| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Tron: Legacy | - | - | - | $1,526,396 | 103 | $1,538,932 | Dec 31 | Ster-Kinekor Pictures | false |
| 2 | The Tourist | - | - | - | $1,482,840 | 76 | $2,285,093 | Jan 7 | Ster-Kinekor Pictures | false |
| 3 | Little Fockers | - | - | - | $1,043,383 | 72 | $1,977,706 | Dec 24 | United International Pictures | false |
| 4 | Gulliver's Travels | - | - | - | $808,605 | 64 | $1,001,891 | Jan 7 | NuMetro Distribution | false |
| 5 | Tangled | - | - | - | $616,079 | 88 | $3,090,371 | Jan 28 | Ster-Kinekor Pictures | false |
| 6 | Due Date | - | - | - | $427,988 | 61 | $1,342,183 | Dec 15 | NuMetro Distribution | false |
| 7 | The Town | - | - | - | $372,676 | 35 | $414,417 | Dec 31 | NuMetro Distribution | false |
| 8 | Spud | - | - | - | $310,342 | 85 | $2,316,147 | Dec 3 | NuMetro Distribution | false |
| 9 | Burlesque | - | - | - | $297,297 | 55 | $577,110 | Jan 21 | Ster-Kinekor Pictures | false |
| 10 | The Next Three Days | - | - | - | $296,052 | 50 | $648,787 | Jan 21 | NuMetro Distribution | false |
| 11 | Easy A | - | - | - | $263,137 | 40 | $357,211 | Jan 14 | Ster-Kinekor Pictures | false |
| 12 | The Chronicles of Narnia: The Voyage of the Dawn Treader | - | - | - | $238,760 | 113 | $1,931,605 | Dec 10 | NuMetro Distribution | false |
| 13 | Yogi Bear | - | - | - | $170,025 | 52 | $339,389 | Dec 24 | NuMetro Distribution | false |
| 14 | The Concert | - | - | - | $134,071 | 10 | $228,835 | Jan 7 | United International Pictures | false |
| 15 | Secretariat | - | - | - | $126,204 | 30 | $151,024 | Jan 14 | Ster-Kinekor Pictures | false |
| 16 | Megamind | - | - | - | $122,512 | 79 | $1,895,039 | Dec 15 | United International Pictures | false |
| 17 | Hereafter | - | - | - | $116,507 | 30 | $116,507 | Jan 14 | NuMetro Distribution | false |
| 18 | Love & Other Drugs | - | - | - | $115,396 | 36 | $615,954 | Jan 28 | NuMetro Distribution | false |
| 19 | You Will Meet a Tall Dark Stranger | - | - | - | $85,277 | 10 | $90,333 | Dec 31 | United International Pictures | false |
| 20 | Made in Dagenham | - | - | - | $61,240 | 34 | $117,007 | Jan 21 | United International Pictures | false |
| 21 | Faster | - | - | - | $47,887 | 41 | $499,347 | Dec 3 | Ster-Kinekor Pictures | false |
| 22 | Paranormal Activity 2 | - | - | - | $36,979 | 15 | $246,354 | Dec 10 | United International Pictures | false |
| 23 | Harry Potter and the Deathly Hallows: Part 1 | - | - | - | $29,185 | 112 | $2,268,033 | Nov 26 | NuMetro Distribution | false |
| 24 | Liefling | - | - | - | $24,611 | 97 | $1,842,887 | Nov 19 | Indigenous Film Distribution | false |
| 25 | Splice 2010 Re-release | - | - | - | $21,795 | 21 | $71,812 | Jan 28 | United International Pictures | false |
| 26 | Red | - | - | - | $19,200 | 45 | $815,188 | Nov 19 | NuMetro Distribution | false |
| 27 | Unstoppable | - | - | - | $16,988 | 61 | $963,953 | Nov 12 | NuMetro Distribution | false |
| 28 | Skyline | - | - | - | $14,856 | 12 | $14,856 | Jan 14 | NuMetro Distribution | false |
| 29 | The Kids Are All Right | - | - | - | $12,482 | 3 | $58,624 | Nov 12 | United International Pictures | false |
| 30 | The Social Network | - | - | - | $10,151 | 40 | $415,980 | Nov 5 | Ster-Kinekor Pictures | false |
| 31 | Eternity | - | - | - | $9,929 | 28 | $50,365 | Dec 24 | Indigenous Film Distribution | false |
| 32 | You Again | - | - | - | $6,740 | 30 | $394,708 | Nov 5 | Ster-Kinekor Pictures | false |
| 33 | Eyes Wide Open | - | - | - | $2,878 | 2 | $30,933 | Nov 12 | United International Pictures | false |
| 34 | Wolf 2010 Re-release | - | - | - | $2,531 | 4 | $11,996 | Dec 24 | Ster-Kinekor Pictures | false |
| 35 | Stoute Boudjies | - | - | - | $2,362 | 40 | $195,054 | Dec 10 | Ster-Kinekor Pictures | false |
| 36 | Coco Chanel & Igor Stravinsky | - | - | - | $1,991 | 6 | $43,142 | Nov 26 | United International Pictures | false |
| 37 | Scott Pilgrim vs. the World | - | - | - | $140 | 15 | $86,677 | Dec 3 | United International Pictures | false |
