| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Avatar | - | - | - | $6,244,483 | 196 | $15,866,546 | Dec 16 | 20th Century Fox International | false |
| 2 | Alvin and the Chipmunks: The Squeakquel | - | - | - | $2,150,335 | 93 | $4,461,871 | Dec 23 | 20th Century Fox International | false |
| 3 | Sherlock Holmes | - | - | - | $2,127,088 | 75 | $2,763,022 | Jan 6 | Warner Bros. | false |
| 4 | Dossier K. | - | - | - | $1,279,260 | 38 | $3,647,079 | Dec 9 | Kinepolis Film Distribution (KFD) | false |
| 5 | It's Complicated | - | - | - | $891,290 | 43 | $1,459,580 | Dec 23 | Universal Pictures International (UPI) | false |
| 6 | Mr. Nobody | - | - | - | $612,506 | 36 | $816,771 | Jan 13 | Belga Films | false |
| 7 | Cloudy with a Chance of Meatballs | - | - | - | $601,196 | 42 | $1,122,314 | Jan 13 | Sony Pictures Releasing | false |
| 8 | Up in the Air | - | - | - | $568,632 | 26 | $1,113,452 | Jan 20 | Universal Pictures International (UPI) | false |
| 9 | Plop en de kabouterbaby | - | - | - | $557,443 | 34 | $1,540,037 | Dec 9 | Kinepolis Film Distribution (KFD) | false |
| 10 | The Twilight Saga: New Moon | - | - | - | $528,211 | 91 | $6,142,938 | Nov 19 | Belga Films | false |
| 11 | Invictus | - | - | - | $518,776 | 25 | $738,223 | Jan 13 | Warner Bros. | false |
| 12 | Anubis en de wraak van Arghus | - | - | - | $413,187 | 30 | $1,053,397 | Dec 16 | Kinepolis Film Distribution (KFD) | false |
| 13 | Did You Hear About the Morgans? | - | - | - | $353,796 | 27 | $756,459 | Jan 27 | Sony Pictures Releasing | false |
| 14 | 2012 | - | - | - | $335,758 | 98 | $6,322,004 | Nov 11 | Sony Pictures Releasing | false |
| 15 | Arthur and the Revenge of Maltazard | - | - | - | $331,319 | 79 | $2,097,280 | Dec 2 | Belga Films | false |
| 16 | The Men Who Stare at Goats | - | - | - | $248,049 | 14 | $327,273 | Jan 6 | Kinepolis Film Distribution (KFD) | false |
| 17 | Paranormal Activity | - | - | - | $214,053 | 20 | $1,155,278 | Nov 25 | Kinepolis Film Distribution (KFD) | false |
| 18 | The Barons | - | - | - | $213,751 | 13 | $1,266,035 | Nov 4 | Cinéart | false |
| 19 | The Whistler | - | - | - | $208,125 | 13 | $211,103 | Jan 6 | Benelux Film Distributors | false |
| 20 | A Serious Man | - | - | - | $205,963 | 13 | $489,273 | Jan 20 | Universal Pictures International (UPI) | false |
| 21 | The Concert | - | - | - | $202,525 | 15 | $820,323 | Nov 11 | Cinéart | false |
| 22 | Oceans | - | - | - | $168,357 | 26 | $732,605 | Jan 27 | Alternative Films | false |
| 23 | A Christmas Carol | - | - | - | $146,627 | 66 | $1,769,393 | Nov 18 | Walt Disney Pictures | false |
| 24 | The Girl Who Played with Fire | - | - | - | $144,963 | 21 | $196,087 | Jan 13 | Benelux Film Distributors | false |
| 25 | The Road | - | - | - | $143,892 | 24 | $367,861 | Jan 27 | Benelux Film Distributors | false |
| 26 | Brothers | - | - | - | $138,605 | 19 | $313,467 | Dec 23 | A-Film Distribution | false |
| 27 | Oscar and the Lady in Pink | - | - | - | $134,031 | 24 | $325,322 | Dec 16 | Cinéart | false |
| 28 | Where the Wild Things Are | - | - | - | $110,622 | 20 | $117,817 | Dec 30 | Warner Bros. | false |
| 29 | Capitalism: A Love Story | - | - | - | $105,412 | 16 | $162,408 | Jan 6 | Paradiso Entertainment | false |
| 30 | Saw VI | - | - | - | $104,100 | 31 | $467,813 | Dec 23 | Les Films de l'Elysée | false |
| 31 | Das Lied der Dinge | - | - | - | $102,456 | 33 | $3,589,842 | Oct 7 | Kinepolis Film Distribution (KFD) | false |
| 32 | RTT | - | - | - | $76,383 | 18 | $392,762 | Dec 9 | Universal Pictures International (UPI) | false |
| 33 | Coco Chanel & Igor Stravinsky | - | - | - | $64,364 | 8 | $77,413 | Jan 6 | Cinéart | false |
| 34 | [Rec]² | - | - | - | $60,558 | 10 | $147,246 | Dec 23 | Cinéart | false |
| 35 | Couples Retreat | - | - | - | $58,450 | 28 | $506,707 | Dec 2 | Universal Pictures International (UPI) | false |
| 36 | Triangle | - | - | - | $52,732 | 8 | $53,130 | Dec 30 | Kinepolis Film Distribution (KFD) | false |
| 37 | Up | - | - | - | $49,221 | 132 | $7,088,865 | Oct 7 | Walt Disney Pictures | false |
| 38 | Bright Star | - | - | - | $41,991 | 7 | $133,313 | Dec 9 | Paradiso Entertainment | false |
| 39 | The Last Flight | - | - | - | $40,489 | 10 | $48,746 | Jan 6 | Belga Films | false |
| 40 | Altiplano | - | - | - | $38,950 | 6 | $154,835 | Nov 25 | - | false |
| 41 | Wolf | - | - | - | $30,533 | 10 | $110,750 | Dec 9 | Alternative Films | false |
| 42 | Eleanor's Secret | - | - | - | $30,014 | 14 | $104,285 | Dec 16 | Cinéart | false |
| 43 | Love Life | - | - | - | $28,861 | 7 | $148,415 | Dec 2 | Benelux Film Distributors | false |
| 44 | The Rebound | - | - | - | $18,819 | 27 | $356,704 | Nov 11 | Paradiso Entertainment | false |
| 45 | The White Ribbon | - | - | - | $17,420 | 17 | $497,190 | Oct 21 | Cinéart | false |
| 46 | Rapt | - | - | - | $16,927 | 6 | $86,811 | Dec 9 | Cinéart | false |
| 47 | Creation | - | - | - | $15,195 | 5 | $22,281 | Jan 20 | A-Film Distribution | false |
| 48 | The Ordinary People | - | - | - | $14,588 | 5 | $29,091 | Jan 20 | Cinéart | false |
| 49 | City Island | - | - | - | $13,502 | 9 | $23,930 | Jan 6 | Les Films de l'Elysée | false |
| 50 | No One Knows About Persian Cats | - | - | - | $11,702 | 6 | $56,739 | Jan 27 | Cinéart | false |
| 51 | The Informant! | - | - | - | $7,970 | 7 | $227,494 | Nov 18 | Warner Bros. | false |
| 52 | Samson & Delilah | - | - | - | $7,698 | 4 | $7,698 | Dec 30 | Cinéart | false |
| 53 | Hachi: A Dog's Tale | - | - | - | $6,665 | 5 | $38,085 | Dec 23 | Kinepolis Film Distribution (KFD) | false |
| 54 | Eyes Wide Open | - | - | - | $6,416 | 5 | $80,455 | Dec 2 | Cinéart | false |
| 55 | Little Nicholas | - | - | - | $4,918 | 30 | $1,905,136 | Sep 30 | Cinéart | false |
| 56 | John Rabe | - | - | - | $4,065 | 12 | $5,264 | Jan 20 | ABC Distribution | false |
| 57 | Remembering the Children | - | - | - | $898 | 7 | $16,814 | Dec 16 | Benelux Film Distributors | false |
| 58 | Krabat and the Legend of the Satanic Mill | - | - | - | $256 | 1 | $256 | Jan 27 | Jekino | false |
