| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Tangled | - | - | - | $6,187,505 | 103 | $8,228,969 | Jan 6 | Walt Disney Pictures | false |
| 2 | The Chronicles of Narnia: The Voyage of the Dawn Treader | - | - | - | $4,028,784 | 102 | $4,486,616 | Dec 28 | 20th Century Fox International | false |
| 3 | Little Fockers | - | - | - | $3,267,455 | 96 | $3,982,943 | Jan 6 | Universal Pictures International (UPI) | false |
| 4 | Gulliver's Travels | - | - | - | $1,351,077 | 87 | $2,273,857 | Jan 20 | 20th Century Fox International | false |
| 5 | Hereafter | - | - | - | $989,777 | 48 | $1,273,818 | Jan 6 | Warner Bros. | false |
| 6 | The Tourist | - | - | - | $787,589 | 61 | $1,629,330 | Jan 20 | Sony Pictures Releasing | false |
| 7 | Tron: Legacy | - | - | - | $648,986 | 86 | $1,948,774 | Dec 16 | Walt Disney Pictures | false |
| 8 | Yogi Bear | - | - | - | $479,351 | 96 | $2,295,065 | Jan 27 | Warner Bros. | false |
| 9 | Unstoppable | - | - | - | $433,276 | 53 | $495,173 | Jan 13 | 20th Century Fox International | false |
| 10 | Megamind | - | - | - | $401,542 | 95 | $2,864,778 | Dec 2 | Paramount Pictures International | false |
| 11 | Harry Potter and the Deathly Hallows: Part 1 | - | - | - | $315,870 | 117 | $5,864,306 | Nov 18 | Warner Bros. | false |
| 12 | Back to the Future Part II 2010 Re-release | - | - | - | $284,140 | 31 | $303,230 | Jan 13 | - | false |
| 13 | The Crazies | - | - | - | $252,055 | 21 | $280,365 | Jan 6 | - | false |
| 14 | Devil | - | - | - | $168,392 | 35 | $730,523 | Dec 2 | Universal Pictures International (UPI) | false |
| 15 | Love & Other Drugs | - | - | - | $148,935 | 45 | $460,956 | Jan 27 | 20th Century Fox International | false |
| 16 | Dorian Gray | - | - | - | $146,524 | 24 | $159,172 | Jan 13 | Distribution Company | false |
| 17 | Somewhere | - | - | - | $139,043 | 20 | $144,769 | Jan 13 | Universal Pictures International (UPI) | false |
| 18 | Burlesque | - | - | - | $131,340 | 31 | $132,781 | Jan 13 | Sony Pictures Releasing | false |
| 19 | The Silent House | - | - | - | $92,928 | 33 | $252,927 | Jan 27 | Distribution Company | false |
| 20 | The Illusionist | - | - | - | $87,229 | 14 | $148,313 | Dec 23 | - | false |
| 21 | Possession | - | - | - | $82,229 | 30 | $224,047 | Dec 16 | Distribution Company | false |
| 22 | I Spit on Your Grave | - | - | - | $54,980 | 18 | $62,694 | Jan 20 | Alfa Films | false |
| 23 | Paranormal Activity 2 | - | - | - | $54,291 | 59 | $2,481,483 | Nov 4 | Paramount Pictures International | false |
| 24 | Due Date | - | - | - | $52,865 | 47 | $938,241 | Nov 4 | Warner Bros. | false |
| 25 | Unthinkable | - | - | - | $50,764 | 19 | $179,084 | Dec 9 | Distribution Company | false |
| 26 | Baaria | - | - | - | $38,157 | 5 | $43,373 | Jan 13 | Alfa Films | false |
| 27 | 22 Bullets | - | - | - | $32,189 | 21 | $127,691 | Dec 9 | Alfa Films | false |
| 28 | Mother and Child | - | - | - | $30,247 | 15 | $52,955 | Jan 27 | Distribution Company | false |
| 29 | The Collector | - | - | - | $26,801 | 33 | $184,530 | Dec 9 | Impacto Cine | false |
| 30 | The Switch | - | - | - | $23,548 | 37 | $570,139 | Nov 11 | - | false |
| 31 | In the Beginning 2011 Re-release | - | - | - | $23,218 | 7 | $42,401 | Jan 27 | - | false |
| 32 | Skyline | - | - | - | $14,148 | 56 | $565,237 | Nov 25 | Distribution Company | false |
| 33 | Saw 3D | - | - | - | $12,822 | 71 | $1,467,534 | Oct 28 | - | false |
| 34 | Che: A New Man | - | - | - | $7,544 | 17 | $140,615 | Oct 7 | Distribution Company | false |
| 35 | Solomon Kane | - | - | - | $6,852 | 25 | $135,137 | Nov 25 | Alfa Films | false |
| 36 | Villa Amalia 2009 Re-release | - | - | - | $6,061 | 4 | $57,945 | Nov 11 | Alfa Films | false |
| 37 | Three Monkeys | - | - | - | $5,992 | 3 | $14,566 | Jan 27 | - | false |
| 38 | The Town | - | - | - | $3,917 | 45 | $677,594 | Oct 21 | Warner Bros. | false |
| 39 | Agora | - | - | - | $3,380 | 17 | $202,379 | Nov 4 | Distribution Company | false |
| 40 | The Dirty Saints | - | - | - | $3,337 | 1 | $4,198 | Jan 6 | Primer Plano Film Group | false |
| 41 | The Old Woman at the Back | - | - | - | $3,204 | 2 | $7,687 | Jan 20 | Primer Plano Film Group | false |
| 42 | Come Undone | - | - | - | $2,967 | 12 | $118,642 | Nov 18 | CDI Films | false |
| 43 | The Social Network | - | - | - | $2,925 | 51 | $621,292 | Oct 21 | Sony Pictures Releasing | false |
| 44 | Videocracy | - | - | - | $2,517 | 4 | $5,737 | Dec 23 | CDI Films | false |
| 45 | Love in Transit | - | - | - | $2,454 | 8 | $18,031 | Dec 2 | Primer Plano Film Group | false |
| 46 | The Kids Are All Right | - | - | - | $2,252 | 29 | $388,831 | Sep 30 | Alfa Films | false |
| 47 | Red | - | - | - | $2,078 | 54 | $691,246 | Oct 28 | Alfa Films | false |
| 48 | The Pursuer | - | - | - | $2,059 | 2 | $4,807 | Dec 9 | Primer Plano Film Group | false |
| 49 | Gaturro | - | - | - | $1,615 | 107 | $533,158 | Sep 9 | Distribution Company | false |
| 50 | Buen día, día | - | - | - | $1,160 | 1 | $1,131 | Jan 13 | Primer Plano Film Group | false |
| 51 | Eat Pray Love | - | - | - | $909 | 55 | $1,367,393 | Sep 16 | Sony Pictures Releasing | false |
| 52 | Machete | - | - | - | $800 | 32 | $187,600 | Nov 25 | Sony Pictures Releasing | false |
| 53 | The Last Exorcism | - | - | - | $460 | 43 | $1,144,364 | Sep 9 | - | false |
| 54 | Boca de fresa | - | - | - | $423 | 19 | $25,494 | Nov 11 | Primer Plano Film Group | false |
| 55 | Berlin Calling 2010 Re-release | - | - | - | $419 | 7 | $13,596 | Dec 16 | Impacto Cine | false |
| 56 | Life as We Know It | - | - | - | $89 | 43 | $650,507 | Oct 7 | Warner Bros. | false |
