| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Natale in crociera | - | - | - | $27,589,355 | 581 | $36,800,000 | Dec 14 | Filmauro | false |
| 2 | A Beautiful Wife | - | - | - | $21,001,228 | 546 | $29,502,958 | Dec 14 | Medusa Distribuzione | false |
| 3 | The Golden Compass | - | - | - | $9,637,598 | 379 | $13,784,599 | Dec 14 | 01 Distribution | false |
| 4 | Enchanted | - | - | - | $8,316,410 | 404 | $10,816,852 | Dec 7 | Walt Disney Pictures | false |
| 5 | National Treasure: Book of Secrets | - | - | - | $7,354,973 | 348 | $13,168,731 | Dec 21 | Walt Disney Pictures | false |
| 6 | Winx Club: The Secret of the Lost Kingdom | - | - | - | $6,619,204 | 532 | $6,782,111 | Nov 30 | 01 Distribution | false |
| 7 | Bee Movie | - | - | - | $5,283,836 | 368 | $9,595,892 | Dec 21 | Universal Pictures International (UPI) | false |
| 8 | Matrimonio alle Bahamas | - | - | - | $4,599,289 | 461 | $15,471,233 | Nov 16 | Medusa Distribuzione | false |
| 9 | Lions for Lambs | - | - | - | $3,582,601 | 189 | $8,321,849 | Dec 21 | 20th Century Fox International | false |
| 10 | Milan Palermo - The Return | - | - | - | $3,118,472 | 251 | $5,801,888 | Nov 23 | Walt Disney Pictures | false |
| 11 | 1408 | - | - | - | $2,853,852 | 228 | $5,542,670 | Nov 23 | Lucky Red | false |
| 12 | Eastern Promises | - | - | - | $2,798,132 | 164 | $4,696,527 | Dec 14 | Eagle Pictures | false |
| 13 | Love in the Time of Cholera | - | - | - | $2,551,026 | 203 | $5,462,115 | Dec 21 | 01 Distribution | false |
| 14 | Lezioni di cioccolato | - | - | - | $2,329,198 | 212 | $3,909,492 | Nov 23 | Universal Pictures International (UPI) | false |
| 15 | In the Valley of Elah | - | - | - | $2,079,944 | 180 | $2,465,643 | Nov 30 | Mikado Film | false |
| 16 | Hitman | - | - | - | $1,957,891 | 224 | $1,977,980 | Dec 7 | 20th Century Fox International | false |
| 17 | August Rush | - | - | - | $1,558,481 | 190 | $1,462,687 | Nov 30 | Medusa Distribuzione | false |
| 18 | The Heartbreak Kid | - | - | - | $1,283,915 | 293 | $8,754,310 | Nov 9 | Universal Pictures International (UPI) | false |
| 19 | Come tu mi vuoi | - | - | - | $1,280,320 | 367 | $10,947,653 | Nov 9 | Medusa Distribuzione | false |
| 20 | Irina Palm | - | - | - | $1,109,655 | 54 | $2,612,727 | Dec 7 | Teodora Film | false |
| 21 | Beowulf | - | - | - | $836,183 | 368 | $5,072,906 | Nov 16 | Warner Bros. | false |
| 22 | Paranoid Park | - | - | - | $741,537 | 69 | $941,585 | Dec 7 | Lucky Red | false |
| 23 | The Nanny Diaries | - | - | - | $582,691 | 121 | $587,786 | Nov 30 | 01 Distribution | false |
| 24 | Days of Darkness | - | - | - | $559,475 | 36 | $793,131 | Dec 7 | BIM Distribuzione | false |
| 25 | Across the Universe | - | - | - | $517,494 | 77 | $1,227,260 | Nov 23 | Sony Pictures Releasing | false |
| 26 | The Kingdom | - | - | - | $507,756 | 102 | $851,352 | Nov 30 | Universal Pictures International (UPI) | false |
| 27 | I Viceré | - | - | - | $429,898 | 187 | $2,584,556 | Nov 9 | 01 Distribution | false |
| 28 | Don't Waste Your Time, Johnny! | - | - | - | $419,699 | 64 | $664,266 | Nov 30 | Medusa Distribuzione | false |
| 29 | Caramel | - | - | - | $413,862 | 50 | $2,301,033 | Dec 21 | Archibald | false |
| 30 | The Assassination of Jesse James by the Coward Robert Ford | - | - | - | $386,894 | 83 | $577,583 | Dec 21 | Warner Bros. | false |
| 31 | Ratatouille | - | - | - | $380,348 | 658 | $25,880,003 | Oct 19 | Walt Disney Pictures | false |
| 32 | Days and Clouds | - | - | - | $291,728 | 214 | $6,010,383 | Oct 26 | Warner Bros. | false |
| 33 | Fred Claus | - | - | - | $288,393 | 93 | $288,393 | Nov 30 | Warner Bros. | false |
| 34 | Conversations with My Gardener | - | - | - | $239,556 | 30 | $422,659 | Nov 23 | BIM Distribuzione | false |
| 35 | Fracture | - | - | - | $197,055 | 192 | $3,521,113 | Nov 2 | Eagle Pictures | false |
| 36 | Elizabeth: The Golden Age | - | - | - | $171,097 | 333 | $6,808,077 | Oct 26 | Universal Pictures International (UPI) | false |
| 37 | The Edge of Heaven | - | - | - | $152,545 | 47 | $674,318 | Nov 9 | BIM Distribuzione | false |
| 38 | The Hideout | - | - | - | $96,482 | 209 | $1,569,094 | Nov 16 | 01 Distribution | false |
| 39 | O Jerusalem | - | - | - | $89,952 | 23 | $208,544 | Nov 23 | Medusa Distribuzione | false |
| 40 | The Right Distance | - | - | - | $85,884 | 102 | $1,495,120 | Oct 19 | 01 Distribution | false |
| 41 | The Nightmare Before Christmas 2008 3D Release | - | - | - | $82,133 | 9 | $144,321 | Nov 30 | Walt Disney Pictures | false |
| 42 | Factory Girl | - | - | - | $80,249 | 39 | $225,101 | Nov 23 | Moviemax | false |
| 43 | Sleuth | - | - | - | $77,340 | 63 | $687,786 | Nov 9 | Sony Pictures Releasing | false |
| 44 | Jellyfish | - | - | - | $77,188 | 13 | $226,959 | Nov 16 | Sacher Distribuzione | false |
| 45 | Little Boy Red | - | - | - | $60,604 | 6 | $227,801 | Nov 16 | - | false |
| 46 | Blade Runner The Final Cut (2007 re-release) | - | - | - | $41,382 | 6 | $41,382 | Nov 30 | Warner Bros. | false |
| 47 | The Romance of Astrea and Celadon | - | - | - | $31,285 | 23 | $267,745 | Aug 31 | BIM Distribuzione | false |
| 48 | L'abbuffata | - | - | - | $29,657 | 88 | $220,414 | Nov 16 | Istituto Luce | false |
| 49 | The Wind Blows Round | - | - | - | $28,719 | 15 | $659,151 | May 4 | Aranciafilm | false |
| 50 | The Tiger Brigades | - | - | - | $27,215 | 28 | $27,215 | Dec 7 | Independent Films | false |
| 51 | SMS - Sotto mentite spoglie | - | - | - | $25,349 | 340 | $7,733,366 | Oct 12 | Medusa Distribuzione | false |
| 52 | Civico zero | - | - | - | $22,517 | 2 | $35,233 | Nov 23 | Istituto Luce | false |
| 53 | The Kingdom | - | - | - | $18,247 | 2 | $61,106 | Dec 21 | Lucky Red | false |
| 54 | Surf's Up | - | - | - | $17,793 | 246 | $2,351,388 | Oct 5 | Sony Pictures Releasing | false |
| 55 | My Führer | - | - | - | $15,698 | 56 | $145,077 | Nov 23 | Warner Bros. | false |
| 56 | The Ball | - | - | - | $14,659 | 4 | $306,304 | Mar 30 | Independent Films | false |
| 57 | Youth Without Youth | - | - | - | $14,069 | 77 | $923,196 | Oct 26 | BIM Distribuzione | false |
| 58 | The Seeker: The Dark Is Rising | - | - | - | $13,475 | 97 | $190,572 | Nov 23 | 20th Century Fox International | false |
| 59 | Welcome to the Roses 2007 Re-release | - | - | - | $12,310 | 16 | $375,465 | Oct 19 | Moviemax | false |
| 60 | Palermo-Milan One Way | - | - | - | $12,276 | 3 | $2,269,305 | Jan 24 | - | false |
| 61 | Silk | - | - | - | $10,953 | 197 | $1,615,449 | Oct 26 | Medusa Distribuzione | false |
| 62 | Michael Clayton | - | - | - | $8,023 | 380 | $6,289,332 | Oct 5 | Medusa Distribuzione | false |
| 63 | Music of the Heart 2001 Re-release | - | - | - | $7,187 | 3 | $77,013 | Apr 13 | - | false |
| 64 | Regular Lovers | - | - | - | $3,314 | 1 | $114,678 | - | Istituto Luce | false |
| 65 | Rabbit-Proof Fence | - | - | - | $2,687 | 16 | $55,023 | Nov 22 | Buena Vista International | false |
| 66 | It's a Boy Girl Thing | - | - | - | $2,358 | 34 | $54,399 | Nov 23 | Eagle Pictures | false |
| 67 | Beowulf | - | - | - | $2,221 | 2 | $102,744 | May 7 | Buena Vista International | false |
| 68 | Io non c'entro | - | - | - | $2,171 | 2 | $13,908 | Nov 30 | Independent Films | false |
| 69 | Stardust | - | - | - | $2,003 | 362 | $3,233,911 | Oct 12 | Universal Pictures International (UPI) | false |
| 70 | A Mighty Heart | - | - | - | $1,637 | 14 | $49,722 | Nov 16 | Universal Pictures International (UPI) | false |
| 71 | Terapia Roosevelt | - | - | - | $1,531 | 23 | $205,673 | Jun 1 | Independent Films | false |
| 72 | Felix: Around the World | - | - | - | $1,243 | 91 | $505,116 | Jan 20 | Moviemax | false |
| 73 | Rocco and His Brothers Undated Italy Release | - | - | - | $1,129 | 1 | $11,328 | - | Istituto Luce | false |
| 74 | My Brother is an Only Child | - | - | - | $1,103 | 482 | $9,406,247 | Apr 20 | Warner Bros. | false |
| 75 | XXY | - | - | - | $976 | 30 | $432,690 | Jun 22 | Teodora Film | false |
| 76 | Death at a Funeral | - | - | - | $586 | 218 | $3,318,228 | Sep 21 | Mikado Film | false |
| 77 | Open Season | - | - | - | $451 | 375 | $4,338,099 | Dec 7 | Sony Pictures Releasing | false |
| 78 | Una ballata bianca | - | - | - | $59 | 1 | $1,074 | Dec 7 | Independent Films | false |
