| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Night at the Museum | - | - | - | $12,867,904 | 708 | $20,409,103 | Dec 25 | 20th Century Fox International | false |
| 2 | Tired of Kissing Frogs | - | - | - | $4,441,115 | 350 | $6,633,548 | Dec 20 | Buena Vista International | false |
| 3 | Rocky Balboa | - | - | - | $4,022,725 | 278 | $4,885,033 | Jan 12 | 20th Century Fox International | false |
| 4 | Eragon | - | - | - | $3,833,776 | 700 | $10,643,431 | Dec 15 | 20th Century Fox International | false |
| 5 | Flushed Away | - | - | - | $2,416,681 | 600 | $6,616,758 | Dec 15 | United International Pictures | false |
| 6 | Apocalypto | - | - | - | $2,365,480 | 371 | $8,012,656 | Jan 26 | 20th Century Fox International | false |
| 7 | The Holiday | - | - | - | $2,263,311 | 250 | $3,444,255 | Jan 12 | Universal Pictures International (UPI) | false |
| 8 | Perfume: The Story of a Murderer | - | - | - | $2,191,956 | 201 | $4,929,972 | Jan 19 | Gussi Films | false |
| 9 | Fuera del cielo | - | - | - | $2,109,429 | 158 | $3,086,315 | Jan 12 | Videocine | false |
| 10 | Charlotte's Web | - | - | - | $2,018,071 | 350 | $2,333,538 | Dec 29 | United International Pictures | false |
| 11 | Casino Royale | - | - | - | $1,668,946 | 564 | $6,557,256 | Dec 8 | Sony Pictures Releasing | false |
| 12 | Happy Feet | - | - | - | $1,295,471 | 606 | $6,252,783 | Dec 8 | Warner Bros. | false |
| 13 | Unaccompanied Minors | - | - | - | $944,885 | 204 | $1,488,851 | Dec 25 | Warner Bros. | false |
| 14 | Material Girls | - | - | - | $860,708 | 176 | $1,628,878 | Dec 15 | Videocine | false |
| 15 | Stormbreaker | - | - | - | $706,612 | 150 | $1,010,381 | Jan 5 | Azteca Films | false |
| 16 | Borat | - | - | - | $610,440 | 60 | $1,035,175 | Jan 5 | 20th Century Fox International | false |
| 17 | The Wicker Man | - | - | - | $592,265 | 74 | $1,342,206 | Nov 10 | Gussi Films | false |
| 18 | Saint Ange 2006 Re-release | - | - | - | $555,830 | 69 | $1,012,236 | Dec 29 | Gussi Films | false |
| 19 | Pulse | - | - | - | $486,121 | 75 | $1,229,012 | Oct 20 | Gussi Films | false |
| 20 | Lucky Number Slevin | - | - | - | $363,361 | 76 | $1,127,224 | Oct 27 | Gussi Films | false |
| 21 | Babel | - | - | - | $248,513 | 300 | $7,349,426 | Nov 10 | United International Pictures | false |
| 22 | Gridiron Gang | - | - | - | $224,173 | 180 | $878,199 | Dec 1 | Sony Pictures Releasing | false |
| 23 | Dreamgirls | - | - | - | $220,114 | 120 | $713,712 | Jan 26 | Paramount Pictures International | false |
| 24 | The Long Weekend | - | - | - | $190,527 | 100 | $517,898 | Jan 19 | Videocine | false |
| 25 | Flags of Our Fathers | - | - | - | $106,184 | 89 | $563,544 | Jan 26 | Warner Bros. | false |
| 26 | A Good Year | - | - | - | $105,323 | 200 | $1,034,183 | Dec 1 | 20th Century Fox International | false |
| 27 | The Texas Chainsaw Massacre: The Beginning | - | - | - | $100,241 | 125 | $570,597 | Jan 26 | Gussi Films | false |
| 28 | Scoop | - | - | - | $96,832 | 21 | $284,068 | Jan 19 | Gussi Films | false |
| 29 | The Science of Sleep | - | - | - | $81,170 | 125 | $407,465 | Nov 17 | Tarantula Films | false |
| 30 | Crank | - | - | - | $79,380 | 55 | $456,879 | Jan 5 | Gussi Films | false |
| 31 | Tsotsi | - | - | - | $57,052 | 40 | $231,588 | Jan 5 | Videocine | false |
| 32 | Stranger Than Fiction | - | - | - | $56,453 | 25 | $268,209 | Jan 12 | Sony Pictures Releasing | false |
| 33 | Invincible | - | - | - | $42,690 | 50 | $377,784 | Nov 10 | Gussi Films | false |
| 34 | A Sound of Thunder | - | - | - | $35,149 | 45 | $953,667 | Oct 6 | Gussi Films | false |
| 35 | Breaking and Entering | - | - | - | $32,951 | 15 | $172,806 | Jan 5 | Buena Vista International | false |
| 36 | Children of Men | - | - | - | $22,487 | 258 | $2,505,554 | Nov 24 | United International Pictures | false |
| 37 | Deja Vu | - | - | - | $21,242 | 400 | $4,168,156 | Nov 24 | Buena Vista International | false |
| 38 | Deck the Halls | - | - | - | $15,893 | 250 | $1,169,660 | Dec 8 | 20th Century Fox International | false |
| 39 | The Santa Clause 3: The Escape Clause | - | - | - | $15,870 | 310 | $2,455,059 | Dec 1 | Buena Vista International | false |
| 40 | On the Edge | - | - | - | $15,595 | 300 | $2,119,800 | Nov 24 | Videocine | false |
| 41 | Pan's Labyrinth | - | - | - | $12,235 | 190 | $6,883,588 | Oct 20 | Warner Bros. | false |
| 42 | The Nightmare Before Christmas 2006 3D Release | - | - | - | $4,150 | 5 | $415,951 | Nov 17 | Buena Vista International | false |
