| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | National Treasure: Book of Secrets | - | - | - | $432,949 | 89 | $1,392,475 | Jan 11 | Ster-Kinekor Pictures | false |
| 2 | Saw IV | - | - | - | $195,238 | 40 | $285,231 | Jan 18 | Ster-Kinekor Pictures | false |
| 3 | The Bucket List | - | - | - | $184,630 | 40 | $579,526 | Jan 25 | NuMetro Distribution | false |
| 4 | Good Luck Chuck | - | - | - | $139,430 | 31 | $398,763 | Jan 25 | United International Pictures | false |
| 5 | Elizabeth: The Golden Age | - | - | - | $139,288 | 38 | $198,102 | Jan 18 | United International Pictures | false |
| 6 | I Am Legend | - | - | - | $115,420 | 66 | $1,804,583 | Dec 28 | NuMetro Distribution | false |
| 7 | Alvin and the Chipmunks | - | - | - | $84,863 | 53 | $1,000,576 | Dec 28 | NuMetro Distribution | false |
| 8 | Griffin & Phoenix | - | - | - | $65,606 | 33 | $65,606 | Jan 18 | NuMetro Distribution | false |
| 9 | We Own the Night | - | - | - | $64,915 | 57 | $466,838 | Jan 4 | United International Pictures | false |
| 10 | Martian Child | - | - | - | $49,989 | 25 | $58,528 | Jan 18 | NuMetro Distribution | false |
| 11 | Arthur and the Invisibles | - | - | - | $42,197 | 30 | $96,579 | Jan 25 | Ster-Kinekor Pictures | false |
| 12 | The Jane Austen Book Club | - | - | - | $41,979 | 12 | $192,946 | Jan 4 | Ster-Kinekor Pictures | false |
| 13 | August Rush | - | - | - | $31,441 | 16 | $309,373 | Dec 28 | NuMetro Distribution | false |
| 14 | Enchanted | - | - | - | $28,951 | 68 | $1,350,585 | Dec 21 | Ster-Kinekor Pictures | false |
| 15 | Gone Baby Gone | - | - | - | $26,012 | 8 | $35,791 | Jan 25 | Ster-Kinekor Pictures | false |
| 16 | Aliens vs. Predator: Requiem | - | - | - | $23,406 | 32 | $264,562 | Jan 4 | NuMetro Distribution | false |
| 17 | Into the Wild | - | - | - | $22,029 | 10 | $76,891 | Jan 25 | United International Pictures | false |
| 18 | La Vie En Rose | - | - | - | $21,213 | 6 | $161,011 | Dec 14 | Ster-Kinekor Pictures | false |
| 19 | Talk to Me | - | - | - | $18,567 | 26 | $45,522 | Jan 25 | United International Pictures | false |
| 20 | The Darjeeling Limited | - | - | - | $17,568 | 12 | $17,568 | Jan 18 | NuMetro Distribution | false |
| 21 | Evening | - | - | - | $15,029 | 16 | $76,723 | Jan 11 | Ster-Kinekor Pictures | false |
| 22 | The Heartbreak Kid | - | - | - | $14,974 | 62 | $912,922 | Nov 16 | United International Pictures | false |
| 23 | This Christmas | - | - | - | $12,800 | 10 | $200,685 | Dec 21 | Ster-Kinekor Pictures | false |
| 24 | Hitman | - | - | - | $10,814 | 41 | $702,662 | Dec 14 | NuMetro Distribution | false |
| 25 | Underdog | - | - | - | $8,118 | 9 | $58,734 | Jan 4 | Ster-Kinekor Pictures | false |
| 26 | Like Stars on Earth | - | - | - | $7,267 | 5 | $79,506 | Dec 21 | Ster-Kinekor Pictures | false |
| 27 | American Gangster | - | - | - | $1,038 | 52 | $797,557 | Dec 7 | United International Pictures | false |
| 28 | The Kingdom | - | - | - | $668 | 47 | $489,968 | Nov 9 | United International Pictures | false |
| 29 | Surf's Up | - | - | - | $602 | 75 | $1,189,456 | Nov 30 | Ster-Kinekor Pictures | false |
| 30 | Daddy Day Camp | - | - | - | $220 | 10 | $196,873 | Oct 5 | Ster-Kinekor Pictures | false |
| 31 | 3:10 to Yuma | - | - | - | $157 | 10 | $77,264 | Nov 2 | Ster-Kinekor Pictures | false |
