| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Marley & Me | - | - | - | $72,444,071 | 3,505 | $143,153,751 | Dec 25 | Twentieth Century Fox | false |
| 2 | Four Christmases | - | - | - | $68,081,834 | 3,540 | $120,146,040 | Nov 26 | Warner Bros. | false |
| 3 | The Day the Earth Stood Still | - | - | - | $67,286,845 | 3,560 | $79,366,978 | Dec 12 | Twentieth Century Fox | false |
| 4 | Yes Man | - | - | - | $60,029,690 | 3,434 | $97,690,976 | Dec 19 | Warner Bros. | false |
| 5 | Bedtime Stories | - | - | - | $56,700,912 | 3,684 | $110,101,975 | Dec 25 | Walt Disney Studios Motion Pictures | false |
| 6 | The Curious Case of Benjamin Button | - | - | - | $52,666,148 | 2,988 | $127,509,326 | Dec 25 | Paramount Pictures | false |
| 7 | Twilight | - | - | - | $50,966,467 | 3,649 | $192,769,854 | Nov 21 | Summit Entertainment | false |
| 8 | Seven Pounds | - | - | - | $45,938,985 | 2,758 | $69,951,824 | Dec 19 | Sony Pictures Releasing | false |
| 9 | Valkyrie | - | - | - | $40,901,858 | 2,838 | $83,077,833 | Dec 25 | United Artists | false |
| 10 | Bolt | - | - | - | $38,531,639 | 3,654 | $114,053,579 | Nov 21 | Walt Disney Studios Motion Pictures | false |
| 11 | The Tale of Despereaux | - | - | - | $34,019,390 | 3,107 | $50,877,145 | Dec 19 | Universal Pictures | false |
| 12 | Australia | - | - | - | $25,131,152 | 2,721 | $49,554,002 | Nov 26 | Twentieth Century Fox | false |
| 13 | Quantum of Solace | - | - | - | $23,840,268 | 3,501 | $168,368,427 | Nov 14 | Sony Pictures Releasing | false |
| 14 | Slumdog Millionaire | - | - | - | $18,682,988 | 2,943 | $141,319,928 | Nov 12 | - | false |
| 15 | Madagascar: Escape 2 Africa | - | - | - | $16,621,565 | 4,065 | $180,010,950 | Nov 7 | DreamWorks | false |
| 16 | Transporter 3 | - | - | - | $13,444,873 | 2,626 | $31,715,062 | Nov 26 | Lionsgate Films | false |
| 17 | The Spirit | - | - | - | $13,067,406 | 2,509 | $19,806,188 | Dec 25 | Lionsgate Films | false |
| 18 | Milk | - | - | - | $12,652,853 | 882 | $31,841,299 | Nov 26 | Focus Features | false |
| 19 | Doubt | - | - | - | $11,810,755 | 1,287 | $33,446,470 | Dec 12 | Miramax | false |
| 20 | Role Models | - | - | - | $8,586,995 | 2,798 | $67,294,270 | Nov 7 | Universal Pictures | false |
| 21 | Punisher: War Zone | - | - | - | $8,050,977 | 2,508 | $8,050,977 | Dec 5 | Lionsgate Films | false |
| 22 | Cadillac Records | - | - | - | $7,844,196 | 701 | $8,195,551 | Dec 5 | Sony Pictures Releasing | false |
| 23 | Nothing Like the Holidays | - | - | - | $7,163,279 | 1,671 | $7,503,736 | Dec 12 | Overture Films | false |
| 24 | Gran Torino | - | - | - | $5,881,093 | 3,045 | $148,095,302 | Dec 12 | Warner Bros. | false |
| 25 | Frost/Nixon | - | - | - | $4,369,220 | 1,105 | $18,622,031 | Dec 5 | Universal Pictures | false |
| 26 | The Boy in the Striped Pajamas | - | - | - | $3,551,727 | 679 | $9,046,156 | Nov 7 | Miramax | false |
| 27 | Rab Ne Bana Di Jodi | - | - | - | $1,927,974 | 83 | $2,078,956 | Dec 12 | Yash Raj Films | false |
| 28 | Changeling | - | - | - | $1,748,585 | 1,896 | $35,739,802 | Oct 24 | Universal Pictures | false |
| 29 | Ghajini | - | - | - | $1,708,947 | 83 | $2,430,627 | Dec 24 | Adlabs Films | false |
| 30 | The Reader | - | - | - | $1,674,737 | 1,203 | $34,194,407 | Dec 10 | The Weinstein Company | false |
| 31 | Rachel Getting Married | - | - | - | $1,545,580 | 391 | $12,796,841 | Oct 3 | Sony Pictures Classics | false |
| 32 | The Polar Express 2008 IMAX Release | - | - | - | $1,371,256 | 26 | $1,705,694 | Nov 21 | Warner Bros. | false |
| 33 | The Wrestler | - | - | - | $1,169,379 | 776 | $26,238,243 | Dec 17 | - | false |
| 34 | Eagle Eye | - | - | - | $966,121 | 3,614 | $101,440,743 | Sep 26 | DreamWorks | false |
| 35 | High School Musical 3: Senior Year | - | - | - | $930,807 | 3,626 | $90,559,416 | Oct 24 | Walt Disney Studios Motion Pictures | false |
| 36 | Beverly Hills Chihuahua | - | - | - | $917,385 | 3,239 | $94,514,402 | Oct 3 | Walt Disney Studios Motion Pictures | false |
| 37 | I've Loved You So Long | - | - | - | $798,461 | 69 | $3,169,305 | Oct 24 | Sony Pictures Classics | false |
| 38 | Fireproof | - | - | - | $794,183 | 905 | $33,456,317 | Sep 26 | The Samuel Goldwyn Company | false |
| 39 | The Secret Life of Bees | - | - | - | $791,199 | 1,630 | $37,770,162 | Oct 17 | - | false |
| 40 | Synecdoche, New York | - | - | - | $785,233 | 119 | $3,083,538 | Oct 24 | Sony Pictures Classics | false |
| 41 | Zack and Miri Make a Porno | - | - | - | $773,937 | 2,735 | $31,457,946 | Oct 31 | The Weinstein Company | false |
| 42 | Delgo | - | - | - | $694,782 | 2,160 | $694,782 | Dec 12 | Freestyle Releasing | false |
| 43 | The Dark Knight | - | - | - | $665,937 | 4,366 | $533,345,358 | Jul 18 | Warner Bros. | false |
| 44 | Let the Right One In | - | - | - | $592,130 | 53 | $2,122,065 | Oct 24 | Magnolia Pictures | false |
| 45 | Happy-Go-Lucky | - | - | - | $579,185 | 202 | $3,512,016 | Oct 10 | Miramax | false |
| 46 | Nobel Son | - | - | - | $540,382 | 893 | $540,382 | Dec 5 | Freestyle Releasing | false |
| 47 | A Christmas Tale | - | - | - | $525,488 | 52 | $1,060,922 | Nov 14 | IFC Films | false |
| 48 | Magnificent Desolation: Walking on the Moon | - | - | - | $419,258 | 82 | $34,137,524 | Sep 23 | IMAX | false |
| 49 | Sea Monsters: A Prehistoric Adventure | - | - | - | $385,505 | 252 | $23,746,066 | Oct 5 | National Geographic Entertainment | false |
| 50 | Soul Men | - | - | - | $364,578 | 2,048 | $12,082,391 | Nov 7 | - | false |
| 51 | Santa vs. the Snowman 3D 2008 Re-release | - | - | - | $337,263 | 18 | $433,797 | Oct 31 | IMAX | false |
| 52 | Revolutionary Road | - | - | - | $313,469 | 1,077 | $22,911,480 | Dec 26 | Paramount Vantage | false |
| 53 | Body of Lies | - | - | - | $303,331 | 2,714 | $39,394,666 | Oct 10 | Warner Bros. | false |
| 54 | Vicky Cristina Barcelona | - | - | - | $294,565 | 726 | $23,216,709 | Aug 15 | - | false |
| 55 | Deep Sea | - | - | - | $224,441 | 47 | $46,412,757 | Mar 3 | Warner Bros. | false |
| 56 | Nights in Rodanthe | - | - | - | $217,750 | 2,704 | $41,850,659 | Sep 26 | Warner Bros. | false |
| 57 | Last Chance Harvey | - | - | - | $208,007 | 1,108 | $14,889,042 | Dec 25 | Overture Films | false |
| 58 | Max Payne | - | - | - | $206,832 | 3,381 | $40,689,393 | Oct 17 | Twentieth Century Fox | false |
| 59 | Igor | - | - | - | $203,131 | 2,341 | $19,528,602 | Sep 19 | Metro-Goldwyn-Mayer (MGM) | false |
| 60 | Fly Me to the Moon 3D | - | - | - | $197,326 | 713 | $13,816,982 | Aug 15 | Summit Entertainment | false |
| 61 | Space Station 3D | - | - | - | $195,440 | 64 | $93,383,953 | Apr 19 | IMAX | false |
| 62 | Burn After Reading | - | - | - | $185,559 | 2,657 | $60,355,347 | Sep 12 | Focus Features | false |
| 63 | JCVD | - | - | - | $176,137 | 28 | $470,691 | Nov 7 | - | false |
| 64 | Che: Part One/Che: Part Two | - | - | - | $173,606 | 39 | $1,497,109 | Dec 12 | IFC Films | false |
| 65 | Yuvvraaj | - | - | - | $146,070 | 77 | $570,090 | Nov 21 | Eros Worldwide | false |
| 66 | Appaloosa | - | - | - | $143,510 | 1,290 | $20,211,394 | Sep 19 | Warner Bros. | false |
| 67 | WALL·E | - | - | - | $133,287 | 3,992 | $223,808,164 | Jun 27 | Walt Disney Studios Motion Pictures | false |
| 68 | The Haunting of Molly Hartley | - | - | - | $132,195 | 2,652 | $13,559,812 | Oct 31 | Freestyle Releasing | false |
| 69 | Religulous | - | - | - | $121,425 | 568 | $13,011,160 | Oct 1 | Lionsgate Films | false |
| 70 | RocknRolla | - | - | - | $118,117 | 826 | $5,700,626 | Oct 8 | Warner Bros. | false |
| 71 | Friendship | - | - | - | $103,917 | 74 | $1,243,910 | Nov 14 | Yash Raj Films | false |
| 72 | Dolphins and Whales 3D: Tribes of the Ocean | - | - | - | $103,283 | 42 | $7,714,996 | Feb 15 | 3D Entertainment | false |
| 73 | Righteous Kill | - | - | - | $97,638 | 3,152 | $40,081,410 | Sep 12 | Overture Films | false |
| 74 | Saw V | - | - | - | $93,956 | 3,084 | $56,746,769 | Oct 24 | Lionsgate Films | false |
| 75 | Pride and Glory | - | - | - | $91,497 | 2,585 | $15,740,721 | Oct 24 | Warner Bros. | false |
| 76 | The Duchess | - | - | - | $89,136 | 1,207 | $13,848,978 | Sep 19 | Paramount Vantage | false |
| 77 | City of Ember | - | - | - | $87,609 | 2,023 | $7,873,007 | Oct 10 | Twentieth Century Fox | false |
| 78 | Wendy and Lucy | - | - | - | $83,123 | 40 | $865,695 | Dec 10 | Oscilloscope | false |
| 79 | A Secret | - | - | - | $58,558 | 11 | $623,558 | Sep 5 | Strand Releasing | false |
| 80 | Roving Mars | - | - | - | $55,606 | 27 | $10,407,978 | Jan 27 | Walt Disney Studios Motion Pictures | false |
| 81 | My Name Is Bruce | - | - | - | $53,366 | 4 | $173,066 | Oct 31 | Image Entertainment | false |
| 82 | Man on Wire | - | - | - | $52,844 | 93 | $2,962,242 | Jul 25 | Magnolia Pictures | false |
| 83 | Were the World Mine | - | - | - | $49,704 | 4 | $123,789 | Oct 31 | - | false |
| 84 | The Secrets | - | - | - | $42,751 | 9 | $122,094 | Nov 26 | Monterey Media | false |
| 85 | Oye Lucky! Lucky Oye! | - | - | - | $38,699 | 45 | $80,037 | Nov 26 | UTV Motion Pictures | false |
| 86 | Tell No One | - | - | - | $35,881 | 112 | $6,177,192 | Jul 2 | Music Box Films | false |
| 87 | Bottle Shock | - | - | - | $30,084 | 401 | $4,078,607 | Aug 6 | Freestyle Releasing | false |
| 88 | Call + Response | - | - | - | $29,697 | 17 | $215,185 | Oct 10 | Fair Trade Pictures | false |
| 89 | What Just Happened | - | - | - | $29,561 | 88 | $1,090,947 | Oct 17 | Magnolia Pictures | false |
| 90 | U2 3D | - | - | - | $28,949 | 686 | $10,363,341 | Jan 23 | National Geographic Entertainment | false |
| 91 | Pray the Devil Back to Hell | - | - | - | $28,442 | 5 | $90,066 | Nov 7 | Balcony Releasing | false |
| 92 | Don Carlo | - | - | - | $27,834 | 5 | $27,834 | Dec 5 | Emerging Pictures | false |
| 93 | Defiance | - | - | - | $25,237 | 1,793 | $28,644,813 | Dec 31 | Paramount Vantage | false |
| 94 | Harvard Beats Yale 29-29 | - | - | - | $25,208 | 13 | $268,431 | Nov 19 | Kino International | false |
| 95 | Frozen River | - | - | - | $25,187 | 96 | $2,511,476 | Aug 1 | Sony Pictures Classics | false |
| 96 | The Secret of the Grain | - | - | - | $22,351 | 3 | $86,356 | Dec 24 | IFC Films | false |
| 97 | I Served the King of England | - | - | - | $22,258 | 38 | $617,403 | Aug 29 | Sony Pictures Classics | false |
| 98 | Repo! The Genetic Opera | - | - | - | $22,100 | 11 | $146,750 | Nov 7 | Lionsgate Films | false |
| 99 | Ashes of Time | - | - | - | $21,950 | 18 | $174,273 | Oct 10 | Sony Pictures Classics | false |
| 100 | Noah's Arc: Jumping the Broom | - | - | - | $20,923 | 9 | $532,878 | Oct 24 | - | false |
| 101 | Timecrimes | - | - | - | $20,488 | 7 | $39,127 | Dec 12 | Magnolia Pictures | false |
| 102 | Ciao | - | - | - | $18,755 | 3 | $49,494 | Dec 5 | Regent Releasing | false |
| 103 | W. | - | - | - | $16,993 | 2,050 | $25,534,493 | Oct 17 | Lionsgate Films | false |
| 104 | Dark Streets | - | - | - | $16,815 | 18 | $16,815 | Dec 12 | The Samuel Goldwyn Company | false |
| 105 | A Girl Cut in Two | - | - | - | $16,669 | 21 | $409,658 | Aug 15 | IFC Films | false |
| 106 | Stranded | - | - | - | $16,190 | 7 | $89,473 | Oct 22 | Zeitgeist Films | false |
| 107 | How About You | - | - | - | $15,622 | 7 | $78,234 | Nov 14 | Strand Releasing | false |
| 108 | Trouble the Water | - | - | - | $15,242 | 15 | $520,151 | Aug 22 | Zeitgeist Films | false |
| 109 | I Can't Think Straight | - | - | - | $15,158 | 3 | $39,576 | Nov 21 | Regent Releasing | false |
| 110 | Journey to the Center of the Earth | - | - | - | $14,430 | 2,830 | $101,704,370 | Jul 11 | Warner Bros. | false |
| 111 | Hounddog | - | - | - | $11,441 | 11 | $131,961 | Sep 19 | Empire Pictures Inc. | false |
| 112 | How to Lose Friends & Alienate People | - | - | - | $10,742 | 1,750 | $2,778,752 | Oct 3 | Metro-Goldwyn-Mayer (MGM) | false |
| 113 | Gomorrah | - | - | - | $10,405 | 50 | $1,579,146 | Dec 19 | IFC Films | false |
| 114 | Fear(s) of the Dark | - | - | - | $10,343 | 8 | $77,876 | Oct 22 | IFC Films | false |
| 115 | A Good Day to Be Black & Sexy | - | - | - | $8,629 | 1 | $8,629 | Dec 5 | Magnolia Pictures | false |
| 116 | The Matador | - | - | - | $7,827 | 2 | $21,816 | Oct 31 | City Lights Pictures | false |
| 117 | Familiar Strangers | - | - | - | $7,328 | 4 | $34,068 | Nov 14 | Cavalier Films | false |
| 118 | Save Me | - | - | - | $7,132 | 5 | $83,397 | Sep 5 | First Run | false |
| 119 | Gardens of the Night | - | - | - | $6,311 | 1 | $11,436 | Nov 7 | City Lights Pictures | false |
| 120 | The Order of Myths | - | - | - | $6,269 | 3 | $62,645 | Jul 25 | The Cinema Guild | false |
| 121 | August Evening | - | - | - | $6,265 | 4 | $74,759 | Sep 5 | Maya Entertainment | false |
| 122 | Eden | - | - | - | $6,123 | 3 | $15,611 | Nov 14 | Liberation Entertainment | false |
| 123 | Breakfast with Scot | - | - | - | $5,802 | 6 | $46,060 | Oct 10 | Regent Releasing | false |
| 124 | Ballast | - | - | - | $5,770 | 5 | $77,556 | Oct 1 | Alluvial Film Company | false |
| 125 | Antarctica | - | - | - | $5,705 | 2 | $21,679 | Aug 29 | Regent Releasing | false |
| 126 | I.O.U.S.A. | - | - | - | $5,628 | 358 | $821,046 | Aug 22 | Roadside Attractions | false |
| 127 | Sex Drive | - | - | - | $5,543 | 2,421 | $8,402,485 | Oct 17 | Summit Entertainment | false |
| 128 | One Day You'll Understand | - | - | - | $5,503 | 7 | $145,642 | Oct 31 | Kino International | false |
| 129 | The Wild Child | - | - | - | $5,374 | 2 | $65,051 | Nov 7 | The Film Desk | false |
| 130 | House | - | - | - | $5,256 | 363 | $575,048 | Nov 7 | Roadside Attractions | false |
| 131 | Sky Kids | - | - | - | $4,662 | 17 | $144,680 | Aug 15 | Dark Coast Pictures | false |
| 132 | The Dukes | - | - | - | $4,354 | 11 | $26,875 | Nov 14 | - | false |
| 133 | Amexicano | - | - | - | $4,018 | 1 | $8,655 | Sep 19 | Maya Entertainment | false |
| 134 | Louise Bourgeois | - | - | - | $3,915 | 4 | $95,865 | Jun 25 | Zeitgeist Films | false |
| 135 | Where God Left His Shoes | - | - | - | $3,911 | 2 | $3,911 | Dec 12 | IFC Films | false |
| 136 | Waltz with Bashir | - | - | - | $3,892 | 208 | $2,283,849 | Dec 25 | Sony Pictures Classics | false |
| 137 | Flow: For Love of Water | - | - | - | $3,756 | 11 | $142,569 | Mar 21 | Oscilloscope | false |
| 138 | Hunger | - | - | - | $3,561 | 11 | $154,084 | Dec 5 | IFC Films | false |
| 139 | Good | - | - | - | $3,474 | 8 | $27,276 | Dec 31 | THINKFilm | false |
| 140 | Lola Montès | - | - | - | $3,451 | 4 | $120,306 | Oct 10 | Rialto Pictures | false |
| 141 | Monsieur Verdoux | - | - | - | $3,071 | 2 | $64,636 | Mar 14 | The Film Desk | false |
| 142 | The Alphabet Killer | - | - | - | $2,897 | 2 | $29,784 | Nov 7 | Anchor Bay Films | false |
| 143 | Box Elder | - | - | - | $2,556 | 2 | $48,996 | Mar 3 | - | false |
| 144 | Galapagos | - | - | - | $2,543 | 14 | $18,630,372 | Oct 29 | IMAX | false |
| 145 | Lake City | - | - | - | $2,148 | 2 | $12,767 | Nov 21 | Screen Media Films | false |
| 146 | The Betrayal | - | - | - | $1,924 | 3 | $41,271 | Nov 21 | The Cinema Guild | false |
| 147 | Haunted Castle | - | - | - | $1,728 | 10 | $13,651,656 | Feb 23 | - | false |
| 148 | Special 2008 Re-release | - | - | - | $1,536 | 1 | $7,202 | Nov 21 | Magnolia Pictures | false |
| 149 | The First Basket | - | - | - | $1,445 | 4 | $20,440 | Oct 29 | - | false |
| 150 | Yella | - | - | - | $1,208 | 2 | $30,647 | May 16 | The Cinema Guild | false |
| 151 | Moving Midway | - | - | - | $1,203 | 4 | $40,864 | Sep 12 | First Run | false |
| 152 | Battle in Seattle | - | - | - | $1,118 | 40 | $224,169 | Sep 19 | Redwood Palms Pictures | false |
| 153 | $9.99 | - | - | - | $781 | 4 | $52,384 | Dec 12 | Regent Releasing | false |
| 154 | Otto; or, Up with Dead People | - | - | - | $776 | 2 | $11,295 | Nov 7 | Strand Releasing | false |
| 155 | Momma's Man | - | - | - | $643 | 9 | $100,435 | Aug 22 | Kino International | false |
| 156 | Whaledreamers | - | - | - | $612 | 6 | $10,584 | Sep 26 | Monterey Media | false |
| 157 | The Other End of the Line | - | - | - | $568 | 91 | $115,592 | Oct 31 | Metro-Goldwyn-Mayer (MGM) | false |
| 158 | A Man Named Pearl | - | - | - | $400 | 9 | $208,392 | Aug 31 | Tentmakers Entertainment | false |
| 159 | Rome & Jewel | - | - | - | $268 | 1 | $470 | Nov 28 | Emerging Pictures | false |
| 160 | The Pool | - | - | - | $196 | 8 | $95,102 | Sep 3 | Vitagraph Films | false |
| 161 | House of the Sleeping Beauties | - | - | - | $136 | 1 | $4,509 | Nov 14 | First Run | false |
