| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | The Curious Case of Benjamin Button | - | - | - | $1,752,534 | - | $2,328,845 | Feb 13 | Warner Bros. | false |
| 2 | Yes Man | - | - | - | $1,389,054 | - | $2,942,790 | Jan 23 | Warner Bros. | false |
| 3 | He's Just Not That Into You | - | - | - | $986,088 | - | $1,282,755 | Feb 13 | ARM Distribution | false |
| 4 | Red Cliff II | - | - | - | $602,749 | - | $4,512,737 | Jan 15 | 20th Century Fox International | false |
| 5 | Valkyrie | - | - | - | $588,891 | - | $695,875 | Feb 13 | 20th Century Fox International | false |
| 6 | Bride Wars | - | - | - | $526,223 | - | $1,186,291 | Jan 24 | 20th Century Fox International | false |
| 7 | Inkheart | - | - | - | $525,709 | - | $1,815,500 | Jan 23 | ARM Distribution | false |
| 8 | Marley & Me | - | - | - | $520,172 | - | $773,889 | Feb 21 | 20th Century Fox International | false |
| 9 | Seven Pounds | - | - | - | $469,998 | - | $514,496 | Feb 7 | Walt Disney Studios Sony Pictures Releasing (WDSSPR) | false |
| 10 | Madagascar: Escape 2 Africa | - | - | - | $321,820 | - | $1,529,524 | Jan 24 | United International Pictures | false |
| 11 | Revolutionary Road | - | - | - | $309,598 | - | $312,845 | Feb 6 | United International Pictures | false |
| 12 | Coming Soon | - | - | - | $276,679 | - | $613,175 | Feb 20 | - | false |
| 13 | Ponyo | - | - | - | $241,152 | - | $1,072,756 | Jan 23 | Walt Disney Studios Sony Pictures Releasing (WDSSPR) | false |
| 14 | The International | - | - | - | $130,209 | - | $256,377 | Feb 20 | Walt Disney Studios Sony Pictures Releasing (WDSSPR) | false |
| 15 | Confessions of a Shopaholic | - | - | - | $122,250 | - | $828,714 | Feb 27 | Walt Disney Studios Sony Pictures Releasing (WDSSPR) | false |
| 16 | Detroit Metal City | - | - | - | $90,776 | - | $403,564 | Jan 16 | - | false |
| 17 | Naruto Shippuden: The Movie - Bonds | - | - | - | $89,527 | - | $226,585 | Jan 30 | - | false |
| 18 | Milk | - | - | - | $45,523 | - | $139,288 | Feb 20 | - | false |
| 19 | Frost/Nixon | - | - | - | $17,404 | - | $19,188 | Feb 13 | United International Pictures | false |
| 20 | Rabbit Without Ears | - | - | - | $14,327 | - | $42,204 | Jan 23 | - | false |
| 21 | The Wrestler | - | - | - | $14,205 | - | $21,343 | Feb 20 | - | false |
| 22 | Doubt | - | - | - | $13,159 | - | $19,261 | Feb 20 | Walt Disney Studios Sony Pictures Releasing (WDSSPR) | false |
| 23 | 100 Feet | - | - | - | $9,571 | - | $11,801 | Feb 6 | Long Shong Entertainment Multimedia Company | false |
| 24 | The Class | - | - | - | $9,304 | - | $16,916 | Feb 20 | - | false |
| 25 | Elsa & Fred | - | - | - | $8,133 | - | $9,509 | Feb 13 | - | false |
| 26 | Flashbacks of a Fool | - | - | - | $6,189 | - | $21,640 | Jan 30 | - | false |
| 27 | Man on Wire | - | - | - | $5,393 | - | $5,956 | Feb 6 | - | false |
| 28 | Storm Rider Clash of the Evils | - | - | - | $2,406 | - | $2,768 | Feb 13 | - | false |
