| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Shrek Forever After | - | - | - | $35,329,266 | 671 | $40,037,374 | Jul 9 | Paramount Pictures International | false |
| 2 | The Twilight Saga: Eclipse | - | - | - | $25,371,597 | 818 | $30,499,010 | Jun 30 | Paris Filmes | false |
| 3 | Toy Story 3 | - | - | - | $13,613,409 | 485 | $23,613,926 | Jun 18 | Walt Disney Pictures | false |
| 4 | Knight and Day 2010 Re-release | - | - | - | $3,518,954 | 316 | $8,663,633 | Jul 16 | 20th Century Fox International | false |
| 5 | Salt | - | - | - | $2,359,692 | 250 | $7,383,735 | Jul 30 | Sony Pictures Releasing | false |
| 6 | The Well Beloved One | - | - | - | $2,298,732 | 156 | $4,922,642 | Jul 23 | Walt Disney Pictures | false |
| 7 | Predators | - | - | - | $1,631,718 | 170 | $2,017,215 | Jul 23 | 20th Century Fox International | false |
| 8 | Prince of Persia: The Sands of Time | - | - | - | $1,446,906 | 363 | $10,124,446 | Jun 4 | Walt Disney Pictures | false |
| 9 | The Back-up Plan | - | - | - | $892,603 | 163 | $3,377,721 | Jun 11 | Sony Pictures Releasing | false |
| 10 | Alice in Wonderland | - | - | - | $631,330 | 567 | $28,360,362 | Apr 23 | Walt Disney Pictures | false |
| 11 | Clash of the Titans | - | - | - | $620,367 | 554 | $16,238,888 | May 21 | Warner Bros. | false |
| 12 | Little Nicholas | - | - | - | $467,240 | 30 | $758,299 | Jul 2 | - | false |
| 13 | Letters to Juliet | - | - | - | $447,193 | 119 | $1,861,051 | Jun 11 | Paris Filmes | false |
| 14 | Whatever Works | - | - | - | $247,101 | 30 | $1,591,880 | Apr 30 | - | false |
| 15 | The Young Victoria | - | - | - | $244,352 | 37 | $511,100 | Jun 18 | Europa Filmes | false |
| 16 | The A-Team | - | - | - | $239,374 | 246 | $2,139,275 | Jun 11 | 20th Century Fox International | false |
| 17 | I Love You Phillip Morris | - | - | - | $221,978 | 52 | $1,084,987 | Jun 4 | - | false |
| 18 | Bright Star | - | - | - | $213,880 | 30 | $394,652 | Jun 25 | PlayArte Pictures | false |
| 19 | Death Proof 2010 Re-release | - | - | - | $146,140 | 47 | $452,647 | Jul 18 | PlayArte Pictures | false |
| 20 | The Secret in Their Eyes | - | - | - | $133,846 | 24 | $1,805,523 | Feb 26 | Europa Filmes | false |
| 21 | Desert Flower 2009 Re-release | - | - | - | $115,820 | 36 | $201,442 | Jun 25 | - | false |
| 22 | The Ghost Writer | - | - | - | $112,559 | 30 | $728,417 | May 28 | Paris Filmes | false |
| 23 | The Two Deaths of Quincas Wateryell | - | - | - | $92,294 | 107 | $1,212,639 | May 21 | Walt Disney Pictures | false |
| 24 | A Prophet | - | - | - | $76,804 | 6 | $170,212 | Jun 18 | Sony Pictures Releasing | false |
| 25 | The Greatest | - | - | - | $47,296 | 56 | $207,337 | Jun 18 | PlayArte Pictures | false |
| 26 | Kick-Ass | - | - | - | $44,763 | 45 | $259,701 | Jun 18 | Universal Pictures International (UPI) | false |
| 27 | Ponyo | - | - | - | $37,389 | 43 | $145,841 | Jul 30 | PlayArte Pictures | false |
| 28 | Dear John | - | - | - | $34,441 | 33 | $258,261 | May 7 | Sony Pictures Releasing | false |
| 29 | Marmaduke | - | - | - | $27,201 | 103 | $916,569 | Jun 4 | 20th Century Fox International | false |
| 30 | Cold Souls | - | - | - | $24,447 | 13 | $81,750 | Jul 9 | Europa Filmes | false |
| 31 | Sex and the City 2 | - | - | - | $22,377 | 216 | $3,185,351 | May 28 | Warner Bros. | false |
| 32 | Daddy Cool 2010 Re-release | - | - | - | $15,479 | 4 | $72,863 | Jul 2 | Pandora Filmes | false |
| 33 | The Imaginarium of Doctor Parnassus | - | - | - | $9,849 | 6 | $166,138 | May 7 | Sony Pictures Releasing | false |
| 34 | Robin Hood | - | - | - | $9,276 | 413 | $7,953,519 | May 14 | Universal Pictures International (UPI) | false |
| 35 | Ao: The Last Hunter | - | - | - | $6,922 | 5 | $14,167 | Jul 30 | - | false |
| 36 | The Last Song | - | - | - | $6,673 | 24 | $114,401 | Jun 11 | Walt Disney Pictures | false |
| 37 | Chico Xavier | - | - | - | $4,481 | 340 | $17,229,064 | Apr 2 | Sony Pictures Releasing | false |
| 38 | Frozen | - | - | - | $2,618 | 52 | $251,715 | May 28 | PlayArte Pictures | false |
| 39 | Iron Man 2 | - | - | - | $1,879 | 626 | $15,835,025 | Apr 30 | Paramount Pictures International | false |
| 40 | Furry Vengeance | - | - | - | $1,793 | 63 | $407,413 | May 21 | Paris Filmes | false |
| 41 | The Men Who Stare at Goats | - | - | - | $1,692 | 10 | $139,183 | Mar 26 | Sony Pictures Releasing | false |
| 42 | The Bounty Hunter | - | - | - | $1,656 | 137 | $3,284,719 | Apr 16 | Sony Pictures Releasing | false |
| 43 | Old Dogs | - | - | - | $1,214 | 49 | $632,898 | Apr 2 | Walt Disney Pictures | false |
