| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Madagascar: Escape 2 Africa | - | - | - | $2,042,777 | 116 | $6,565,460 | Dec 3 | Universal Pictures International (UPI) | false |
| 2 | Yes Man | - | - | - | $1,967,537 | 102 | $2,112,042 | Dec 31 | Warner Bros. | false |
| 3 | Loft | - | - | - | $1,663,698 | 322 | $9,168,516 | Oct 22 | Independent Films | false |
| 4 | Twilight | - | - | - | $1,335,920 | 54 | $3,294,541 | Nov 26 | Belga Films | false |
| 5 | De l'autre côté du lit | - | - | - | $981,120 | 28 | $1,220,695 | Jan 7 | Belga Films | false |
| 6 | Australia | - | - | - | $898,818 | 102 | $1,726,568 | Dec 17 | 20th Century Fox International | false |
| 7 | Seven Pounds | - | - | - | $740,354 | 30 | $949,850 | Jan 14 | Sony Pictures Releasing | false |
| 8 | Revolutionary Road | - | - | - | $630,309 | 43 | $1,017,408 | Jan 21 | Universal Pictures International (UPI) | false |
| 9 | Valkyrie | - | - | - | $628,528 | 75 | $1,926,066 | Jan 28 | 20th Century Fox International | false |
| 10 | Slumdog Millionaire | - | - | - | $613,648 | 40 | $3,794,750 | Jan 14 | Cinéart | false |
| 11 | Burn After Reading | - | - | - | $613,049 | 35 | $1,601,111 | Dec 10 | Universal Pictures International (UPI) | false |
| 12 | The Day the Earth Stood Still | - | - | - | $605,485 | 85 | $1,939,964 | Dec 10 | 20th Century Fox International | false |
| 13 | Bedtime Stories | - | - | - | $579,986 | 55 | $961,701 | Dec 24 | Walt Disney Pictures | false |
| 14 | Transporter 3 | - | - | - | $499,890 | 28 | $1,284,778 | Dec 10 | Belga Films | false |
| 15 | The Duchess | - | - | - | $431,887 | 30 | $458,360 | Jan 7 | Cinéart | false |
| 16 | Mamma Mia! | - | - | - | $400,880 | 60 | $3,879,680 | Sep 10 | Universal Pictures International (UPI) | false |
| 17 | High School Musical 3: Senior Year | - | - | - | $371,696 | 71 | $2,848,130 | Oct 29 | Walt Disney Pictures | false |
| 18 | The Flight Before Christmas | - | - | - | $347,569 | 34 | $648,220 | Dec 17 | Kinepolis Film Distribution (KFD) | false |
| 19 | Two Lovers | - | - | - | $298,586 | 14 | $485,054 | Dec 25 | Cinéart | false |
| 20 | The Heir Apparent: Largo Winch | - | - | - | $281,575 | 18 | $614,300 | Dec 17 | Cinéart | false |
| 21 | Piet Piraat en het zwaard van Zilvertand | - | - | - | $266,611 | 32 | $601,808 | Dec 10 | Kinepolis Film Distribution (KFD) | false |
| 22 | Trouble at Timpetill | - | - | - | $247,847 | 16 | $539,856 | Dec 17 | Alternative Films | false |
| 23 | Beauties at War | - | - | - | $245,090 | 18 | $384,471 | Jan 14 | Belga Films | false |
| 24 | Changeling | - | - | - | $187,074 | 33 | $969,755 | Nov 12 | Universal Pictures International (UPI) | false |
| 25 | Anubis en het Pad der 7 Zonden | - | - | - | $176,553 | 31 | $1,510,876 | Oct 15 | Kinepolis Film Distribution (KFD) | false |
| 26 | Saw V | - | - | - | $175,861 | 34 | $665,938 | Dec 17 | Les Films de l'Elysée | false |
| 27 | Vicky Cristina Barcelona | - | - | - | $156,893 | 28 | $1,151,236 | Oct 29 | Cinéart | false |
| 28 | Four Christmases | - | - | - | $151,493 | 25 | $397,149 | Dec 24 | Warner Bros. | false |
| 29 | Winter in Wartime | - | - | - | $147,012 | 15 | $359,538 | Dec 3 | Benelux Film Distributors | false |
| 30 | Blinker en de blixvaten | - | - | - | $122,456 | 34 | $274,756 | Dec 17 | Kinepolis Film Distribution (KFD) | false |
| 31 | Frost/Nixon | - | - | - | $122,447 | 20 | $143,328 | Jan 14 | Universal Pictures International (UPI) | false |
| 32 | Body of Lies | - | - | - | $107,591 | 50 | $895,108 | Nov 19 | Warner Bros. | false |
| 33 | Quantum of Solace | - | - | - | $105,535 | 97 | $4,745,885 | Nov 5 | Sony Pictures Releasing | false |
| 34 | Wild Child | - | - | - | $96,071 | 16 | $196,472 | Dec 24 | Universal Pictures International (UPI) | false |
| 35 | Afterwards | - | - | - | $84,798 | 11 | $88,415 | Jan 14 | Victory Productions | false |
| 36 | Special Correspondents | - | - | - | $79,810 | 16 | $91,333 | Jan 21 | Victory Productions | false |
| 37 | Christmas in Paris | - | - | - | $79,530 | 20 | $229,487 | Dec 17 | Kinepolis Film Distribution (KFD) | false |
| 38 | Appaloosa | - | - | - | $77,402 | 9 | $96,729 | Jan 7 | Paradiso Entertainment | false |
| 39 | The Women | - | - | - | $74,553 | 17 | $192,413 | Jan 28 | Belga Films | false |
| 40 | Il Divo | - | - | - | $71,725 | 9 | $83,537 | Jan 14 | ABC Distribution | false |
| 41 | Anything for Her | - | - | - | $71,720 | 13 | $76,712 | Dec 31 | Benelux Film Distributors | false |
| 42 | Eden Lake | - | - | - | $71,396 | 7 | $87,980 | Jan 21 | Benelux Film Distributors | false |
| 43 | Dirty Mind | - | - | - | $69,723 | 18 | $204,933 | Jan 28 | Kinepolis Film Distribution (KFD) | false |
| 44 | Pride and Glory | - | - | - | $68,834 | 19 | $232,638 | Dec 3 | Kinepolis Film Distribution (KFD) | false |
| 45 | Louise hires a contract killer | - | - | - | $65,817 | 14 | $129,978 | Dec 24 | Les Films de l'Elysée | false |
| 46 | The Visitor | - | - | - | $60,503 | 12 | $143,392 | Dec 17 | - | false |
| 47 | Agathe Cléry | - | - | - | $57,395 | 13 | $305,117 | Dec 3 | Alternative Films | false |
| 48 | Welcome to the Sticks | - | - | - | $56,458 | 64 | $10,746,995 | Feb 27 | Alternative Films | false |
| 49 | The Broken | - | - | - | $45,985 | 5 | $107,759 | Jan 14 | Paradiso Entertainment | false |
| 50 | Private Lessons | - | - | - | $45,396 | 9 | $75,325 | Jan 21 | Cinéart | false |
| 51 | The Silent Army | - | - | - | $43,593 | 11 | $135,808 | Dec 17 | - | false |
| 52 | Incendiary | - | - | - | $40,061 | 12 | $40,284 | Jan 7 | Kinepolis Film Distribution (KFD) | false |
| 53 | Public Enemy | - | - | - | $36,519 | 21 | $317,492 | Nov 19 | Kinepolis Film Distribution (KFD) | false |
| 54 | Elite Squad | - | - | - | $33,175 | 9 | $50,675 | Jan 21 | Benelux Film Distributors | false |
| 55 | Elegy | - | - | - | $31,089 | 49 | $181,282 | Oct 22 | Kinepolis Film Distribution (KFD) | false |
| 56 | Modern Life | - | - | - | $21,669 | 4 | $58,184 | Nov 5 | Benelux Film Distributors | false |
| 57 | A Man and His Dog | - | - | - | $20,658 | 9 | $25,089 | Jan 21 | Les Films de l'Elysée | false |
| 58 | Stella | - | - | - | $19,499 | 6 | $32,909 | Jan 14 | Benelux Film Distributors | false |
| 59 | The Wave | - | - | - | $14,359 | 12 | $55,560 | Oct 22 | Paradiso Entertainment | false |
| 60 | W. | - | - | - | $14,332 | 13 | $139,848 | Oct 29 | Paradiso Entertainment | false |
| 61 | Diamond 13 | - | - | - | $12,487 | 9 | $15,925 | Jan 28 | Les Films de l'Elysée | false |
| 62 | A Pain in the Ass | - | - | - | $11,446 | 22 | $78,203 | Dec 10 | Benelux Film Distributors | false |
| 63 | Hunger | - | - | - | $10,072 | 6 | $42,936 | Nov 12 | Paradiso Entertainment | false |
| 64 | Home | - | - | - | $9,387 | 6 | $56,968 | Nov 12 | Benelux Film Distributors | false |
| 65 | Quiet Chaos | - | - | - | $9,148 | 11 | $87,986 | Dec 3 | Cinéart | false |
| 66 | The Class | - | - | - | $8,753 | 33 | $895,100 | Oct 1 | Cinéart | false |
| 67 | Journey to the Center of the Earth | - | - | - | $8,042 | 11 | $291,893 | Nov 12 | Warner Bros. | false |
| 68 | Secret Defense | - | - | - | $7,613 | 8 | $58,709 | Dec 17 | Les Films de l'Elysée | false |
| 69 | Les grandes personnes | - | - | - | $6,263 | 7 | $6,428 | Jan 25 | - | false |
| 70 | Factory Girl | - | - | - | $5,806 | 8 | $5,806 | Jan 7 | - | false |
| 71 | Moscow, Belgium | - | - | - | $5,579 | 20 | $1,898,002 | Jan 30 | Kinepolis Film Distribution (KFD) | false |
| 72 | O'Horten | - | - | - | $4,034 | 4 | $4,730 | Jan 28 | Centre national du cinéma et de l'image animée (CNC) | false |
| 73 | The Baader Meinhof Complex | - | - | - | $3,845 | 11 | $36,966 | Jan 28 | A-Film Distribution | false |
| 74 | Ghajini | - | - | - | $3,740 | 2 | $22,708 | Dec 25 | - | false |
| 75 | The Edge of Love | - | - | - | $3,559 | 2 | $16,851 | Nov 26 | Belga Films | false |
| 76 | Religulous | - | - | - | $2,456 | 4 | $5,934 | Jan 21 | A-Film Distribution | false |
| 77 | Son of Rambow | - | - | - | $1,861 | 5 | $5,369 | Dec 24 | Universal Pictures International (UPI) | false |
| 78 | The Beautiful Person | - | - | - | $1,619 | 1 | $2,475 | Jan 7 | Centre national du cinéma et de l'image animée (CNC) | false |
| 79 | The Hessen Conspiracy | - | - | - | $1,569 | 4 | $1,569 | Jan 14 | - | false |
| 80 | Space Chimps | - | - | - | $1,296 | 52 | $1,200,452 | Oct 22 | Belga Films | false |
| 81 | The House Bunny | - | - | - | $875 | 3 | $36,672 | Dec 17 | Sony Pictures Releasing | false |
| 82 | A Wonderful Night in Split | - | - | - | $427 | 1 | $427 | Jan 21 | - | false |
| 83 | Nowhere Man | - | - | - | $416 | 8 | $26,213 | Nov 26 | Kinepolis Film Distribution (KFD) | false |
| 84 | SOS: Summer of Suspense | - | - | - | $18 | 1 | $18 | Jan 28 | Jekino | false |
