,262 | 3 | $25,489 | Jul 16 | Flicker Alley | false |
| 121 | U2 3D | - | - | - | $11,057 | 686 | $10,363,341 | Jan 23 | National Geographic Entertainment | false |
| 122 | OSS 117: Lost in Rio | - | - | - | $10,594 | 7 | $89,375 | May 7 | Music Box Films | false |
| 123 | Sweetgrass | - | - | - | $10,351 | 9 | $207,473 | Jan 6 | The Cinema Guild | false |
| 124 | The Joneses | - | - | - | $9,227 | 217 | $1,475,746 | Apr 16 | Roadside Attractions | false |
| 125 | The Oath | - | - | - | $9,092 | 4 | $42,273 | May 7 | Zeitgeist Films | false |
| 126 | Beetle Queen Conquers Tokyo | - | - | - | $8,954 | 3 | $32,308 | May 12 | Argot Pictures | false |
| 127 | The Extra Man | - | - | - | $8,900 | 33 | $453,377 | Jul 30 | Magnolia Pictures | false |
| 128 | All About Evil | - | - | - | $7,995 | 1 | $7,995 | Jul 9 | - | false |
| 129 | Survival of the Dead | - | - | - | $7,218 | 20 | $101,740 | May 28 | Magnolia Pictures | false |
| 130 | Ajami | - | - | - | $7,063 | 23 | $622,403 | Feb 3 | Kino International | false |
| 131 | Udaan | - | - | - | $6,997 | 2 | $7,461 | Jul 16 | UTV Motion Pictures | false |
| 132 | Kick-Ass | - | - | - | $6,881 | 3,065 | $48,071,303 | Apr 16 | Lionsgate Films | false |
| 133 | The Wildest Dream | - | - | - | $6,866 | 21 | $898,137 | Aug 6 | National Geographic Entertainment | false |
| 134 | Ran 2010 Re-release | - | - | - | $6,682 | 4 | $124,673 | Feb 5 | Rialto Pictures | false |
| 135 | Only When I Dance | - | - | - | $5,382 | 1 | $8,738 | Jul 2 | Film Movement | false |
| 136 | The Cremaster Cycle 2010 Re-release | - | - | - | $5,265 | 2 | $151,239 | Apr 9 | International Film Circuit | false |
| 137 | In My Sleep | - | - | - | $5,228 | 2 | $30,158 | Apr 23 | - | false |
| 138 | The Dry Land | - | - | - | $5,221 | 5 | $11,777 | Jul 30 | Freestyle Releasing | false |
| 139 | Space Station 3D | - | - | - | $5,210 | 64 | $93,383,953 | Apr 19 | IMAX | false |
| 140 | When You're Strange | - | - | - | $4,854 | 8 | $246,078 | Apr 9 | Abramorama | false |
| 141 | Spoken Word | - | - | - | $4,662 | 4 | $32,961 | Jul 23 | Variance Films | false |
| 142 | Casino Jack and the United States of Money | - | - | - | $3,900 | 21 | $176,865 | May 7 | Magnolia Pictures | false |
| 143 | A Town Called Panic | - | - | - | $3,885 | 10 | $165,509 | Dec 16 | Zeitgeist Films | false |
| 144 | Behind the Burly Q | - | - | - | $3,485 | 2 | $23,889 | Apr 23 | First Run | false |
| 145 | Mugabe and the White African | - | - | - | $3,251 | 1 | $7,924 | Jul 23 | First Run | false |
| 146 | Chloe | - | - | - | $3,135 | 350 | $3,075,255 | Mar 26 | Sony Pictures Classics | false |
| 147 | Hugh Hefner: Playboy, Activist and Rebel | - | - | - | $2,856 | 4 | $10,000 | Jul 30 | Phase 4 Films | false |
| 148 | Small Change | - | - | - | $2,689 | 2 | $38,296 | Nov 24 | The Film Desk | false |
| 149 | The Girlfriends | - | - | - | $2,623 | 1 | $68,167 | Jun 18 | The Film Desk | false |
| 150 | Breath Made Visible: Anna Halprin | - | - | - | $2,279 | 3 | $52,387 | Apr 2 | Argot Pictures | false |
| 151 | Fresh | - | - | - | $2,276 | 3 | $25,115 | Apr 9 | - | false |
| 152 | Monsieur Verdoux | - | - | - | $2,223 | 2 | $64,636 | Mar 14 | The Film Desk | false |
| 153 | Percy Jackson & the Olympians: The Lightning Thief | - | - | - | $2,209 | 3,396 | $88,768,303 | Feb 12 | Twentieth Century Fox | false |
| 154 | Off and Running | - | - | - | $1,524 | 1 | $18,262 | Jan 29 | First Run | false |
| 155 | Le combat dans l'île | - | - | - | $1,451 | 1 | $50,039 | Jun 12 | The Film Desk | false |
| 156 | Enemies of the People | - | - | - | $1,244 | 6 | $73,171 | Jul 30 | International Film Circuit | false |
| 157 | The Living Wake | - | - | - | $1,107 | 1 | $12,232 | May 14 | Mangusta Productions | false |
| 158 | Smash His Camera | - | - | - | $1,040 | 1 | $3,644 | Jul 30 | Magnolia Pictures | false |
| 159 | A Prophet | - | - | - | $897 | 83 | $2,087,720 | Feb 26 | Sony Pictures Classics | false |
| 160 | The Sicilian Girl 2010 Re-release | - | - | - | $894 | 6 | $71,239 | Aug 4 | Music Box Films | false |
| 161 | In/Significant Others | - | - | - | $868 | 1 | $3,763 | May 14 | North Poplar Pictures | false |
| 162 | The Most Dangerous Man in America: Daniel Ellsberg and the Pentagon Papers | - | - | - | $761 | 12 | $453,993 | Jan 29 | First Run | false |
| 163 | Videocracy | - | - | - | $655 | 1 | $23,720 | Feb 12 | Kino International | false |
| 164 | Here and There | - | - | - | $545 | 5 | $27,156 | May 14 | Cinema Purgatorio | false |
| 165 | Father of My Children | - | - | - | $531 | 7 | $144,022 | May 21 | IFC Films | false |
| 166 | Looking for Eric | - | - | - | $419 | 11 | $55,804 | May 14 | IFC Films | false |
| 167 | The Good the Bad the Weird | - | - | - | $408 | 15 | $128,486 | Apr 23 | IFC Films | false |
| 168 | Spring Fever | - | - | - | $381 | 2 | $10,824 | Jun 4 | Strand Releasing | false |
| 169 | The Human Centipede (First Sequence) | - | - | - | $329 | 19 | $181,467 | Apr 30 | IFC Films | false |
| 170 | Double Take | - | - | - | $211 | 1 | $20,218 | Jun 2 | Kino International | false |
| 171 | Two in the Wave | - | - | - | $159 | 1 | $28,808 | May 19 | Lorber Films | false |
| 172 | American Grindhouse | - | - | - | $158 | 2 | $5,529 | Jun 18 | Lorber Films | false |
| 173 | Dancing Across Borders | - | - | - | $158 | 5 | $66,166 | Mar 26 | First Run | false |
| 174 | Touching Home | - | - | - | $126 | 7 | $116,353 | Apr 30 | CFI Releasing | false |
| 175 | Whiz Kids | - | - | - | $95 | 2 | $5,386 | Jun 4 | Shadow Distribution | false |
| 176 | Letters to God | - | - | - | $65 | 897 | $2,848,578 | Apr 9 | Vivendi Entertainment | false |
| 177 | Dream Boy | - | - | - | $55 | 1 | $6,534 | Mar 26 | Regent Releasing | false |
