| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Bedtime Stories | - | - | - | $7,356,688 | 600 | $8,783,222 | Jan 1 | Walt Disney Pictures | false |
| 2 | The Curious Case of Benjamin Button | - | - | - | $4,106,838 | 350 | $7,182,452 | Jan 16 | Warner Bros. | false |
| 3 | Rudo y Cursi | - | - | - | $3,676,747 | 505 | $8,357,502 | Dec 19 | Universal Pictures International (UPI) | false |
| 4 | Seven Pounds | - | - | - | $3,344,007 | 300 | $4,294,120 | Jan 9 | Sony Pictures Releasing | false |
| 5 | Bolt | - | - | - | $2,217,500 | 700 | $7,915,302 | Dec 19 | Walt Disney Pictures | false |
| 6 | Marley & Me | - | - | - | $2,179,069 | 390 | $2,695,991 | Jan 16 | 20th Century Fox International | false |
| 7 | Australia | - | - | - | $2,104,967 | 393 | $4,369,708 | Dec 25 | 20th Century Fox International | false |
| 8 | Volverte a ver | - | - | - | $1,466,029 | 337 | $2,372,222 | Dec 25 | Videocine | false |
| 9 | Hotel for Dogs | - | - | - | $1,271,809 | 369 | $3,484,506 | Jan 23 | Paramount Pictures International | false |
| 10 | The Day the Earth Stood Still | - | - | - | $846,349 | 804 | $9,562,903 | Dec 12 | 20th Century Fox International | false |
| 11 | The Tale of Despereaux | - | - | - | $830,942 | 540 | $2,297,403 | Dec 25 | Universal Pictures International (UPI) | false |
| 12 | Madagascar: Escape 2 Africa | - | - | - | $792,292 | 866 | $16,865,859 | Dec 5 | Paramount Pictures International | false |
| 13 | Four Christmases | - | - | - | $721,021 | 288 | $2,121,744 | Dec 19 | Gussi Films | false |
| 14 | Solstice | - | - | - | $528,405 | 119 | $1,285,521 | Dec 5 | Videocine | false |
| 15 | The Flock | - | - | - | $505,476 | 120 | $914,881 | Jan 9 | Videocine | false |
| 16 | Twilight | - | - | - | $454,430 | 580 | $9,842,699 | Nov 21 | Corazón Films | false |
| 17 | My Best Friend's Girl | - | - | - | $433,126 | 200 | $956,550 | Jan 23 | Videocine | false |
| 18 | Che: Part One | - | - | - | $373,236 | 150 | $576,566 | Jan 16 | Gussi Films | false |
| 19 | Vicky Cristina Barcelona | - | - | - | $244,439 | 145 | $952,422 | Dec 5 | Gussi Films | false |
| 20 | The Boy in the Striped Pajamas | - | - | - | $199,730 | 35 | $959,188 | Nov 28 | Walt Disney Pictures | false |
| 21 | The Spirit | - | - | - | $192,799 | 70 | $466,180 | Jan 23 | Sony Pictures Releasing | false |
| 22 | Death Defying Acts | - | - | - | $170,757 | 95 | $608,600 | Nov 21 | Gussi Films | false |
| 23 | RocknRolla | - | - | - | $156,983 | 80 | $234,268 | Jan 9 | Warner Bros. | false |
| 24 | Disaster Movie | - | - | - | $136,105 | 200 | $767,410 | Nov 28 | Gussi Films | false |
| 25 | The Women | - | - | - | $121,898 | 100 | $465,445 | Nov 28 | Universal Pictures International (UPI) | false |
| 26 | Sex Drive | - | - | - | $112,017 | 119 | $213,841 | Jan 23 | Corazón Films | false |
| 27 | Max & Co | - | - | - | $108,379 | 70 | $264,648 | Jan 16 | Star Films | false |
| 28 | Wild Child | - | - | - | $106,217 | 120 | $348,673 | Nov 28 | Paramount Pictures International | false |
| 29 | Penelope | - | - | - | $105,713 | 40 | $177,791 | Jan 9 | Gussi Films | false |
| 30 | Burn After Reading | - | - | - | $105,262 | 250 | $1,863,287 | Oct 24 | Universal Pictures International (UPI) | false |
| 31 | Nights in Rodanthe | - | - | - | $96,358 | 236 | $1,900,304 | Oct 3 | Warner Bros. | false |
| 32 | Mama's Boy | - | - | - | $92,748 | 101 | $199,489 | Dec 12 | Videocine | false |
| 33 | Lakeview Terrace | - | - | - | $89,711 | 50 | $295,116 | Nov 21 | Sony Pictures Releasing | false |
| 34 | Free Style | - | - | - | $89,157 | 198 | $276,917 | Dec 25 | 20th Century Fox International | false |
| 35 | The Duchess | - | - | - | $82,688 | 28 | $509,855 | Nov 21 | Paramount Pictures International | false |
| 36 | Appaloosa | - | - | - | $73,321 | 59 | $205,379 | Dec 12 | Gussi Films | false |
| 37 | Pride and Glory | - | - | - | $72,768 | 200 | $1,345,250 | Nov 7 | Gussi Films | false |
| 38 | The Edge of Heaven | - | - | - | $72,651 | 14 | $107,317 | Jan 9 | Alphaville | false |
| 39 | Grace Is Gone | - | - | - | $70,982 | 42 | $142,317 | Jan 23 | Gussi Films | false |
| 40 | Apartment 1303 | - | - | - | $55,517 | 40 | $282,838 | Oct 17 | Alphaville | false |
| 41 | Mr. Magorium's Wonder Emporium | - | - | - | $54,544 | 203 | $1,285,173 | Nov 7 | Zima Entertainment | false |
| 42 | Nick and Norah's Infinite Playlist | - | - | - | $52,937 | 75 | $200,548 | Dec 5 | Sony Pictures Releasing | false |
| 43 | The Good Night | - | - | - | $49,289 | 60 | $117,427 | Jan 16 | Videocine | false |
| 44 | Be Kind Rewind | - | - | - | $47,841 | 79 | $358,400 | Oct 31 | Videocine | false |
| 45 | Rogue | - | - | - | $45,059 | 50 | $381,975 | Sep 19 | Gussi Films | false |
| 46 | Body of Lies | - | - | - | $41,963 | 327 | $2,147,839 | Nov 28 | Warner Bros. | false |
| 47 | Private Fears in Public Places | - | - | - | $34,042 | 10 | $201,400 | Jun 27 | Alphaville | false |
| 48 | Molière | - | - | - | $34,030 | 20 | $182,993 | Sep 5 | Universal Pictures International (UPI) | false |
| 49 | Smart People | - | - | - | $32,035 | 20 | $67,984 | Jan 23 | Quality Films | false |
| 50 | Saw V | - | - | - | $29,549 | 120 | $1,029,677 | Oct 31 | Walt Disney Pictures | false |
| 51 | P | - | - | - | $25,981 | 28 | $86,834 | Dec 12 | Alphaville | false |
| 52 | Noodle | - | - | - | $23,708 | 11 | $94,743 | Dec 26 | Zima Entertainment | false |
| 53 | The Little Traitor | - | - | - | $23,142 | 16 | $52,393 | Jan 23 | - | false |
| 54 | Outlaw | - | - | - | $19,754 | 20 | $47,673 | Dec 12 | Quality Films | false |
| 55 | Du jour au lendemain 2009 Re-release | - | - | - | $18,147 | 12 | $23,162 | Jan 9 | Cinemas Nueva Era | false |
| 56 | Frozen River | - | - | - | $17,928 | 7 | $74,384 | Nov 7 | Sony Pictures Releasing | false |
| 57 | Kada kien su karma | - | - | - | $16,131 | 101 | $387,077 | Oct 10 | Universal Pictures International (UPI) | false |
| 58 | My Life Inside | - | - | - | $12,774 | 10 | $16,482 | Jan 16 | Canana Films | false |
| 59 | Funny Games | - | - | - | $11,082 | 45 | $265,499 | Sep 26 | Universal Pictures International (UPI) | false |
| 60 | The Unknown Woman | - | - | - | $9,977 | 14 | $107,052 | Nov 7 | Quality Films | false |
| 61 | Blonde and Blonder | - | - | - | $9,650 | 40 | $102,424 | Oct 3 | Quality Films | false |
| 62 | Dedication 2008 Re-release | - | - | - | $9,353 | 50 | $157,329 | Oct 10 | Quality Films | false |
| 63 | Satanás | - | - | - | $8,602 | 43 | $133,804 | Oct 31 | Gussi Films | false |
| 64 | Fly Me to the Moon 3D | - | - | - | $8,233 | 17 | $2,165,400 | Mar 9 | Gussi Films | false |
| 65 | Impy's Island | - | - | - | $7,748 | 74 | $415,245 | Nov 14 | Gussi Films | false |
| 66 | La capture | - | - | - | $7,574 | 13 | $80,624 | Oct 17 | - | false |
| 67 | The Ugly Duckling and Me! | - | - | - | $7,454 | 77 | $402,200 | Aug 29 | Quality Films | false |
| 68 | Balls of Fury | - | - | - | $7,254 | 50 | $105,855 | Nov 7 | Gussi Films | false |
| 69 | Acne | - | - | - | $7,160 | 12 | $32,279 | Dec 12 | David Distribucion | false |
| 70 | The Island 2008 Re-release | - | - | - | $6,898 | 9 | $32,675 | Dec 12 | Zima Entertainment | false |
| 71 | 24 Frames of Terror | - | - | - | $6,342 | 16 | $68,919 | Nov 14 | - | false |
| 72 | The Condemned | - | - | - | $5,959 | 68 | $222,054 | Oct 10 | Corazón Films | false |
| 73 | Swing Vote | - | - | - | $5,400 | 97 | $312,283 | Nov 7 | Quality Films | false |
| 74 | Death of a President | - | - | - | $5,093 | 9 | $76,000 | Jul 4 | Quality Films | false |
| 75 | Trivial | - | - | - | $4,018 | 14 | $59,176 | Feb 8 | - | false |
| 76 | The Last Legion | - | - | - | $3,625 | 80 | $897,002 | Aug 29 | Zima Entertainment | false |
| 77 | Pineapple Express | - | - | - | $3,154 | 50 | $148,200 | Oct 10 | Sony Pictures Releasing | false |
| 78 | Irina Palm | - | - | - | $3,140 | 11 | $260,615 | May 30 | Zima Entertainment | false |
| 79 | Espérame en otro mundo | - | - | - | $3,036 | 30 | $54,560 | Oct 24 | Videocine | false |
| 80 | Space Chimps | - | - | - | $2,897 | 200 | $669,602 | Oct 24 | Corazón Films | false |
| 81 | Quantum of Solace | - | - | - | $2,800 | 504 | $6,049,122 | Nov 14 | Sony Pictures Releasing | false |
| 82 | Honeydripper | - | - | - | $2,696 | 10 | $14,447 | Oct 10 | David Distribucion | false |
| 83 | My Brother 2008 Re-release | - | - | - | $2,214 | 17 | $84,690 | Nov 7 | - | false |
| 84 | WALL·E | - | - | - | $1,947 | 790 | $17,679,805 | Jul 4 | Walt Disney Pictures | false |
| 85 | A Soap 2008 Re-release | - | - | - | $1,929 | 6 | $34,958 | Oct 17 | Alphaville | false |
| 86 | Charlie Bartlett | - | - | - | $1,898 | 80 | $134,229 | Oct 3 | Azteca Films | false |
| 87 | The Last Mistress | - | - | - | $1,879 | 4 | $22,885 | Nov 28 | Cinemas Nueva Era | false |
| 88 | Intimate Stories 2009 Re-release | - | - | - | $1,834 | 1 | $5,061 | Jan 16 | Alphaville | false |
| 89 | Caramel | - | - | - | $1,629 | 14 | $97,809 | Sep 26 | Zima Entertainment | false |
| 90 | 4 Months, 3 Weeks and 2 Days | - | - | - | $1,564 | 12 | $143,501 | Apr 18 | Zima Entertainment | false |
| 91 | An American Crime | - | - | - | $1,531 | 50 | $587,884 | Aug 8 | Quality Films | false |
| 92 | The Air I Breathe | - | - | - | $1,506 | 142 | $759,020 | Oct 17 | Videocine | false |
| 93 | Pamela por amor | - | - | - | $1,471 | 15 | $99,016 | Sep 5 | - | false |
| 94 | Íntimamente entre amigas | - | - | - | $1,459 | 9 | $21,976 | Sep 19 | - | false |
| 95 | The Killing Gene | - | - | - | $1,431 | 73 | $155,775 | Oct 31 | Quality Films | false |
| 96 | Spam | - | - | - | $1,425 | 225 | $507,148 | Oct 24 | Corazón Films | false |
| 97 | Summer '04 | - | - | - | $1,103 | 8 | $41,566 | May 9 | Cinemas Nueva Era | false |
| 98 | Timbiriche: La misma piedra | - | - | - | $1,046 | 28 | $25,488 | Nov 28 | Alphaville | false |
| 99 | Dinosaurs: Giants of Patagonia | - | - | - | $1,003 | 1 | $60,099 | - | Distribution Company | false |
| 100 | Adrift in Manhattan | - | - | - | $967 | 23 | $88,173 | Jun 6 | - | false |
| 101 | Grill Point 2008 Re-release | - | - | - | $913 | 2 | $2,715 | Nov 3 | MAC Releasing | false |
| 102 | Lights in the Dusk | - | - | - | $903 | 1 | $4,418 | Jan 2 | - | false |
| 103 | Sleuth | - | - | - | $893 | 6 | $201,890 | Jan 25 | Sony Pictures Releasing | false |
| 104 | Tideland | - | - | - | $823 | 2 | $19,103 | Oct 10 | - | false |
| 105 | Deception | - | - | - | $716 | 98 | $331,631 | Nov 7 | Corazón Films | false |
| 106 | Ira & Abby | - | - | - | $676 | 40 | $244,002 | May 9 | Corazón Films | false |
| 107 | Nesio | - | - | - | $668 | 12 | $14,714 | Oct 24 | Film House | false |
| 108 | Lake Tahoe | - | - | - | $656 | 13 | $35,310 | Nov 28 | - | false |
| 109 | Promised Land | - | - | - | $579 | 4 | $25,280 | Mar 14 | Alphaville | false |
| 110 | Unrest | - | - | - | $543 | 40 | $931,993 | Mar 28 | - | false |
| 111 | Arresto domiciliario | - | - | - | $458 | 14 | $8,971 | Dec 5 | Corazón Films | false |
| 112 | The Bank Job | - | - | - | $425 | 81 | $1,806,999 | Aug 29 | Gussi Films | false |
| 113 | Raising Flagg 2008 Re-release | - | - | - | $412 | 14 | $33,199 | Apr 25 | - | false |
| 114 | Belle toujours 2008 Re-release | - | - | - | $346 | 2 | $8,771 | Oct 3 | Cinemas Nueva Era | false |
| 115 | Joy Division | - | - | - | $319 | 1 | $4,810 | Oct 17 | Canana Films | false |
| 116 | The House Bunny | - | - | - | $318 | 225 | $1,485,699 | Oct 24 | Sony Pictures Releasing | false |
| 117 | The Wedding Weekend | - | - | - | $317 | 3 | $5,373 | Apr 25 | Zima Entertainment | false |
| 118 | Valentino y el clan del can | - | - | - | $307 | 50 | $196,590 | Aug 8 | Azteca Films | false |
| 119 | One Missed Call | - | - | - | $251 | 242 | $3,414,400 | Mar 20 | Warner Bros. | false |
| 120 | Step Brothers | - | - | - | $243 | 100 | $710,254 | Sep 26 | Sony Pictures Releasing | false |
| 121 | Tear This Heart Out | - | - | - | $207 | 500 | $9,042,087 | Sep 12 | 20th Century Fox International | false |
| 122 | You, the Living | - | - | - | $193 | 2 | $12,611 | Sep 26 | MAC Releasing | false |
| 123 | The Strangers | - | - | - | $179 | 194 | $2,853,234 | Sep 19 | Videocine | false |
| 124 | Reservation Road | - | - | - | $169 | 20 | $109,622 | Aug 22 | Zima Entertainment | false |
| 125 | Runaways | - | - | - | $149 | 12 | $2,124 | Dec 5 | - | false |
| 126 | College Road Trip | - | - | - | $145 | 150 | $2,862,598 | Aug 8 | Walt Disney Pictures | false |
| 127 | The Host | - | - | - | $137 | 39 | $157,501 | Sep 5 | Gussi Films | false |
| 128 | Beverly Hills Chihuahua | - | - | - | $129 | 450 | $7,660,801 | Oct 3 | Walt Disney Pictures | false |
| 129 | Donkey Xote | - | - | - | $126 | 222 | $2,540,000 | Sep 12 | Videocine | false |
| 130 | Priceless | - | - | - | $106 | 25 | $373,412 | Apr 25 | Quality Films | false |
| 131 | Kurt Cobain About a Son 2008 Re-release | - | - | - | $89 | 1 | $4,107 | Dec 12 | Alphaville | false |
| 132 | Quatre étoiles 2008 Re-release | - | - | - | $87 | 12 | $23,787 | Aug 22 | Cinemas Nueva Era | false |
| 133 | The Bubble | - | - | - | $84 | 15 | $70,071 | Aug 1 | Alphaville | false |
| 134 | Never Back Down | - | - | - | $72 | 140 | $331,144 | Aug 22 | Corazón Films | false |
| 135 | The Big Sellout | - | - | - | $60 | 40 | $20,331 | Jun 13 | Canana Films | false |
| 136 | High School Musical 3: Senior Year | - | - | - | $54 | 535 | $4,396,904 | Oct 31 | Walt Disney Pictures | false |
| 137 | Mamma Mia! | - | - | - | $50 | 358 | $3,133,862 | Sep 12 | Universal Pictures International (UPI) | false |
| 138 | Harold & Kumar Escape from Guantanamo Bay | - | - | - | $47 | 60 | $173,401 | Aug 22 | Gussi Films | false |
