| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | I Am Legend | - | - | - | $19,040,306 | 506 | $21,020,300 | Jan 11 | Warner Bros. | false |
| 2 | L'allenatore nel pallone 2 | - | - | - | $11,044,319 | 510 | $11,225,448 | Jan 11 | Medusa Distribuzione | false |
| 3 | American Gangster | - | - | - | $10,296,683 | 457 | $15,520,131 | Jan 18 | Universal Pictures International (UPI) | false |
| 4 | Sorry, If I Love You | - | - | - | $9,428,720 | 508 | $20,913,254 | Jan 25 | Medusa Distribuzione | false |
| 5 | Natale in crociera | - | - | - | $9,208,448 | 581 | $36,800,000 | Dec 14 | Filmauro | false |
| 6 | A Beautiful Wife | - | - | - | $8,500,660 | 546 | $29,502,958 | Dec 14 | Medusa Distribuzione | false |
| 7 | Black and White | - | - | - | $6,606,560 | 301 | $8,096,913 | Jan 11 | 01 Distribution | false |
| 8 | National Treasure: Book of Secrets | - | - | - | $5,800,959 | 348 | $13,168,731 | Dec 21 | Walt Disney Pictures | false |
| 9 | Lions for Lambs | - | - | - | $4,474,189 | 189 | $8,321,849 | Dec 21 | 20th Century Fox International | false |
| 10 | The Golden Compass | - | - | - | $4,244,196 | 379 | $13,784,599 | Dec 14 | 01 Distribution | false |
| 11 | Alvin and the Chipmunks | - | - | - | $3,957,654 | 256 | $5,481,266 | Jan 18 | 20th Century Fox International | false |
| 12 | Bee Movie | - | - | - | $3,854,080 | 368 | $9,595,892 | Dec 21 | Universal Pictures International (UPI) | false |
| 13 | Halloween | - | - | - | $3,418,936 | 236 | $3,418,936 | Jan 4 | Lucky Red | false |
| 14 | Love in the Time of Cholera | - | - | - | $2,554,446 | 203 | $5,462,115 | Dec 21 | 01 Distribution | false |
| 15 | Lust, Caution | - | - | - | $2,178,546 | 160 | $2,396,632 | Jan 4 | BIM Distribuzione | false |
| 16 | Eastern Promises | - | - | - | $1,835,823 | 164 | $4,696,527 | Dec 14 | Eagle Pictures | false |
| 17 | Enchanted | - | - | - | $1,825,100 | 404 | $10,816,852 | Dec 7 | Walt Disney Pictures | false |
| 18 | The Secret of the Grain | - | - | - | $1,731,230 | 79 | $2,875,013 | Jan 11 | Lucky Red | false |
| 19 | Into the Wild | - | - | - | $1,715,606 | 191 | $8,058,998 | Jan 25 | BIM Distribuzione | false |
| 20 | The Bucket List | - | - | - | $1,473,141 | 243 | $2,820,300 | Jan 25 | Warner Bros. | false |
| 21 | Caramel | - | - | - | $1,238,613 | 50 | $2,301,033 | Dec 21 | Archibald | false |
| 22 | Irina Palm | - | - | - | $1,036,195 | 54 | $2,612,727 | Dec 7 | Teodora Film | false |
| 23 | Matrimonio alle Bahamas | - | - | - | $1,034,973 | 461 | $15,471,233 | Nov 16 | Medusa Distribuzione | false |
| 24 | Aliens vs. Predator: Requiem | - | - | - | $991,492 | 190 | $1,323,175 | Jan 25 | 20th Century Fox International | false |
| 25 | Mr. Magorium's Wonder Emporium | - | - | - | $765,687 | 160 | $2,466,591 | Jan 25 | Moviemax | false |
| 26 | Hui Buh: Das Schlossgespenst 2008 Re-release | - | - | - | $523,584 | 126 | $598,898 | Jan 4 | Moviemax | false |
| 27 | Signorina Effe | - | - | - | $389,755 | 71 | $524,476 | Jan 18 | 01 Distribution | false |
| 28 | In the Valley of Elah | - | - | - | $324,961 | 180 | $2,465,643 | Nov 30 | Mikado Film | false |
| 29 | The Return | - | - | - | $231,991 | 82 | $232,036 | Jan 18 | Eagle Pictures | false |
| 30 | Days of Darkness | - | - | - | $231,419 | 36 | $793,131 | Dec 7 | BIM Distribuzione | false |
| 31 | Ratatouille | - | - | - | $220,976 | 658 | $25,880,003 | Oct 19 | Walt Disney Pictures | false |
| 32 | Lars and the Real Girl | - | - | - | $214,969 | 30 | $224,211 | Jan 4 | - | false |
| 33 | Across the Universe | - | - | - | $201,140 | 77 | $1,227,260 | Nov 23 | Sony Pictures Releasing | false |
| 34 | Paranoid Park | - | - | - | $191,292 | 69 | $941,585 | Dec 7 | Lucky Red | false |
| 35 | The Assassination of Jesse James by the Coward Robert Ford | - | - | - | $190,689 | 83 | $577,583 | Dec 21 | Warner Bros. | false |
| 36 | Lezioni di cioccolato | - | - | - | $173,755 | 212 | $3,909,492 | Nov 23 | Universal Pictures International (UPI) | false |
| 37 | Winx Club: The Secret of the Lost Kingdom | - | - | - | $157,903 | 532 | $6,782,111 | Nov 30 | 01 Distribution | false |
| 38 | Days and Clouds | - | - | - | $133,961 | 214 | $6,010,383 | Oct 26 | Warner Bros. | false |
| 39 | Shelter Me | - | - | - | $102,714 | 10 | $144,691 | Jan 18 | - | false |
| 40 | The Savages | - | - | - | $98,497 | 27 | $498,767 | Jan 25 | 20th Century Fox International | false |
| 41 | I Could Never Be Your Woman | - | - | - | $86,706 | 20 | $142,461 | Jan 11 | - | false |
| 42 | Fracture | - | - | - | $77,163 | 192 | $3,521,113 | Nov 2 | Eagle Pictures | false |
| 43 | Hotel Meina | - | - | - | $68,985 | 28 | $116,536 | Jan 25 | Mikado Film | false |
| 44 | Don't Waste Your Time, Johnny! | - | - | - | $68,888 | 64 | $664,266 | Nov 30 | Medusa Distribuzione | false |
| 45 | Alien vs. Predator | - | - | - | $61,814 | 284 | $3,885,108 | Nov 19 | 20th Century Fox International | false |
| 46 | 1408 | - | - | - | $59,005 | 228 | $5,542,670 | Nov 23 | Lucky Red | false |
| 47 | Come tu mi vuoi | - | - | - | $46,783 | 367 | $10,947,653 | Nov 9 | Medusa Distribuzione | false |
| 48 | I Viceré | - | - | - | $46,599 | 187 | $2,584,556 | Nov 9 | 01 Distribution | false |
| 49 | The Wind Blows Round | - | - | - | $40,018 | 15 | $659,151 | May 4 | Aranciafilm | false |
| 50 | Bastardi II | - | - | - | $35,548 | 11 | $35,548 | Jan 4 | One Movie | false |
| 51 | Conversations with My Gardener | - | - | - | $23,337 | 30 | $422,659 | Nov 23 | BIM Distribuzione | false |
| 52 | The Jane Austen Book Club | - | - | - | $17,658 | 10 | $21,314 | Jan 18 | Sony Pictures Releasing | false |
| 53 | Little Boy Red | - | - | - | $17,167 | 6 | $227,801 | Nov 16 | - | false |
| 54 | August Rush | - | - | - | $15,145 | 190 | $1,462,687 | Nov 30 | Medusa Distribuzione | false |
| 55 | The Right Distance | - | - | - | $13,602 | 102 | $1,495,120 | Oct 19 | 01 Distribution | false |
| 56 | The Counterfeiters | - | - | - | $10,879 | 21 | $349,800 | Jan 25 | Lady Film | false |
| 57 | The Edge of Heaven | - | - | - | $10,787 | 47 | $674,318 | Nov 9 | BIM Distribuzione | false |
| 58 | Hitman | - | - | - | $9,471 | 224 | $1,977,980 | Dec 7 | 20th Century Fox International | false |
| 59 | Jellyfish | - | - | - | $9,290 | 13 | $226,959 | Nov 16 | Sacher Distribuzione | false |
| 60 | Welcome to the Roses 2007 Re-release | - | - | - | $6,316 | 16 | $375,465 | Oct 19 | Moviemax | false |
| 61 | Death at a Funeral | - | - | - | $6,239 | 218 | $3,318,228 | Sep 21 | Mikado Film | false |
| 62 | Surf's Up | - | - | - | $4,694 | 246 | $2,351,388 | Oct 5 | Sony Pictures Releasing | false |
| 63 | Tideland | - | - | - | $3,251 | 10 | $80,883 | Oct 31 | Officine UBU | false |
| 64 | Civico zero | - | - | - | $2,642 | 2 | $35,233 | Nov 23 | Istituto Luce | false |
| 65 | Factory Girl | - | - | - | $2,369 | 39 | $225,101 | Nov 23 | Moviemax | false |
| 66 | Youth Without Youth | - | - | - | $2,256 | 77 | $923,196 | Oct 26 | BIM Distribuzione | false |
| 67 | Red Like the Sky | - | - | - | $2,177 | 4 | $194,758 | Mar 30 | Lady Film | false |
| 68 | Bad Education | - | - | - | $1,382 | 230 | $5,381,033 | Oct 8 | Warner Bros. | false |
| 69 | Sophie Scholl: The Final Days | - | - | - | $1,294 | 54 | $1,034,241 | Oct 28 | Istituto Luce | false |
| 70 | Gli arcangeli | - | - | - | $1,255 | 1 | $1,255 | Jan 18 | - | false |
| 71 | Monsieur Batignole | - | - | - | $1,196 | 14 | $241,319 | Oct 4 | Lady Film | false |
| 72 | The Ugly Duckling and Me! | - | - | - | $1,189 | 50 | $155,737 | Jun 1 | Eagle Pictures | false |
| 73 | Piano, solo | - | - | - | $927 | 117 | $974,377 | Sep 21 | 01 Distribution | false |
| 74 | Catacombs | - | - | - | $839 | 93 | $515,970 | Jul 6 | Eagle Pictures | false |
| 75 | Dreamer | - | - | - | $818 | 128 | $197,933 | Sep 22 | Eagle Pictures | false |
| 76 | TMNT | - | - | - | $807 | 176 | $467,559 | Jun 22 | Warner Bros. | false |
| 77 | Music of the Heart 2001 Re-release | - | - | - | $789 | 3 | $77,013 | Apr 13 | - | false |
| 78 | 4 Months, 3 Weeks and 2 Days | - | - | - | $783 | 125 | $894,595 | Aug 24 | Lucky Red | false |
| 79 | A Mighty Heart | - | - | - | $753 | 14 | $49,722 | Nov 16 | Universal Pictures International (UPI) | false |
| 80 | The Nanny Diaries | - | - | - | $682 | 121 | $587,786 | Nov 30 | 01 Distribution | false |
| 81 | Atonement | - | - | - | $551 | 217 | $1,467,346 | Sep 21 | Universal Pictures International (UPI) | false |
| 82 | Reign Over Me | - | - | - | $508 | 11 | $20,357 | Aug 31 | Sony Pictures Releasing | false |
| 83 | Blood Diamond | - | - | - | $483 | 266 | $5,701,333 | Jan 26 | Warner Bros. | false |
| 84 | L'abbuffata | - | - | - | $391 | 88 | $220,414 | Nov 16 | Istituto Luce | false |
| 85 | Shrek the Third | - | - | - | $367 | 705 | $29,823,042 | Aug 31 | Universal Pictures International (UPI) | false |
| 86 | My Führer | - | - | - | $345 | 56 | $145,077 | Nov 23 | Warner Bros. | false |
