| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | KM 31: Kilometre 31 | - | - | - | $7,388,868 | 275 | $10,963,219 | Feb 2 | Videocine | false |
| 2 | The Pursuit of Happyness | - | - | - | $5,591,219 | 303 | $7,789,998 | Feb 2 | Sony Pictures Releasing | false |
| 3 | Ghost Rider | - | - | - | $4,185,938 | 354 | $7,324,746 | Feb 16 | Sony Pictures Releasing | false |
| 4 | Apocalypto | - | - | - | $3,902,740 | 371 | $8,012,656 | Jan 26 | 20th Century Fox International | false |
| 5 | Blood Diamond | - | - | - | $3,092,272 | 350 | $4,112,166 | Feb 9 | Warner Bros. | false |
| 6 | Perfume: The Story of a Murderer | - | - | - | $1,646,231 | 201 | $4,929,972 | Jan 19 | Gussi Films | false |
| 7 | Night at the Museum | - | - | - | $1,280,215 | 708 | $20,409,103 | Dec 25 | 20th Century Fox International | false |
| 8 | Norbit | - | - | - | $1,246,087 | 350 | $4,894,096 | Feb 23 | Paramount Pictures International | false |
| 9 | Pan's Labyrinth | - | - | - | $1,076,612 | 190 | $6,883,588 | Oct 20 | Warner Bros. | false |
| 10 | The Holiday | - | - | - | $782,255 | 250 | $3,444,255 | Jan 12 | Universal Pictures International (UPI) | false |
| 11 | Fuera del cielo | - | - | - | $618,174 | 158 | $3,086,315 | Jan 12 | Videocine | false |
| 12 | Rocky Balboa | - | - | - | $557,762 | 278 | $4,885,033 | Jan 12 | 20th Century Fox International | false |
| 13 | Employee of the Month | - | - | - | $420,024 | 148 | $713,060 | Feb 9 | Videocine | false |
| 14 | Never on a Sunday | - | - | - | $341,379 | 200 | $513,004 | Feb 16 | Gussi Films | false |
| 15 | Babel | - | - | - | $323,443 | 300 | $7,349,426 | Nov 10 | United International Pictures | false |
| 16 | Dreamgirls | - | - | - | $279,226 | 120 | $713,712 | Jan 26 | Paramount Pictures International | false |
| 17 | The Wicker Man | - | - | - | $255,778 | 74 | $1,342,206 | Nov 10 | Gussi Films | false |
| 18 | Saint Ange 2006 Re-release | - | - | - | $250,105 | 69 | $1,012,236 | Dec 29 | Gussi Films | false |
| 19 | Tired of Kissing Frogs | - | - | - | $245,877 | 350 | $6,633,548 | Dec 20 | Buena Vista International | false |
| 20 | How Much Do You Love Me? | - | - | - | $243,452 | 103 | $456,742 | Feb 16 | Azteca Films | false |
| 21 | The Long Weekend | - | - | - | $182,321 | 100 | $517,898 | Jan 19 | Videocine | false |
| 22 | Notes on a Scandal | - | - | - | $159,737 | 80 | $1,013,500 | Feb 23 | 20th Century Fox International | false |
| 23 | Unaccompanied Minors | - | - | - | $157,015 | 204 | $1,488,851 | Dec 25 | Warner Bros. | false |
| 24 | Stormbreaker | - | - | - | $139,531 | 150 | $1,010,381 | Jan 5 | Azteca Films | false |
| 25 | The Texas Chainsaw Massacre: The Beginning | - | - | - | $134,349 | 125 | $570,597 | Jan 26 | Gussi Films | false |
| 26 | Little Children | - | - | - | $81,149 | 60 | $464,044 | Feb 23 | Gussi Films | false |
| 27 | Flags of Our Fathers | - | - | - | $59,889 | 89 | $563,544 | Jan 26 | Warner Bros. | false |
| 28 | Flushed Away | - | - | - | $58,841 | 600 | $6,616,758 | Dec 15 | United International Pictures | false |
| 29 | Letters from Iwo Jima | - | - | - | $57,710 | 50 | $271,521 | Feb 16 | Warner Bros. | false |
| 30 | The Last King of Scotland | - | - | - | $57,365 | 18 | $662,365 | Feb 9 | 20th Century Fox International | false |
| 31 | Children of Men | - | - | - | $56,497 | 258 | $2,505,554 | Nov 24 | United International Pictures | false |
| 32 | Charlotte's Web | - | - | - | $53,110 | 350 | $2,333,538 | Dec 29 | United International Pictures | false |
| 33 | Eragon | - | - | - | $46,060 | 700 | $10,643,431 | Dec 15 | 20th Century Fox International | false |
| 34 | Borat | - | - | - | $44,065 | 60 | $1,035,175 | Jan 5 | 20th Century Fox International | false |
