| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | The Day the Earth Stood Still | - | - | - | $1,886,078 | 122 | $2,100,530 | Jan 1 | 20th Century Fox International | false |
| 2 | Twilight | - | - | - | $1,750,999 | 88 | $1,844,290 | Jan 1 | Alfa Films | false |
| 3 | Bolt | - | - | - | $1,638,237 | 121 | $2,103,777 | Jan 15 | Walt Disney Pictures | false |
| 4 | Madagascar: Escape 2 Africa | - | - | - | $1,121,413 | 156 | $5,066,136 | Dec 4 | Paramount Pictures International | false |
| 5 | Yes Man | - | - | - | $809,109 | 58 | $1,324,861 | Jan 15 | Warner Bros. | false |
| 6 | El ratón Pérez 2 | - | - | - | $705,434 | 98 | $704,487 | Jan 1 | Walt Disney Pictures | false |
| 7 | Australia | - | - | - | $705,197 | 64 | $856,824 | Jan 8 | 20th Century Fox International | false |
| 8 | Changeling | - | - | - | $471,185 | 47 | $890,990 | Jan 22 | Universal Pictures International (UPI) | false |
| 9 | Marley & Me | - | - | - | $408,918 | 59 | $637,908 | Jan 22 | 20th Century Fox International | false |
| 10 | Doubt | - | - | - | $364,980 | 30 | $538,725 | Jan 15 | Walt Disney Pictures | false |
| 11 | Rudo y Cursi | - | - | - | $300,819 | 45 | $310,389 | Jan 8 | United International Pictures | false |
| 12 | Inkheart | - | - | - | $157,719 | 48 | $365,145 | Jan 29 | Distribution Company | false |
| 13 | Four Christmases | - | - | - | $148,511 | 41 | $419,584 | Dec 18 | Distribution Company | false |
| 14 | Body of Lies | - | - | - | $131,642 | 49 | $930,022 | Nov 27 | Warner Bros. | false |
| 15 | Revolutionary Road | - | - | - | $113,459 | 31 | $290,486 | Jan 29 | Paramount Pictures International | false |
| 16 | Bangkok Dangerous | - | - | - | $102,633 | 31 | $125,330 | Jan 15 | Distribution Company | false |
| 17 | The Spirit | - | - | - | $86,048 | 26 | $108,192 | Jan 22 | Sony Pictures Releasing | false |
| 18 | The Duchess | - | - | - | $79,379 | 15 | $263,387 | Dec 11 | United International Pictures | false |
| 19 | W. | - | - | - | $61,417 | 13 | $65,346 | Jan 15 | Impacto Cine | false |
| 20 | High School Musical 3: Senior Year | - | - | - | $60,381 | 124 | $1,314,788 | Nov 27 | Walt Disney Pictures | false |
| 21 | Asterix at the Olympic Games | - | - | - | $47,523 | 34 | $47,752 | Jan 8 | Distribution Company | false |
| 22 | Quarantine | - | - | - | $46,038 | 30 | $376,330 | Dec 4 | Sony Pictures Releasing | false |
| 23 | Righteous Kill | - | - | - | $40,553 | 44 | $580,788 | Nov 20 | CDI Films | false |
| 24 | Che: Part One | - | - | - | $30,047 | 56 | $669,305 | Nov 13 | Alfa Films | false |
| 25 | The Pope's Toilet | - | - | - | $27,667 | 7 | $28,065 | Jan 1 | Primer Plano Film Group | false |
| 26 | Ben X | - | - | - | $27,023 | 20 | $27,023 | Jan 1 | Distribution Company | false |
| 27 | Blame it on Fidel | - | - | - | $22,066 | 7 | $38,824 | Jan 22 | Zeta Films | false |
| 28 | Sex Drive | - | - | - | $21,817 | 29 | $34,790 | Jan 29 | Alfa Films | false |
| 29 | Saw V | - | - | - | $19,745 | 62 | $1,076,755 | Oct 30 | Walt Disney Pictures | false |
| 30 | Death Sentence | - | - | - | $19,476 | 36 | $186,418 | Dec 4 | Distribution Company | false |
| 31 | Quantum of Solace | - | - | - | $18,699 | 124 | $1,280,370 | Nov 6 | Sony Pictures Releasing | false |
| 32 | RocknRolla | - | - | - | $18,512 | 15 | $92,024 | Dec 11 | Warner Bros. | false |
| 33 | Late Bloomers | - | - | - | $16,133 | 7 | $77,398 | Nov 27 | Primer Plano Film Group | false |
| 34 | The Tracker 2008 Re-release | - | - | - | $13,521 | 5 | $168,175 | Dec 25 | IFA | false |
| 35 | Tear This Heart Out | - | - | - | $12,990 | 7 | $57,357 | Nov 27 | 20th Century Fox International | false |
| 36 | Planet Terror | - | - | - | $12,775 | 24 | $94,001 | Dec 11 | Pachamama Cine | false |
| 37 | Emma's Bliss | - | - | - | $10,043 | 5 | $26,523 | Jan 29 | Primer Plano Film Group | false |
| 38 | The Bank Job | - | - | - | $9,819 | 34 | $625,583 | Oct 16 | Alfa Films | false |
| 39 | Bella | - | - | - | $9,196 | 8 | $31,226 | Dec 25 | CDI Films | false |
| 40 | The Boy in the Striped Pajamas | - | - | - | $8,612 | 13 | $86,300 | Dec 4 | Walt Disney Pictures | false |
| 41 | Flawless | - | - | - | $7,808 | 24 | $256,910 | Nov 6 | Distribution Company | false |
| 42 | Journey to the Center of the Earth | - | - | - | $7,349 | 55 | $1,311,200 | Jul 17 | Distribution Company | false |
| 43 | Elegy | - | - | - | $7,164 | 22 | $175,398 | Nov 20 | Distribution Company | false |
| 44 | Aniceto | - | - | - | $6,815 | 32 | $134,481 | Jun 12 | Primer Plano Film Group | false |
| 45 | Deception | - | - | - | $6,739 | 13 | $68,776 | Dec 11 | Alfa Films | false |
| 46 | Fly Me to the Moon 3D | - | - | - | $6,563 | 45 | $31,665 | Dec 18 | Distribution Company | false |
| 47 | Bug | - | - | - | $6,194 | 3 | $6,619 | Jan 15 | Alfa Films | false |
| 48 | My Mom's New Boyfriend | - | - | - | $5,361 | 20 | $147,254 | Nov 13 | - | false |
| 49 | Fados | - | - | - | $3,259 | 6 | $37,153 | Nov 27 | Distribution Company | false |
| 50 | Death Defying Acts | - | - | - | $3,158 | 29 | $115,845 | Nov 27 | Alfa Films | false |
| 51 | Red Like the Sky 2008 Re-release | - | - | - | $3,016 | 4 | $24,514 | Dec 4 | Primer Plano Film Group | false |
| 52 | Ira & Abby | - | - | - | $2,585 | 13 | $44,301 | Dec 11 | CDI Films | false |
| 53 | Manual of Love 2008 Re-release | - | - | - | $2,121 | 9 | $136,530 | Sep 25 | Notro Films | false |
| 54 | Four Minutes | - | - | - | $1,624 | 14 | $159,960 | Aug 28 | Alfa Films | false |
| 55 | Café de los maestros | - | - | - | $1,019 | 8 | $94,126 | Jun 26 | Alfa Films | false |
| 56 | My Brother is an Only Child | - | - | - | $954 | 13 | $222,886 | Sep 18 | Alfa Films | false |
| 57 | La leyenda | - | - | - | $884 | 48 | $206,591 | Nov 20 | United International Pictures | false |
| 58 | The Magic Flute | - | - | - | $849 | 10 | $27,214 | Oct 23 | Distribution Company | false |
| 59 | Days of Darkness | - | - | - | $731 | 4 | $15,773 | Oct 16 | Alfa Films | false |
| 60 | Max Payne | - | - | - | $612 | 31 | $165,343 | Nov 20 | 20th Century Fox International | false |
| 61 | Two Friends and a Burglar | - | - | - | $597 | 4 | $10,128 | Nov 27 | Primer Plano Film Group | false |
| 62 | Shara | - | - | - | $468 | 7 | $44,065 | Oct 30 | Zeta Films | false |
| 63 | Black Christmas | - | - | - | $308 | 26 | $95,544 | Nov 13 | Distribution Company | false |
| 64 | Nights in Rodanthe | - | - | - | $182 | 49 | $879,399 | Oct 2 | Warner Bros. | false |
| 65 | The Camera Obscura 2008 Re-release | - | - | - | $132 | 10 | $64,009 | Oct 16 | Distribution Company | false |
| 66 | Tropic Thunder | - | - | - | $92 | 48 | $1,349,571 | Sep 4 | United International Pictures | false |
