| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Yogi Bear | - | - | - | $9,889,870 | 878 | $10,456,252 | Feb 4 | Warner Bros. | false |
| 2 | The Rite | - | - | - | $6,423,043 | 554 | $11,365,781 | Feb 18 | Warner Bros. | false |
| 3 | Black Swan | - | - | - | $5,973,454 | 305 | $9,645,726 | Feb 11 | 20th Century Fox International | false |
| 4 | Just Go with It | - | - | - | $5,780,352 | 501 | $7,541,885 | Feb 11 | Sony Pictures Releasing | false |
| 5 | Season of the Witch | - | - | - | $3,465,460 | 359 | $5,039,134 | Jan 28 | Gussi Films | false |
| 6 | Julia's Eyes | - | - | - | $3,122,052 | 388 | $3,268,234 | Feb 4 | Universal Pictures International (UPI) | false |
| 7 | The Green Hornet | - | - | - | $2,644,895 | 708 | $7,895,269 | Jan 21 | Sony Pictures Releasing | false |
| 8 | Presumed Guilty | - | - | - | $1,547,442 | 307 | $6,585,640 | Feb 18 | - | false |
| 9 | The Tourist | - | - | - | $1,406,391 | 350 | $5,576,546 | Jan 14 | Sony Pictures Releasing | false |
| 10 | True Grit | - | - | - | $1,159,193 | 155 | $1,402,472 | Feb 4 | Paramount Pictures International | false |
| 11 | Big Mommas: Like Father, Like Son | - | - | - | $1,139,259 | 450 | $3,761,284 | Feb 25 | 20th Century Fox International | false |
| 12 | The King's Speech | - | - | - | $1,056,017 | 178 | $4,145,244 | Feb 18 | Videocine | false |
| 13 | Love & Other Drugs | - | - | - | $999,344 | 250 | $2,380,041 | Jan 21 | 20th Century Fox International | false |
| 14 | The Fighter | - | - | - | $839,649 | 155 | $1,324,973 | Feb 11 | Gussi Films | false |
| 15 | Sanctum | - | - | - | $769,278 | 585 | $1,948,096 | Feb 25 | - | false |
| 16 | Burlesque | - | - | - | $750,469 | 200 | $1,155,918 | Jan 28 | Sony Pictures Releasing | false |
| 17 | No Strings Attached | - | - | - | $723,929 | 300 | $4,986,344 | Feb 25 | Paramount Pictures International | false |
| 18 | Hereafter | - | - | - | $537,178 | 200 | $2,644,498 | Jan 7 | Warner Bros. | false |
| 19 | Megamind | - | - | - | $510,621 | 865 | $14,231,674 | Dec 16 | Paramount Pictures International | false |
| 20 | Tron: Legacy | - | - | - | $460,891 | 990 | $14,298,825 | Dec 25 | Walt Disney Pictures | false |
| 21 | Let Me In | - | - | - | $443,256 | 250 | $1,316,517 | Jan 21 | Paramount Pictures International | false |
| 22 | Gulliver's Travels | - | - | - | $396,402 | 1,016 | $11,595,299 | Dec 23 | 20th Century Fox International | false |
| 23 | Splice 2010 Re-release | - | - | - | $388,245 | 173 | $1,052,060 | Jan 14 | Videocine | false |
| 24 | The Chronicles of Narnia: The Voyage of the Dawn Treader | - | - | - | $375,899 | 1,209 | $16,749,459 | Dec 10 | 20th Century Fox International | false |
| 25 | Stone | - | - | - | $322,429 | 115 | $655,036 | Jan 28 | - | false |
| 26 | Sin memoria | - | - | - | $289,566 | 150 | $322,748 | Feb 11 | Videocine | false |
| 27 | Unstoppable | - | - | - | $282,788 | 500 | $3,956,996 | Jan 7 | 20th Century Fox International | false |
| 28 | Little Fockers | - | - | - | $271,802 | 550 | $7,274,874 | Dec 30 | Paramount Pictures International | false |
| 29 | The Next Three Days | - | - | - | $231,516 | 269 | $1,951,942 | Dec 30 | Gussi Films | false |
| 30 | 127 Hours | - | - | - | $216,591 | 100 | $1,143,116 | Feb 25 | 20th Century Fox International | false |
| 31 | Serious Moonlight | - | - | - | $173,757 | 99 | $209,631 | Feb 4 | - | false |
| 32 | The Social Network | - | - | - | $169,554 | 250 | $3,239,209 | Dec 10 | Sony Pictures Releasing | false |
| 33 | The Concert | - | - | - | $142,253 | 19 | $293,111 | Jan 14 | - | false |
| 34 | My Soul to Take | - | - | - | $95,292 | 51 | $241,534 | Jan 14 | Gussi Films | false |
| 35 | You Will Meet a Tall Dark Stranger | - | - | - | $81,773 | 50 | $345,759 | Jan 14 | - | false |
| 36 | Hot Tub Time Machine | - | - | - | $74,433 | 100 | $255,621 | Feb 18 | - | false |
| 37 | High Lane | - | - | - | $69,602 | 67 | $178,186 | Jan 21 | - | false |
| 38 | This Is Not a Movie | - | - | - | $57,764 | 61 | $116,801 | Jan 28 | Videocine | false |
| 39 | Faster | - | - | - | $43,025 | 80 | $421,869 | Feb 25 | Sony Pictures Releasing | false |
| 40 | Dog Pound | - | - | - | $35,684 | 40 | $35,684 | Feb 11 | - | false |
| 41 | I Am Number Four | - | - | - | $28,558 | 406 | $2,034,825 | Mar 4 | Walt Disney Pictures | false |
| 42 | Somewhere | - | - | - | $22,217 | 20 | $84,728 | Jan 14 | Universal Pictures International (UPI) | false |
| 43 | Marcelino Pan y Vino | - | - | - | $17,509 | 230 | $494,122 | Dec 16 | - | false |
| 44 | The Killer Inside Me | - | - | - | $16,986 | 49 | $212,649 | Dec 16 | - | false |
| 45 | Baaria | - | - | - | $16,291 | 33 | $127,872 | Dec 30 | Videocine | false |
| 46 | Anything for Her | - | - | - | $14,579 | 12 | $25,316 | Jan 28 | - | false |
| 47 | Fish Tank | - | - | - | $12,132 | 9 | $22,261 | Jan 28 | - | false |
| 48 | The Goods: Live Hard, Sell Hard | - | - | - | $10,649 | 41 | $10,649 | Feb 11 | - | false |
| 49 | The White Ribbon | - | - | - | $8,770 | 7 | $83,884 | Dec 23 | - | false |
| 50 | To Save a Life | - | - | - | $7,119 | 30 | $38,221 | Jan 14 | - | false |
| 51 | Buddha Collapsed Out of Shame 2010 Re-release | - | - | - | $6,159 | 10 | $6,159 | Feb 11 | - | false |
| 52 | The Other Guys | - | - | - | $5,206 | 100 | $840,985 | Oct 22 | Sony Pictures Releasing | false |
| 53 | Machete | - | - | - | $4,647 | 200 | $945,321 | Nov 12 | Sony Pictures Releasing | false |
| 54 | Bright Star | - | - | - | $4,037 | 17 | $40,812 | Jan 21 | Gussi Films | false |
