Domestic Box Office For December 2021
Key:Estimated
| Rank | Release | Gross | Max Th | Opening | % of Total | Open Th | Open | Close | Distributor |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Spider-Man: No Way Home | $804,793,477 | 4,336 | $260,138,569 | 32.3% | 4,336 | Dec 17 | Jun 30 | Sony Pictures Releasing |
| 2 | Sing 2 | $162,790,990 | 3,892 | $22,326,230 | 13.7% | 3,892 | Dec 22 | - | Universal Pictures |
| 3 | West Side Story | $38,530,322 | 2,820 | $10,574,618 | 27.4% | 2,820 | Dec 10 | Apr 7 | 20th Century Studios |
| 4 | The Matrix Resurrections | $37,686,805 | 3,552 | $10,749,011 | 28.5% | 3,552 | Dec 22 | - | Warner Bros. |
| 5 | The King's Man | $37,176,373 | 3,180 | $5,915,542 | 15.9% | 3,180 | Dec 22 | Mar 10 | 20th Century Studios |
| 6 | American Underdog | $26,514,814 | 2,813 | $5,861,836 | 22.1% | 2,813 | Dec 25 | - | Lionsgate |
| 7 | Christmas with the Chosen: The Messengers | $13,728,000 | 1,700 | $4,245,000 | 30.9% | 1,700 | Dec 1 | - | Fathom Events |
| 8 | Nightmare Alley | $11,338,107 | 2,145 | $2,811,703 | 24.8% | 2,145 | Dec 17 | - | Searchlight Pictures |
| 9 | A Journal for Jordan | $6,545,174 | 2,500 | $2,201,886 | 33.6% | 2,500 | Dec 25 | - | Sony Pictures Releasing |
| 10 | '83 | $4,055,660 | 486 | $1,692,575 | 41.7% | 486 | Dec 23 | - | Reliance Entertainment |
| 11 | Parallel Mothers | $2,297,501 | 684 | $38,249 | 1.7% | 3 | Dec 24 | - | Sony Pictures Classics |
| 12 | Pushpa: The Rise - Part 1 | $1,320,000 | 400 | $1,320,000 | - | 400 | Dec 17 | - | Hamsini Entertainment |
| 13 | Sword Art Online: Progressive - Aria of a Starless Night | $1,050,000 | 840 | $1,050,000 | - | 840 | Dec 3 | - | FUNimation Entertainment |
| 14 | True to the Game 3 | $1,038,255 | 440 | $573,031 | 55.2% | 440 | Dec 3 | - | Faith Media Distribution |
| 15 | Red Rocket | $1,023,086 | 385 | $88,195 | 8.6% | 6 | Dec 10 | - | A24 |
| 16 | The Matrix 2021 Re-release | $596,998 | - | - | - | - | Dec 6 | - | Warner Bros. |
| 17 | National Champions | $475,488 | 1,197 | $301,028 | 63.3% | 1,197 | Dec 10 | - | STX Entertainment |
| 18 | Benedetta | $354,481 | 201 | $136,839 | 38.6% | 201 | Dec 3 | - | IFC Films |
| 19 | Flee | $339,754 | 220 | $24,794 | 7.3% | 4 | Dec 3 | - | Neon |
| 20 | The Lady of Heaven | $291,597 | 59 | - | - | - | Dec 10 | - | Universal Pictures International (UPI) |
| 21 | The Witches | $203,571 | - | - | - | - | Dec 25 | - | Warner Bros. |
| 22 | The Velvet Queen | $151,006 | 51 | $4,276 | - | 2 | Dec 22 | - | Oscilloscope |
| 23 | Wolf | $147,595 | 308 | $82,640 | 56% | 308 | Dec 3 | - | Focus Features |
| 24 | Tadap | $130,934 | 63 | $56,570 | 43.2% | 63 | Dec 3 | - | FIP |
| 25 | Jockey | $108,678 | 64 | $2,789 | 2.6% | 3 | Dec 29 | - | Sony Pictures Classics |
| 26 | Torn | $52,816 | 22 | - | - | - | Dec 3 | - | Dada Films |
| 27 | Memoria | $52,656 | 1 | $6,797 | 12.9% | 1 | Dec 26 | - | Neon |
| 28 | France | $49,347 | 12 | $5,811 | 11.8% | 2 | Dec 10 | Feb 10 | Kino Lorber |
| 29 | The Scary of Sixty-First | $45,005 | 9 | $7,808 | 17.3% | 1 | Dec 3 | - | Utopia |
| 30 | Schemes in Antiques | $36,501 | 28 | $36,501 | 100% | 28 | Dec 17 | - | Well Go USA Entertainment |
| 31 | Try Harder! | $32,432 | 5 | $27,816 | 85.8% | 5 | Dec 3 | - | Greenwich Entertainment |
| 32 | The Novice | $24,322 | 36 | $12,301 | 50.6% | 36 | Dec 17 | - | IFC Films |
| 33 | Harper | $20,268 | 5 | $10,170 | 50.2% | 5 | Dec 15 | Feb 3 | Indican Pictures |
| 34 | Nights of Cabiria 2021 Re-release | $14,485 | 4 | $6,663 | 46% | 4 | Dec 17 | - | Rialto Pictures |
| 35 | The Hating Game | $5,600 | - | - | - | - | Dec 10 | - | Vertical Entertainment |
| 36 | Agnes | $2,113 | 6 | $1,433 | 67.8% | 5 | Dec 10 | - | Magnolia Pictures |
| 37 | Descarrilados | $462 | 10 | - | - | - | Dec 3 | - | Sony Pictures Releasing |
