| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Jumper | - | - | - | $747,366 | 65 | $1,722,746 | Feb 13 | - | false |
| 2 | Vantage Point | - | - | - | $394,319 | 50 | $723,747 | Feb 20 | - | false |
| 3 | Cloverfield | - | - | - | $378,174 | 35 | $413,374 | Jan 30 | - | false |
| 4 | Aliens vs. Predator: Requiem | - | - | - | $375,424 | 55 | $902,056 | Jan 23 | - | false |
| 5 | Rambo | - | - | - | $372,188 | 45 | $707,685 | Jan 23 | - | false |
| 6 | 27 Dresses | - | - | - | $360,997 | 28 | $437,273 | Jan 30 | - | false |
| 7 | The Eye | - | - | - | $260,384 | 30 | $260,384 | Feb 6 | - | false |
| 8 | The Spiderwick Chronicles | - | - | - | $216,202 | 32 | $610,706 | Feb 14 | - | false |
| 9 | In the Name of the King: A Dungeon Siege Tale | - | - | - | $201,364 | 20 | $212,027 | Jan 30 | - | false |
| 10 | Alvin and the Chipmunks | - | - | - | $200,005 | 35 | $636,128 | Jan 16 | - | false |
| 11 | One Missed Call | - | - | - | $177,978 | 25 | $256,965 | Jan 30 | - | false |
| 12 | National Treasure: Book of Secrets | - | - | - | $158,610 | 90 | $2,354,779 | Jan 8 | - | false |
| 13 | The Mist | - | - | - | $141,352 | 20 | $176,424 | Feb 6 | - | false |
| 14 | Saw IV | - | - | - | $140,112 | 20 | $140,112 | Jan 30 | - | false |
| 15 | The Bucket List | - | - | - | $120,614 | 20 | $120,614 | Feb 6 | - | false |
| 16 | Good Luck Chuck | - | - | - | $108,029 | 43 | $121,603 | Feb 6 | - | false |
| 17 | I Am Legend | - | - | - | $88,263 | 62 | $1,509,056 | Jan 8 | - | false |
| 18 | Dragon Wars: D-War | - | - | - | $68,568 | 20 | $357,099 | Jan 16 | - | false |
| 19 | American Gangster | - | - | - | $61,756 | 25 | $151,381 | Jan 23 | - | false |
| 20 | Untraceable | - | - | - | $59,516 | 18 | $119,676 | Feb 20 | - | false |
| 21 | Juno | - | - | - | $52,333 | 16 | $82,296 | Feb 13 | - | false |
| 22 | The Assassination of Jesse James by the Coward Robert Ford | - | - | - | $38,718 | 13 | $41,240 | Feb 20 | - | false |
| 23 | P.S. I Love You | - | - | - | $35,710 | 16 | $98,202 | Jan 23 | - | false |
| 24 | Sweeney Todd: The Demon Barber of Fleet Street | - | - | - | $30,784 | 20 | $230,499 | Jan 16 | - | false |
| 25 | P2 | - | - | - | $24,983 | 16 | $25,662 | Feb 20 | - | false |
| 26 | The Heartbreak Kid | - | - | - | $23,152 | 25 | $177,707 | Jan 16 | - | false |
| 27 | Blonde Ambition | - | - | - | $12,606 | 10 | $16,538 | Feb 20 | - | false |
| 28 | The Darjeeling Limited | - | - | - | $10,086 | 1 | $10,086 | Feb 6 | - | false |
| 29 | Bee Movie | - | - | - | $4,073 | 45 | $322,840 | Jan 8 | - | false |
| 30 | There Will Be Blood | - | - | - | $3,354 | 1 | $8,331 | Feb 13 | - | false |
| 31 | The Kingdom | - | - | - | $129 | 30 | $432,829 | Nov 28 | - | false |
