| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Avatar | - | - | - | $2,854,738 | 196 | $15,866,546 | Dec 16 | 20th Century Fox International | false |
| 2 | The Princess and the Frog | - | - | - | $2,833,888 | 81 | $3,235,435 | Feb 3 | Walt Disney Pictures | false |
| 3 | Percy Jackson & the Olympians: The Lightning Thief | - | - | - | $1,738,422 | 80 | $2,090,477 | Feb 10 | 20th Century Fox International | false |
| 4 | Valentine's Day | - | - | - | $1,316,644 | 48 | $1,583,712 | Feb 10 | 20th Century Fox International | false |
| 5 | Bo | - | - | - | $1,014,832 | 23 | $1,524,017 | Feb 10 | Kinepolis Film Distribution (KFD) | false |
| 6 | The Wolfman | - | - | - | $970,626 | 36 | $1,104,657 | Feb 10 | Universal Pictures International (UPI) | false |
| 7 | Shutter Island | - | - | - | $745,373 | 46 | $3,000,673 | Feb 24 | Universal Pictures International (UPI) | false |
| 8 | Planet 51 | - | - | - | $665,521 | 61 | $862,786 | Feb 10 | Belga Films | false |
| 9 | Sherlock Holmes | - | - | - | $653,586 | 75 | $2,763,022 | Jan 6 | Warner Bros. | false |
| 10 | Alvin and the Chipmunks: The Squeakquel | - | - | - | $566,923 | 93 | $4,461,871 | Dec 23 | 20th Century Fox International | false |
| 11 | The Book of Eli | - | - | - | $554,954 | 32 | $574,030 | Feb 3 | Paradiso Entertainment | false |
| 12 | Oceans | - | - | - | $481,808 | 26 | $732,605 | Jan 27 | Alternative Films | false |
| 13 | Up in the Air | - | - | - | $472,965 | 26 | $1,113,452 | Jan 20 | Universal Pictures International (UPI) | false |
| 14 | Edge of Darkness | - | - | - | $450,274 | 44 | $716,475 | Feb 17 | Kinepolis Film Distribution (KFD) | false |
| 15 | Cloudy with a Chance of Meatballs | - | - | - | $435,223 | 42 | $1,122,314 | Jan 13 | Sony Pictures Releasing | false |
| 16 | The Pimp | - | - | - | $433,790 | 18 | $817,722 | Feb 17 | Belga Films | false |
| 17 | The Lovely Bones | - | - | - | $399,576 | 33 | $498,758 | Feb 10 | Universal Pictures International (UPI) | false |
| 18 | Gainsbourg: A Heroic Life | - | - | - | $395,373 | 21 | $462,434 | Feb 3 | Cinéart | false |
| 19 | Did You Hear About the Morgans? | - | - | - | $368,526 | 27 | $756,459 | Jan 27 | Sony Pictures Releasing | false |
| 20 | Dossier K. | - | - | - | $291,567 | 38 | $3,647,079 | Dec 9 | Kinepolis Film Distribution (KFD) | false |
| 21 | I Love You Phillip Morris | - | - | - | $258,853 | 27 | $393,388 | Feb 17 | Belga Films | false |
| 22 | The Imaginarium of Doctor Parnassus | - | - | - | $242,446 | 16 | $371,963 | Feb 10 | Kinepolis Film Distribution (KFD) | false |
| 23 | A Serious Man | - | - | - | $220,720 | 13 | $489,273 | Jan 20 | Universal Pictures International (UPI) | false |
| 24 | Invictus | - | - | - | $208,071 | 25 | $738,223 | Jan 13 | Warner Bros. | false |
| 25 | Mr. Nobody | - | - | - | $193,685 | 36 | $816,771 | Jan 13 | Belga Films | false |
| 26 | The Road | - | - | - | $191,784 | 24 | $367,861 | Jan 27 | Benelux Film Distributors | false |
| 27 | From Paris with Love | - | - | - | $153,114 | 33 | $452,140 | Feb 24 | Belga Films | false |
| 28 | Protéger & servir | - | - | - | $101,915 | 9 | $101,915 | Feb 3 | Alternative Films | false |
| 29 | A Single Man | - | - | - | $87,356 | 12 | $397,654 | Feb 24 | Cinéart | false |
| 30 | OceanWorld | - | - | - | $70,623 | 15 | $71,727 | Feb 10 | - | false |
| 31 | Vincere | - | - | - | $70,099 | 8 | $82,225 | Feb 10 | ABC Distribution | false |
| 32 | Plop en de kabouterbaby | - | - | - | $64,918 | 34 | $1,540,037 | Dec 9 | Kinepolis Film Distribution (KFD) | false |
| 33 | It's Complicated | - | - | - | $60,504 | 43 | $1,459,580 | Dec 23 | Universal Pictures International (UPI) | false |
| 34 | Fantastic Mr. Fox | - | - | - | $57,472 | 17 | $78,578 | Feb 17 | 20th Century Fox International | false |
| 35 | Brothers | - | - | - | $44,061 | 19 | $313,467 | Dec 23 | A-Film Distribution | false |
| 36 | Anubis en de wraak van Arghus | - | - | - | $44,052 | 30 | $1,053,397 | Dec 16 | Kinepolis Film Distribution (KFD) | false |
| 37 | The Men Who Stare at Goats | - | - | - | $42,523 | 14 | $327,273 | Jan 6 | Kinepolis Film Distribution (KFD) | false |
| 38 | The Girl Who Played with Fire | - | - | - | $41,830 | 21 | $196,087 | Jan 13 | Benelux Film Distributors | false |
| 39 | No One Knows About Persian Cats | - | - | - | $36,237 | 6 | $56,739 | Jan 27 | Cinéart | false |
| 40 | The Concert | - | - | - | $31,054 | 15 | $820,323 | Nov 11 | Cinéart | false |
| 41 | Bright Star | - | - | - | $30,191 | 7 | $133,313 | Dec 9 | Paradiso Entertainment | false |
| 42 | Capitalism: A Love Story | - | - | - | $29,962 | 16 | $162,408 | Jan 6 | Paradiso Entertainment | false |
| 43 | An Education | - | - | - | $29,712 | 8 | $107,283 | Feb 24 | Kinepolis Film Distribution (KFD) | false |
| 44 | Horse | - | - | - | $26,676 | 5 | $26,676 | Feb 10 | Cinéart | false |
| 45 | Angel at Sea | - | - | - | $20,753 | 3 | $22,069 | Feb 10 | - | false |
| 46 | Altiplano | - | - | - | $18,834 | 6 | $154,835 | Nov 25 | - | false |
| 47 | Silent Voice | - | - | - | $14,813 | 4 | $21,147 | Feb 17 | Cinéart | false |
| 48 | The Ordinary People | - | - | - | $12,794 | 5 | $29,091 | Jan 20 | Cinéart | false |
| 49 | The Boat Race | - | - | - | $12,791 | 6 | $37,657 | Feb 24 | Cinéart | false |
| 50 | The Barons | - | - | - | $9,371 | 13 | $1,266,035 | Nov 4 | Cinéart | false |
| 51 | Paranormal Activity | - | - | - | $7,053 | 20 | $1,155,278 | Nov 25 | Kinepolis Film Distribution (KFD) | false |
| 52 | Coco Chanel & Igor Stravinsky | - | - | - | $5,914 | 8 | $77,413 | Jan 6 | Cinéart | false |
| 53 | 2012 | - | - | - | $4,956 | 98 | $6,322,004 | Nov 11 | Sony Pictures Releasing | false |
| 54 | 4, 5, 6... Mélie pain d'épice | - | - | - | $4,521 | 2 | $5,545 | Feb 17 | - | false |
| 55 | Mary and Max | - | - | - | $4,253 | 3 | $18,078 | Feb 24 | Kinepolis Film Distribution (KFD) | false |
| 56 | Hadewijch | - | - | - | $3,247 | 5 | $3,788 | Feb 24 | - | false |
| 57 | Creation | - | - | - | $1,394 | 5 | $22,281 | Jan 20 | A-Film Distribution | false |
| 58 | The Whistler | - | - | - | $1,216 | 13 | $211,103 | Jan 6 | Benelux Film Distributors | false |
| 59 | Jasper: Journey to the End of the World | - | - | - | $1,159 | 6 | $1,159 | Feb 10 | - | false |
| 60 | Eastern Plays | - | - | - | $1,102 | 2 | $1,858 | Feb 24 | - | false |
| 61 | Katalin Varga | - | - | - | $960 | 1 | $2,461 | Feb 24 | Benelux Film Distributors | false |
| 62 | Pettson & Findus - Katten och gubbens år 2009 Re-release | - | - | - | $297 | 3 | $1,177 | Feb 10 | Jekino | false |
