| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Ice Age: Dawn of the Dinosaurs | - | - | - | $634,118 | 14 | $1,001,818 | Jun 29 | 20th Century Fox International | false |
| 2 | Harry Potter and the Half-Blood Prince | - | - | - | $168,816 | 14 | $294,755 | Jul 15 | Warner Bros. | false |
| 3 | Knowing | - | - | - | $52,590 | 6 | $89,102 | Jun 26 | - | false |
| 4 | Up | - | - | - | $38,874 | 10 | $232,910 | Jun 5 | Walt Disney Pictures | false |
| 5 | The Reader | - | - | - | $38,690 | 5 | $93,723 | Jun 24 | - | false |
| 6 | The Proposal | - | - | - | $33,139 | 6 | $156,223 | Jul 24 | Walt Disney Pictures | false |
| 7 | Transformers: Revenge of the Fallen | - | - | - | $29,373 | 6 | $52,535 | Jun 26 | Paramount Pictures International | false |
| 8 | 17 Again | - | - | - | $24,501 | 4 | $39,465 | Jun 26 | - | false |
| 9 | Hannah Montana: The Movie | - | - | - | $23,670 | 6 | $57,523 | Jun 18 | Walt Disney Pictures | false |
| 10 | Night at the Museum: Battle of the Smithsonian | - | - | - | $17,739 | 11 | $160,290 | May 22 | 20th Century Fox International | false |
| 11 | State of Play | - | - | - | $16,066 | 6 | $31,136 | Jun 26 | Universal Pictures International (UPI) | false |
| 12 | The Merry Widow | - | - | - | $14,814 | 3 | $23,874 | Jun 26 | - | false |
| 13 | Música en espera | - | - | - | $14,188 | 5 | $57,627 | Jun 19 | - | false |
| 14 | Esperando la carroza 2: Se acabó la fiesta | - | - | - | $11,987 | 5 | $12,732 | Jul 9 | - | false |
| 15 | The Edge of Heaven | - | - | - | $10,612 | 2 | $27,264 | Jul 17 | - | false |
| 16 | New in Town | - | - | - | $9,666 | 4 | $20,105 | Jul 24 | - | false |
| 17 | Lorna's Silence | - | - | - | $9,011 | 2 | $13,163 | Jul 10 | - | false |
| 18 | Angels & Demons | - | - | - | $8,921 | 14 | $314,045 | May 15 | Sony Pictures Releasing | false |
| 19 | El ratón Pérez 2 | - | - | - | $5,475 | 7 | $9,874 | Jun 26 | Walt Disney Pictures | false |
| 20 | Giant | - | - | - | $3,617 | 4 | $51,325 | May 22 | - | false |
| 21 | Terminator Salvation | - | - | - | $3,392 | 10 | $87,991 | Jun 3 | Sony Pictures Releasing | false |
| 22 | A Christmas Tale | - | - | - | $1,639 | 1 | $6,145 | Jun 12 | - | false |
| 23 | He's Just Not That Into You | - | - | - | $1,047 | 7 | $75,006 | May 29 | - | false |
| 24 | La mañana siguiente | - | - | - | $946 | 3 | $5,334 | Jun 5 | - | false |
| 25 | Fados | - | - | - | $867 | 1 | $17,699 | May 8 | - | false |
| 26 | Earth | - | - | - | $293 | 1 | $15,029 | Apr 24 | Walt Disney Pictures | false |
| 27 | Grace Is Gone | - | - | - | $254 | 1 | $5,486 | Jun 12 | - | false |
