| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | The Chronicles of Narnia: The Voyage of the Dawn Treader | - | - | - | $12,500,036 | 598 | $14,992,713 | Dec 3 | 20th Century Fox International | false |
| 2 | Three Steps Above Heaven | - | - | - | $11,350,891 | 393 | $13,475,662 | Dec 3 | Warner Bros. | false |
| 3 | Megamind | - | - | - | $8,498,694 | 595 | $9,807,726 | Dec 3 | Paramount Pictures International | false |
| 4 | Harry Potter and the Deathly Hallows: Part 1 | - | - | - | $5,007,224 | 689 | $19,017,186 | Nov 19 | Warner Bros. | false |
| 5 | Gulliver's Travels | - | - | - | $4,509,089 | 540 | $11,545,998 | Dec 22 | 20th Century Fox International | false |
| 6 | Little Fockers | - | - | - | $4,029,470 | 389 | $10,182,446 | Dec 22 | Paramount Pictures International | false |
| 7 | Biutiful | - | - | - | $3,715,003 | 207 | $4,576,349 | Dec 3 | United International Pictures | false |
| 8 | Tron: Legacy | - | - | - | $3,710,350 | 576 | $5,685,102 | Dec 17 | Walt Disney Pictures | false |
| 9 | Among Wolves | - | - | - | $2,688,605 | 237 | $4,224,250 | Nov 26 | Wanda Visión S.A. | false |
| 10 | The Last Circus | - | - | - | $1,996,626 | 303 | $3,126,895 | Dec 17 | Warner Bros. | false |
| 11 | Takers 2010 Re-release | - | - | - | $1,922,953 | 204 | $2,905,445 | Nov 26 | Sony Pictures Releasing | false |
| 12 | Skyline | - | - | - | $1,718,616 | 345 | $3,198,153 | Nov 26 | Aurum Films | false |
| 13 | Burlesque | - | - | - | $1,455,559 | 286 | $1,831,895 | Dec 17 | Sony Pictures Releasing | false |
| 14 | The King's Speech | - | - | - | $1,003,427 | 200 | $15,863,460 | Dec 24 | DeAPlaneta | false |
| 15 | Chloe | - | - | - | $950,792 | 118 | $1,379,169 | Nov 26 | - | false |
| 16 | Bruc, the Manhunt | - | - | - | $890,790 | 286 | $1,584,719 | Dec 22 | United International Pictures | false |
| 17 | Julia's Eyes | - | - | - | $864,804 | 365 | $9,301,221 | Oct 29 | United International Pictures | false |
| 18 | Beauty and the Beast 2010 3D Release | - | - | - | $609,455 | 279 | $2,243,575 | Nov 19 | Walt Disney Pictures | false |
| 19 | Bon appétit | - | - | - | $515,989 | 100 | $1,262,026 | Nov 12 | - | false |
| 20 | Unstoppable | - | - | - | $468,834 | 336 | $4,218,424 | Nov 12 | 20th Century Fox International | false |
| 21 | The Town | - | - | - | $400,569 | 228 | $5,106,974 | Oct 29 | Warner Bros. | false |
| 22 | Fair Game | - | - | - | $395,819 | 201 | $3,410,708 | Nov 5 | DeAPlaneta | false |
| 23 | Mao's Last Dancer | - | - | - | $367,466 | 70 | $1,243,460 | Dec 17 | - | false |
| 24 | Don Mendo Rock ¿La venganza? | - | - | - | $337,291 | 224 | $467,984 | Dec 17 | Aurum Films | false |
| 25 | Neds | - | - | - | $318,164 | 44 | $338,223 | Dec 3 | Golem Distribución | false |
| 26 | 18 Meals | - | - | - | $252,838 | 32 | $447,674 | Nov 19 | - | false |
| 27 | Todas las canciones hablan de mí | - | - | - | $231,330 | 30 | $290,142 | Dec 10 | Alta Films | false |
| 28 | Due Date | - | - | - | $218,725 | 302 | $3,905,948 | Nov 5 | Warner Bros. | false |
| 29 | The Way 2010 Re-release | - | - | - | $203,002 | 59 | $562,021 | Nov 19 | Filmax | false |
| 30 | Franklyn | - | - | - | $178,490 | 129 | $178,515 | Dec 10 | DeAPlaneta | false |
| 31 | The Social Network | - | - | - | $170,582 | 339 | $6,584,744 | Oct 15 | Sony Pictures Releasing | false |
| 32 | Magic Silver | - | - | - | $159,516 | 60 | $234,821 | Dec 17 | - | false |
| 33 | Certified Copy | - | - | - | $138,962 | 43 | $1,053,670 | Oct 29 | Wanda Visión S.A. | false |
| 34 | Flamenco Flamenco | - | - | - | $132,783 | 29 | $303,966 | Nov 19 | Alta Films | false |
| 35 | Tamara Drewe | - | - | - | $123,643 | 64 | $609,276 | Nov 12 | Alta Films | false |
| 36 | Loose Cannons | - | - | - | $114,169 | 42 | $321,923 | Dec 22 | Vértigo Films | false |
| 37 | Uncle Boonmee Who Can Recall His Past Lives | - | - | - | $85,976 | 15 | $123,310 | Nov 26 | Karma Films | false |
| 38 | Poetry | - | - | - | $83,221 | 8 | $155,966 | Nov 26 | Golem Distribución | false |
| 39 | Black Bread | - | - | - | $68,528 | 114 | $3,770,657 | Oct 15 | - | false |
| 40 | When You're Strange | - | - | - | $59,824 | 5 | $82,114 | Dec 10 | Avalon | false |
| 41 | Plans for Tomorrow | - | - | - | $56,046 | 30 | $133,543 | Nov 19 | - | false |
| 42 | The Other Guys | - | - | - | $55,075 | 251 | $1,443,642 | Nov 12 | Sony Pictures Releasing | false |
| 43 | The Mosquito Net | - | - | - | $45,700 | 23 | $126,716 | Nov 5 | - | false |
| 44 | Little King Macius 2010 Re-release | - | - | - | $41,615 | 30 | $83,671 | Dec 22 | - | false |
| 45 | The Nutcrackers | - | - | - | $39,737 | 90 | $356,509 | Oct 29 | Alta Films | false |
| 46 | Fake Orgasm | - | - | - | $38,246 | 3 | $52,386 | Dec 3 | - | false |
| 47 | On the Path | - | - | - | $36,771 | 20 | $101,538 | Nov 12 | Golem Distribución | false |
| 48 | Circuit | - | - | - | $31,798 | 15 | $63,741 | Nov 19 | - | false |
| 49 | La llegenda de l'innombrable | - | - | - | $30,006 | 5 | $30,006 | Dec 10 | 20th Century Fox International | false |
| 50 | Tales from the Golden Age 2009 Re-release | - | - | - | $28,761 | 8 | $44,663 | Dec 17 | Alta Films | false |
| 51 | Heartbreaker | - | - | - | $26,107 | 157 | $1,510,738 | Oct 22 | - | false |
| 52 | Happy End 2010 Re-release | - | - | - | $20,035 | 4 | $69,512 | Dec 3 | - | false |
| 53 | Home for Christmas | - | - | - | $17,334 | 20 | $30,883 | Dec 22 | Golem Distribución | false |
| 54 | Caracremada | - | - | - | $15,172 | 3 | $20,735 | Dec 10 | - | false |
| 55 | Film socialisme | - | - | - | $12,472 | 7 | $44,195 | Dec 17 | - | false |
| 56 | Easy A | - | - | - | $12,140 | 221 | $1,397,014 | Oct 29 | Sony Pictures Releasing | false |
| 57 | Exit Through the Gift Shop | - | - | - | $10,975 | 10 | $253,497 | Oct 8 | Avalon | false |
| 58 | Valentino y el clan del can 2010 Re-release | - | - | - | $10,133 | 8 | $13,092 | Dec 3 | - | false |
| 59 | Toys in the Attic 2010 Re-release | - | - | - | $9,510 | 9 | $14,276 | Dec 17 | - | false |
| 60 | My Father My Lord 2010 Re-release | - | - | - | $9,184 | 6 | $27,985 | Nov 19 | Karma Films | false |
| 61 | Cyrus | - | - | - | $8,054 | 36 | $94,389 | Nov 19 | 20th Century Fox International | false |
| 62 | Lock Up | - | - | - | $6,704 | 150 | $288,197 | Nov 12 | Filmax | false |
| 63 | La Bohème 2010 Re-release | - | - | - | $6,592 | 21 | $72,940 | Nov 5 | Karma Films | false |
| 64 | Nagore | - | - | - | $6,573 | 7 | $33,620 | Nov 12 | - | false |
| 65 | Bicicleta, cullera, poma | - | - | - | $6,425 | 24 | $348,747 | Oct 1 | Sagrera TV | false |
| 66 | Mystikal | - | - | - | $5,817 | 13 | $5,817 | Dec 3 | Barton Films | false |
| 67 | Las aventuras de Don Quijote | - | - | - | $5,237 | 27 | $45,236 | Dec 10 | - | false |
| 68 | Ways to Live Forever | - | - | - | $3,739 | 108 | $158,693 | Oct 29 | - | false |
| 69 | El tesoro del rey Midas | - | - | - | $3,061 | 27 | $42,310 | Nov 5 | Barton Films | false |
| 70 | Grown Ups | - | - | - | $2,425 | 328 | $8,507,573 | Jul 30 | Sony Pictures Releasing | false |
| 71 | How Much Does Your Building Weigh, Mr Foster? | - | - | - | $2,069 | 5 | $150,909 | Oct 8 | - | false |
| 72 | El idioma imposible | - | - | - | $1,897 | 6 | $6,414 | Nov 26 | Barton Films | false |
| 73 | Eat Pray Love | - | - | - | $1,757 | 345 | $6,698,018 | Sep 24 | Sony Pictures Releasing | false |
| 74 | Propios y extraños | - | - | - | $1,718 | 16 | $4,586 | Nov 26 | - | false |
| 75 | Un cine como tú en un país como éste | - | - | - | $1,021 | 1 | $4,101 | Dec 3 | - | false |
| 76 | Bed & Breakfast: Love is a Happy Accident | - | - | - | $728 | 1 | $728 | Dec 10 | - | false |
| 77 | The Karate Kid | - | - | - | $665 | 485 | $11,727,245 | Aug 27 | Sony Pictures Releasing | false |
| 78 | Machete | - | - | - | $11 | 254 | $2,003,454 | Oct 1 | Sony Pictures Releasing | false |
